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Viral Switches Share a Shape

A hinge in the RNA genome of the virus that causes hepatitis C works like a switch that can be flipped to prevent it from replicating in infected cells. Scientists have discovered that this shape is shared by several other viruses—among them one that kills cancer cells.

That’s Seneca Valley v... Read More

Research shows mushroom extract, AHCC, helpful in treating HPV

A Japanese mushroom extract appears to be effective for the eradication of human papillomavirus (HPV), according to a pilot clinical trial at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

The results were presented at the 11th International Conference of ... Read More

Genome sequenced of enterovirus D68 circulating in St. Louis

Researchers at Washington University School of Medicine in St. Louis have sequenced the genome of enterovirus D68 sampled from patients treated at St. Louis Children’s Hospital. Nationwide, the virus has spread rapidly in recent months and caused severe respiratory illness in young children, wit... Read More

Of Planes, Microbes and Clocks

New research shows how disruption of human biological clock can have negative impact on human intestinal micobiome and in turn lead to metabolic dysfunctions such as weight gain and diabetes. Read More

TWiP 78: Eau de rodent

 


Vincent and Dickson discuss how malaria parasites induce odors in their rodent hosts that attract mosquitoes.


Hosts: Vincent Racaniello and  Read More

TWiP 78 letters


Meliani writes:


Dear Sir,


My research is focused on the biofilms formation, Motility (swarming and swiming ) and QS in fluorescent Pseudomonas (P. aeruginosa and P. fluorescens).


In laboratory a interaction had been with insect and bacteria metabo... Read More

Researchers identify DNA of algae virus in humans

The DNA of a virus once thought confined to the cells of algae may in fact invade the biological kingdom of mice and men, according to a new study from researchers at Johns Hopkins University in Baltimore and the University of Nebraska-Lincoln.

The researchers, whose paper appeared Oct. 27 in... Read More

How Cells Know Which Way To Go

Two new studies shed light on how cells sense and respond to chemical trails. Amoebas aren’t the only cells that crawl: Movement is crucial to development, wound healing and immune response in animals, not to mention cancer metastasis. In two new studies from Johns Hopkins, researchers answer lo... Read More

Using microscopic bugs to save the bees

For decades, honeybees have been battling a deadly disease that kills off their babies (larvae) and leads to hive collapse. It’s called American Foulbrood and its effects are so devastating and infectious, it often requires infected hives to be burned to the ground.

Treating Foulbrood is comp... Read More

GW Researcher Adapting Breakthrough Technologies to Combat Parasitic Worm Infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approx... Read More

Complex Life Owes Its Existence To Parasites?

Is complex life rare in the cosmos? The idea that it could be rests on the observation that the existence of life like us – with large, energy hungry, complicated cells – may be contingent on a number of very specific and unlikely factors in the history of the Earth. Added together they suggest ... Read More

Positive clinical results indicate vaccine candidate is highly efficacious against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. This repr... Read More

Team discovers how microbes build a powerful antibiotic

Researchers have made a breakthrough in understanding how a powerful antibiotic agent is made in nature. Their discovery solves a decades-old mystery, and opens up new avenues of research into thousands of similar molecules, many of which are likely to be medically useful.

Click "source" to r... Read More

Bacteria Allow Woodrats to Eat Poison

This article was first published in 2013 on the website for the Society of Integrative and Comparative Biology.

Many plants do not want to be eaten. They avoid this fate by producing deadly toxins and carcinogenic poisons, such as those associated with the aptly named poison ivy, poison sumac... Read More

Millions of Doses of Ebola Vaccine to Be Ready by End of 2015

The World Health Organization (WHO) announced plans on October 24 to produce millions of doses of two experimental Ebola vaccines by the end of 2015.

Hundreds of thousands of doses should be available to help affected countries before the end of June, the WHO said at the conclusion of a meeti... Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.


Host: Vincent Racaniello Read More

Mineralization of sand particles boosts microbial water filtration

Mineral coatings on sand particles actually encourage microbial activity in the rapid sand filters that are used to treat groundwater for drinking, according to a paper published ahead of print in Applied and Environmental Microbiology. These findings resoundingly refute, for the first time, the... Read More

A gut bacterium that attacks dengue and malaria pathogens and their mosquito vectors

Just like those of humans, insect guts are full of microbes, and the microbiota can influence the insect's ability to transmit diseases. A new study reports that a bacterium isolated from the gut of an Aedes mosquito can reduce infection of mosquitoes by malaria parasites and dengue virus. The b... Read More

Ebola’s evolutionary roots more ancient than previously thought, study finds

A new study is helping to rewrite Ebola’s family history.

The research shows that filoviruses — a family to which Ebola and its similarly lethal relative, Marburg, belong — are at least 16-23 million years old.

Filoviruses likely existed in the Miocene Epoch, and at that time, the evolutio... Read More

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