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Scripps research-designed drug candidate significantly reduces HIV reactivation rate

HIV-infected patients remain on antiretroviral therapy for life because the virus survives over the long-term in infected dormant cells. Interruption of current types of antiretroviral therapy results in a rebound of the virus and clinical progression to AIDS. Read More

A Toxic Chemical Compound Will be Generated in the Roaster Process of Coffee Beans

BOC Sciencs-Scientists found that a common food additive diacetyl can bring great damage to lungs when it be inhaled. And workers who roast coffee beans and make popcorn have frequent contact with the substance, that's one of the main reason that workers at these post will contract serious lung ... Read More

Drug Resistant Microbes were Found in African Wildlife

BOC Sciences-Drug resistance has always been one of the issues that scientists work hard to find ways out for better diseases treatment, as it hinders many drugs that were developed with much effort from taking effect in the body. And till now, there is little known about the formation of antibi... Read More

Stopping malaria in its tracks

A new drug acts as a roadblock for malaria, curing mice of established infection, according to a study in The Journal of Experimental Medicine. Treatment was not associated with obvious side effects, suggesting that the drug may also be safe and effective in humans. Read More

Study identifies new way to kill the malaria parasite

Scientists have discovered new ways in which the malaria parasite survives in the blood stream of its victims, a discovery that could pave the way to new treatments for the disease.

The researchers at the Medical Research Council's (MRC) Toxicology Unit based at the University of Leicester an... Read More

TWiV 301: Marine viruses and insect defense

At the International Congress of Virology in Montreal, Vincent speaks with Carla and Curtis about their work on RNA interference and antiviral defense in fruit flies, and viruses in the sea, the greatest biodiversity on Earth.


Host:  Read More

One in four hepatitis C patients denied initial approval for drug treatment

New Haven, Conn. -- Nearly one in four patients with chronic hepatitis C (HCV) are denied initial approval for a drug therapy that treats the most common strain of the infection, according to a Yale School of Medicine study. Read More

HIV uses the immune system's own tools to suppress it

A Canadian research team at the IRCM in Montreal, led by molecular virologist Eric A. Cohen, PhD, made a significant discovery on how HIV escapes the body's antiviral responses. The team uncovered how an HIV viral protein known as Vpu tricks the immune system by using its own regulatory process ... Read More

Virus-like particle vaccine protects mice from many flu strains

A vaccine that protects against a wide variety of influenza viruses (a so-called universal flu vaccine) is a critical public health goal given the significant rates of illness and death caused by seasonal influenza and the potentially devastating effects of a pandemic influenza strain. Now, rese... Read More

Researchers develop world's most sensitive test to detect infectious disease, superbugs

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens. Read More

Single dose Ebola vaccine is safe and effective in monkeys against outbreak strain

National Institutes of Health (NIH) scientists report that a single dose of an experimental Ebola virus (EBOV) vaccine completely protects cynomolgus macaques against the current EBOV outbreak strain, EBOV-Makona, when given at least seven days before exposure, and partially protects them if giv... Read More

MdlM113: Microorganismos Halofilos Extremos y los virus que las infectan con Josefa Anton

Ambientes extremos: salares del mundo, su microbiota y los virus presentes. Estos son los temas a discutirse en el episodio de hoy de La Radio el Mundo de los Microbios. Nuestra invitada la Dra. Josefa (Pepa) Anton, Catedrática Asociada de la Universidad de Alicante compartirá sus estudios so... Read More

BacterioFiles 209 - Myxococcus Menace Motivates Megastructures

This episode: Microbial predators in soil cause microbial prey to build fortifications!


(8.8 MB, 9.5 minutes)


Show notes: 
Journal Paper


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Why West Nile virus is more dangerous in the elderly

West Nile virus (WNV) is particularly dangerous in older people, who account for a large number of severe cases and deaths caused by the virus. WNV infection turns serious when the virus crosses the blood-brain-barrier and wreaks havoc among nerve cells in the brain. A study published on July 23... Read More

Crime-scene compound may be newest tool in fight against malaria

The compound that detectives spray at crime scenes to find trace amounts of blood may be used one day to kill the malaria parasite. Read More

What's lurking in your lungs? Surprising findings emerge from U-M microbiome research

ANN ARBOR, Mich. -- With every breath you take, microbes have a chance of making it into your lungs. But what happens when they get there? And why do dangerous lung infections like pneumonia happen in some people, but not others? Read More

The sting in dengue's tail

In a new Science study, Duke-NUS Graduate Medical School Singapore (Duke-NUS) scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defences and spread more efficiently. This research is the first of its kind that examined ... Read More

Evolutionary war between microorganisms affecting human health, IU biologist says

BLOOMINGTON, Ind. -- Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection. Read More

TWiP 91: Born to deform

 Vincent, Dickson, and Daniel review how Viagra might be used to block transmission of Plasmodium falciparum, and introduce a new case study.


Hosts:  Read More

1977 H1N1 influenza virus is not relevant to the gain of function debate

The individuals who believe that certain types of gain-of-function experiments should not be done because they are too dangerous (including Lipsitch, Osterholm, Wain-Hobson,) cite the 1977 influenza virus H1N1 strain as an example of a laboratory accident that has led to a global epidemic. A new... Read More
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