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ASM GM 2014 - The Effect of Pancreatic Cancer on the Oral Microbiome

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More

UNC researchers discover new target for dengue virus vaccine

Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More

Bacteria and hand washing Pragmatic to school children in rural Nepal

Hand washing is thought to be effective for the prevention of transmission of
Diarrhea pathogens. However it is not conclusive that hand washing with soap is more
Effective at reducing contamination with bacteria associated with diarrhea than using water only. Read More

Bacteria show surprising number of genetic paths to survival

A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults from his immune system and antibiotics, while others perish. Eventually, the strongest m... Read More

Researchers open door to new HIV therapy

BERKELEY — People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos. Researchers at the Unive... Read More

Zaire ebolavirus in West Africa

Dr. Tom Solomon is Director of the Institute for Infection and Global Health at the University of Liverpool. In this video he speaks with Vincent Racaniello about the 2014 outbreak of Zaire ebolavirus in West Africa. Dr. Solomon discusses why the epidemic has spread, how it might be curtailed, t... Read More

On Teaching

A graduate student came to my office recently to say that she was increasingly bothered by anxiety and the ‘terror’ of having to speak at laboratory meetings. She had also learned a month ago that she was expected to lecture to a class organized by her mentor. The thought of having to lecture to... Read More

Yes! We have no bananas? It could actually happen

Banana lovers take note: The world's supply of the fruit is under attack from a fungus strain that could wipe out the popular variety that Americans eat. "It's a very serious situation," said Randy Ploetz, a professor of plant pathology at the University of Florida who in 1989 originally discove... Read More

Amber discovery indicates Lyme disease is older than human race

Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago, but new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years – long before any humans walked on Earth.

The findings w... Read More

New research reveals how bacteria construct tiny flagella ‘nanomachines’ outside the cell

Cambridge scientists have uncovered the mechanism by which bacteria build their surface propellers (flagella) – the long extensions that allow them to swim towards food and away from danger. The results, published this week in the journal Nature, demonstrate how the mechanism is powered by the s... Read More

Ebola genomes sequenced

Speedy analysis reveals mutations, insights into outbreak, along with clues to origin, spread.

Responding rapidly to the deadly outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard University, working with the Sierra Leone Ministry o... Read More

DIY Droplet Lens, finalist, 2014 Eureka Prize for Innovative Use of Technology

The traditional light microscope is bulky and expensive. Dr Tri Phan and Dr Steve Lee from the Garvan Institute of Medical Research and Australian National University used gravity to manufacture high-performance polymer lenses. These can be seamlessly integrated with 3D printing and mini-LEDs to... Read More

Reduced glycopeptide and lipopeptide susceptibility in Staphylococcus aureus and the “seesaw effect”: Taking advantage of the back door left open?

Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More

New Wearable Device Could Protect Against HIV and Pregnancy

If a sexually active woman wants to protect herself from unwanted pregnancy and HIV using a single method, she has always been limited to condoms. A new paper, released today in PLOS ONE details a first-of-its-kind device that provides an alternative.

Click on 'source' to read full artlicle.... Read More

Gut Bacteria Lose their Tails to Evade Antibodies

New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.

In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More

Old drug may be key to new antibiotics

McMaster scientists have found that an anticonvulsant drug may help in developing a new class of antibiotics.

Although dozens of antibiotics target what bacteria do, their study has looked at how a certain part of bacteria are created, and they found there is a way of stopping it.

The disc... Read More

Healthy humans make nice homes for viruses

The same viruses that make us sick can take up residence in and on the human body without provoking a sneeze, cough or other troublesome symptom, according to new research. On average, healthy individuals carry about five types of viruses on their bodies, the researchers report. The study is the... Read More

Tiny Algae Responsible for Mysterious Fossil Whale Graveyard?

Ever since a highway construction crew in Chile uncovered a fossil graveyard of some 40 prehistoric whales in 2010, with skeletons dating back more than five million years, scientists have wondered why so many giant animals died in one place. This week, a team of them proposed an answer: The hug... Read More

Reprogrammed Bacteria Build Self-Healing ‘Living Materials’

How handy would it be if, instead of taking your broken circuit board to the Genius Bar (again), you could just prompt it to heal itself? That’s the futuristic possibility researchers have recently inched ever so slightly toward, with the development of hybrid “living materials” made from bacter... Read More

How brain guards itself against virus attacks

Infections in the central nervous system are rare thanks to our brain's unique defence system that prevents viruses from invading, finds a study. The research explains a long-standing mystery.

Click 'source' to read more. Read More

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