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Liver damage in hepatitis C patients significantly underestimated, says Henry Ford study

DETROIT - The number of hepatitis C patients suffering from advanced liver damage may be grossly underestimated and underdiagnosed, according to a study led by researchers at Henry Ford Health System and the U.S. Centers for Disease Control and Prevention. Read More

Paper-based test can quickly diagnose Ebola in remote areas (video)

BOSTON, Aug. 18, 2015 -- When a fever strikes in a developing area, the immediate concern may be: Is it the common flu or something much worse that requires quarantine? To facilitate diagnosis in remote, low-resource settings, researchers have developed a paper-based device that changes color, d... Read More

Unlikely Element Turns up in Enzyme; Commercial Renewable Fuels Might Ultimately Result

Washington, DC – August 14, 2015 - Tungsten is exceptionally rare in biological systems. Thus, it came as a huge surprise to Michael Adams, PhD., and his collaborators when they discovered it in what appeared to be a novel enzyme in the hot spring-inhabiting bacterium, Caldicellulosiruptor besci... Read More

Ebola’s Lessons - How the WHO Mishandled the Crisis

In a biological sense, last year’s Ebola epidemic, which struck West Africa, spilled over into the United States and Europe, and has to date led to more than 27,000 infections and more than 11,000 deaths, was a great surprise.

Local health and political leaders did not know of the presence o... Read More

$7 million grant aids efforts to eliminate neglected tropical diseases

Researchers at Washington University School of Medicine in St. Louis have received a $7 million grant from the Bill & Melinda Gates Foundation aimed at eliminating river blindness and elephantiasis, two neglected tropical diseases that annually sicken millions. Read More

Biologist investigates how gene-swapping bacteria evade antibiotics

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More

BacterioFiles 225 - Implanting Internal Invader Immunity

This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!

(14.5 MB, 15.8 minutes)

Show notes: 
Read More

TWiV 350: Viral gene therapy with Katherine High

Host: Vincent Racaniello

Guest: Katherine A. High

Vincent speaks with Katherine High about her... Read More

Toxoplasma parasite's greedy appetite may be its downfall

Toxoplasma gondii is estimated to chronically infect nearly one-third of the world's population, causing the condition Toxoplasmosis. It is most commonly associated with handling cat feaces and is a particular threat to pregnant women and immune-compromised individuals, such as HIV/AIDS patients... Read More

Stanford researchers genetically engineer yeast to produce opioids

For thousands of years, people have used yeast to ferment wine, brew beer and leaven bread. Now researchers at Stanford have genetically engineered yeast to make painkilling medicines, a breakthrough that heralds a faster and potentially less expensive way to produce many different types of pla... Read More

Peptides Produced by Gut Bacteria Could Hinder the Development of Type 1 Diabetes

BOC Sciences-Studies have found that peptides produced by a certain type of gut bacteria can be used to prevent type 1 diabetes from deteriorating and the lack of such gut bacteria along with the peptides may be the reason for type 1 diabetes in newborn babies.

The study was conducted by a co... Read More

Chickenpox continues to decline in US thanks to vaccination

Since the chickenpox vaccine became available in the U.S. in 1995, there has been a large reduction in chickenpox cases. Hospitalizations and outpatient visits for chickenpox have continued their decline after a second dose of the vaccine was recommended to improve protection against the disease... Read More

Chickenpox vaccination does increase shingles cases, but mainly in young adults

Vaccinating one-year-olds against chickenpox could temporarily nearly double the incidence of shingles in the wider population, but in younger adults than previously thought. Read More

A collection of polioviruses

In midsummer 1986, five years after starting my poliovirus laboratory at Columbia University, I received a letter from Frederick L. Schaffer, a virologist at the University of California, Berkeley, asking if I would like to have his collection of poliovirus stocks. He was retiring and the sample... Read More

SIV shrugs off antibodies in vaccinated monkeys

New research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine only needs to stimulate moderate levels of antibodies that neutralize the virus. Read More

HIV grows despite treatment, study finds

HIV can continue to grow in patients who are thought to be responding well to treatment, according to research by the University of Liverpool. Read More

An Ebolavirus vaccine in Africa

An Ebolavirus vaccine has shown promising results in a clinical trial in Guinea. This vaccine has been in development since 2004 and was made possible by advances in basic virology of the past 40 years. Read More

Bacterial Enzyme is Found for a Medical Way of Smoking Cessation

BOC Sciences-There is a new species of bacteria found by scientists from The Scripps Research Institute (TSRI) for a kind of enzyme it produces that can be used as an interfering substance to achieve smoking cessation. This finding will be smokingof considerable significance for its effectivenes... Read More

Bacterial enzyme may help people quit smoking

Current smoking cessation aids fail in 80 to 90 percent of smokers. The idea behind this therapy would be to destroy nicotine before it reaches the brain—depriving a person of the “reward” of nicotine that can trigger relapse into smoking. Pseudomonas putida, a bacterium typically found in tobac... Read More

Traitors in our midst: Bacteria use toxins to turn our own bodies against us

COLUMBUS, Ohio - Researchers who have revealed a highly efficient way that bacteria use toxins to interrupt the immune response say that until now, the trickery of these toxins has been underappreciated in science. Read More
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