A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely—and more stealthily—than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.
Researchers examined carbapenem resi... Read More
Before infecting humans, tick-borne bacteria or viruses first have to get past a tick’s defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection in the United States, human granulocytic anapla... Read More
The technique that the hepatitis E virus — an emerging liver virus historically found in developing countries but now on the rise in Europe — uses to spread could present a weak spot scientists can exploit to treat the disease, according to a new study.
Princeton University-led researchers re... Read More
The Rapid Drug Susceptibility Testing Consortium (RDST), coordinated by the Critical Path Institute (C-Path) through the Critical Path to TB Drug Regimens (CPTR) initiative, announces the public launch of the Relational Sequencing TB Data Platform (ReSeqTB). ReSeqTB is a data-sharing platform an... Read More
A generation ago, two antibiotic strategies known as cycling and mixing were employed to outwit bacteria. Cycling is like antibiotic crop rotation where certain classes of antibiotics are withdrawn for a period of time. Doctors thought this would combat resistance because bacterial pathogens wou... Read More
A multidisciplinary team of researchers at KU Leuven (University of Leuven, Belgium) has developed a dental implant that gradually releases drugs from a built-in reservoir. This helps prevent and fight infections.
Our mouth contains many micro-organisms, including bacterial and fungal pathoge... Read More
They’re on your tongue, under your armpits, in your guts and on your skin. In fact, any place you can think of there are microbes living on, under, or in between there. In their unimaginably large numbers, these micro-organisms determine our lives – even though we never see them. Micropia, the w... Read More
It has been assumed that mothers pass on gut microbes to their infants during and just after delivery, a process called vertical transmission, but because of technical restraints, the evidence of this occurring has been limited. Previous cultivation-free studies have observed the same microbial ... Read More
Poor diagnosis worldwide of fungal disease causes doctors to overprescribe antibiotics, increasing harmful resistance to antimicrobial drugs, according to a paper published today in Emerging Infectious Diseases.
“Inadequate attention is paid to fungal infection as the cause of antibacterial t... Read More
A new tool -- a type of ultraviolet light called UVC -- could aid hospitals in the ongoing battle to keep drug-resistant bacteria from lingering in patient rooms and causing new infections.
Some hospitals have already begun using UVC machines in addition to standard chemical disinfection to k... Read More
Drugs used to treat HIV could affect how the body responds to syphilis, inadvertently contributing to a current outbreak, a new study suggests.
In this study, researchers investigating the outbreak hypothesize that medications used in highly active antiretroviral therapy (HAART), the gold sta... Read More
A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania. Publishing in Cell Reports t... Read More
New research conducted at the University of Miami in Coral Gables, Florida and the National Cancer Institute, in Bethesda, Maryland demonstrate that a subset of bacteriophages, dubbed “superspreaders,” potentially play a major role in transmitting antimicrobial resistance. The research, describe... Read More
Trudy joins the the TWiVlords to discuss new tests for detecting prions in the blood, and evidence showing that foamy retroviruses originated in the seas with their jawed vertebrate hosts at least 450 million years ago.
Hosts: Read More
Many mBiosphere readers will know that the influenza A virus infects multiple species, and this ability to infect birds, humans, and other mammals such as pigs is one of the ways virions can exchange genetic information, leading to new viruses able to cause major outbreaks. However, few mBiosphe... Read More
The world has a problem: an exploding human population, which will require crop yields to double by 2050 without increasing crop acreage. Solving this problem will necessitate help from some of the smallest members of Earth’s population using a concept that has both George Washington Carver and ... Read More
With Chagas disease becoming more prevalent in the United States, a diagnostic to quickly and easily detect infection is needed. Today, IDRI (Infectious Disease Research Institute) announces that a fusion antigen it developed and patented is being used as part of a Chagas disease diagnostic test... Read More
Although cases of Zika virus infection appear to be decreasing, the mosquito-borne virus likely will become endemic in the Americas and continue to cause outbreaks and sporadic cases. Given the serious complications of Zika virus infection, particularly in cases of congenital infection, research... Read More
If it sometimes seems like the idea of antibiotic resistance, though unsettling, is more theoretical than real, please read on.
Public health officials from Nevada are reporting on a case of a woman who died in Reno in September from an incurable infection. Testing showed the superbug that ha... Read More
A team of researchers from the Massachusetts General Hospital (MGH) and the Ragon Institute of MGH, MIT and Harvard has found that the most common bacterial community in the genital tract of healthy South African women is associated with a more than four-fold increase in the risk of acquiring HI... Read More