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Getting Started with MicrobeWorld

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TWiV 381: Add viruses and Zimmer

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Prion contamination in the emergency room

Here is a follow-up to last week’s article that described a case of variant Creutzfeldt-Jacob disease in a Texas resident caused by ingestion of BSE-contaminated beef 14 years ago.

A 59 year old male patient was admitted to the trauma unit in Lancaster, PA with a self-inflicted gunshot wound ... Read More

Likely Drug Interactions In Placenta Could Harm Fetus

Washington, DC - October 13, 2015 - To date, studies in pregnant women examining transport of drugs across the placenta are rare and inadequate, said Tomo Nabekura, PhD. Such knowledge could be vital to preserving fetal health. In a new laboratory study, Nabekura and colleagues have illuminated ... Read More

Bacteriophage Treatment Decontaminates Infant Formula

Washington, DC – October 23, 2015 - A phage showed strong anti-microbial activity against a type of food-borne bacterium that often kills infants after infecting them via infant formula. Phages are viruses that infect only bacteria. The research is published October 23 online in Applied and Envi... Read More

ZIKA VIRUS ‘IS ABOUT AS SCARY AS IT GETS’

The Zika virus, unlike other mosquito-borne viruses such as dengue, has until now been relatively unknown and unstudied. Read More

HIV patients should be included in early clinical trials of anti-TB drugs

Amsterdam, The Netherlands: Tuberculosis is the number one cause of death in HIV-infected patients in Africa and a leading cause of death in this population worldwide, yet the majority of these patients are excluded from the early stages in the development of new, anti-tuberculosis drugs, accord... Read More

TWiM 126 Letters

 


Anthony writes:
An Abandoned Sailor’s Infirmary in NYC Where Cholera Bacteria Was Discovered
http://untappedcities.com/2016/03/... Read More

Partnership to develop production system for exciting new antibiotic

Researchers from Plymouth University are collaborating with world-leading industrial biotechnology and synthetic biology business Ingenza, to develop an efficient, scalable microbial production system for epidermicin, a new class of antibiotic being developed for use in the fight against infecti... Read More

BacterioFiles 257 - Phage Fibers Fight Phyllosphere Foes

This episode: Bacteria have repeatedly captured and used the tails of phages to fight each other!


(9 MB, 9.8 minutes)


Show notes: 
Journal Paper:

Hockett KL, Renner T, Baltrus DA. 2015. Read More

Sendai virus defends against a threat

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal tran... Read More

First hospital-based rapid detection Zika test now available

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus. Read More

MMP #12: Hydrogen from ground rocks can furnish microbial ecosystems with energy to drive growth.

Host: Jeff Fox with special guest, Jon Telling.


Jon Telling of Bristol University in Bristol, United Kingdom talks with Jeff Fox about his findings suggesting that the grinding of glaciers over rocks can liberate hydrogen, which, in turn, drives the growth of methanogens within microb... Read More

Plague infected humans much earlier than previously thought

Plague infections were common in humans 3,300 years earlier than the historical record suggests, reports a study published October 22 in Cell. By sequencing the DNA of tooth samples from Bronze Age individuals from Europe and Asia, the researchers discovered evidence of plague infections roughly... Read More

TWiM #133: Right under our noses

Insight into the biology of rhinovirus C from cryo-electron microscopy, and a novel antibiotic from a commensal bacterium that grows in the human nose, from the doctors of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter, an... Read More

Zolav®: A new antibiotic for the treatment of acne

A scientific paper released today in the Journal of Drug Design, Development and Therapy show the effectiveness of Zolav®, a new antibiotic, in treating acne. Read More

NYU research: Severe liver damage in mid/late-adulthood among PWID with chronic HCV

The Hepatitis C virus (HCV) infection is a chronic blood-borne viral infection that affects an estimated 160 million people, or 2-3% of the population world-wide. Alarmingly, chronic HCV infection accounts for one-quarter of the cases of cirrhosis and hepatocellular carcinoma (HCC). If HCV is le... Read More

Ebola crisis provides framework for responding to outbreaks like Zika virus

PRINCETON, N.J.--As world leaders grapple with containing the Zika virus, the Ebola epidemic in West Africa provides valuable lessons for how to respond to infectious disease epidemics, according to a policy report published by researchers at Princeton University and the Wellcome Trust. Read More

Molecular 'kiss of death' flags pathogens

DURHAM, N.C. -- Many bugs that make us sick -- bacteria, viruses, fungi and parasites -- hide out in our cells in protective little bubbles called vacuoles. To clear an infection, the immune system must recognize and destroy these vacuoles while leaving the rest of the living cell intact. Read More

Viral variation in single cells

It is well known that virus populations display phenomenal diversity. Virus populations are dynamic distributions of nonidentical but related members called a quasispecies. This diversity is restricted in single cells, but is restored within two infectious cycles. Read More

Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More
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