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False impressions in predatory publishing

Imitation may be the sincerest form of flattery, but it can also be the easiest way to make a buck. That’s the primary motivation for camouflaging within an already-established brand: Sunbucks, McDowell’s, and Mountain Lightening all rely on brand recognition – of a brand that isn’t their own. W... Read More

Microbes After Hours: Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathoge... Read More

BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!

(11.1 MB, 12.1 minutes)

Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

TWiV 396: Influenza viruses with Peter Palese

Vincent speaks with Peter Palese about his illustrious career in virology, from early work on neuraminidases to universal influenza virus vaccines.

Host: Vincent Racaniello 

Guest:&nbs... Read More

Vibrio cholerae population structure changes in a matter of weeks

Although the Gram-negative bacterium Vibrio cholerae (right) is normally associated with human pathogenic disease, most V. cholerae cells spend their lives in an aquatic environment, and only a few of the many serotypes are able to cause disease. When strains acquire the right genetic makeup – s... Read More

Bill to provide $1.1 billion Zika funding dies in Senate vote

WASHINGTON — The Senate on Tuesday blocked a $1.1 billion bill to combat the Zika virus, giving Congress just two weeks to try to reach a new deal before lawmakers leave for a seven-week recess in the midst of mosquito season and a growing public health crisis. Read More

A quick and easy new method to detect Wolbachia bacteria in intact Aedes mosquitoes

Aedes aegypti mosquitoes transmit dengue, chikungunya, and zika viruses. A study published in PLOS NTDs reports a new technique that could make one approach to mosquito control--using Wolbachia bacteria that reduce the mosquitos' ability to transmit viral pathogens--a whole lot easier and che... Read More

NIH-led effort uses implementation science to reduce mother-to-child HIV transmission

An emerging field, known as implementation science, may help reduce the nearly 150,000 instances of mother-to-child HIV transmissions that occur annually around the world, mostly in developing countries. A team of scientists and program managers, led by the National Institutes of Health, has bee... Read More

Thermos device quickly detects Zika for only $2

Engineers have developed a rapid, low-cost genetic test for Zika. The $2 device, about the size of a soda can, doesn’t require electricity or technical expertise and only needs a bit of saliva. Read More

MMP #14: A look at several microorganisms involved with electricity.

Host: Jeff Fox with special guests, Gemma Reguera and Geoffrey Gadd.

Gemma Reguera of Michigan State University in East Lansing and Geoffrey Gadd of the University of Dundee in Scotland talk with Jeff Fox about their efforts, to probe some of the electrical properties of materials pro... Read More

Boston subway system covered in microbes, but they're not harmful

As part of its Microbiology of the Built Environment initiative, the Alfred P. Sloan Foundation started funding projects a few years ago that touched on the interaction of microbiology with architecture, buildings or, in the case of Curtis Huttenhower, PhD, an associate professor of computationa... Read More

Cross-respiration breathes life into a periodontal pathogen

Microbiome research has revealed that there are good guy and bad guy bacteria living together in complex communities on our skin, in our mouths, throughout our guts and pretty much everywhere in between. But what do you call a good guy bacterium that is aiding and abetting a disease culprit?

... Read More

UMMS scientists use CRISPR to discover Zika and dengue weaknesses

Scientists at the University of Massachusetts Medical School (UMMS) have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. This work, led by Abraham Brass, MD, PhD, assistant professor in microbiology & physiological systems, reveals new lea... Read More

How a cold gets into cells

Cold viruses cause us irritation by penetrating into our cells and transporting their RNA into the cytoplasma of the infected cells. This is the only way they can multiply. The details of how the transfer of the RNA from within the virus occurs are difficult to study. However, a new method has b... Read More

Tracking how bacteria threaten newborns

For years, researchers have struggled to get a handle on Group B streptococcus (GBS), in the hopes of improving neonatal outcomes. GBS are a bacteria commonly found in the vagina, rectum, and urinary tract of women. In healthy women, the bacteria are commensal, simply living without causing dise... Read More

Cross-respiration Between Oral Bacteria Leads to Worse Infections

Washington, D.C.—June 28, 2016—Researchers determined that two bacterial species commonly found in the human mouth and in abscesses, cooperate to make the pathogenic bacterium, Aggregatibacter actinomycetemcomitans, more infectious. Key to the cooperation is that the harmless partner provides th... Read More

Researchers Identify New Strategy for Decreasing Neonatal Mortality

Researchers have discovered how the bacteria Group B streptococcus (GBS) avoids detection by the immune system during pregnancy. The findings, reported in the journal mBio, could lead to the development of new drugs and strategies for treating GBS infection, which is a leading cause of neonatal ... Read More

Small RNAs regulate Bacteroides nutrient use

Just like you and me, bacteria have ‘favorite’ foods – though in the case of bacteria, 'favorite' translates to those which are energetically favorable or most accessible. Different bacteria have different preferences, based on their environments and the neighboring microbes that compete for or ... Read More

Anthrax capsule vaccine completely protects monkeys from lethal inhalational anthrax

Vaccination with the anthrax capsule--a naturally occurring component of the bacterium that causes the disease--completely protected monkeys from lethal anthrax infection, according to a study published online this week in the journal VACCINE. These results indicate that anthrax capsule is a hig... Read More

Mount Sinai researchers track HIV in real time as it infects and spreads in living tissue

By watching brightly glowing HIV-infected immune cells move within mice, researchers at the Icahn School of Medicine at Mount Sinai have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles. These interactions allow HIV to spread ... Read More
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