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Bacteria could restore uranium mining aquifers

Wyoming’s resurgent uranium industry could get a further boost from University of Wyoming scientists, whose research on post-mining environmental restoration is yielding promising results.

Research in UW laboratories has shown that stimulating growth of native bacteria could be a more effecti... Read More

How Probiotics Will Improve Your Skin

The more time I spend in the beauty industry, the more I believe that clear, good skin is more of an art than a science. Sure, it's science-based, but there's an endless list of the things that are bad (sun, dairy, gluten, oils) and only a few things that are good (vitamin D; dairy, unless you a... Read More

Origin of segmented RNA virus genomes

Segmented genomes abound in the RNA virus world. They are found in virus particles from different families, and can be double stranded (Reoviridae) or single stranded of (+) (Closteroviridae) or (-) (Orthomyxoviridae) polarity. Our recent discussion of the advantages of a segmented viral genome,... Read More

Mosquito-borne virus chikungunya worries CDC

A debilitating, mosquito-borne virus called chikungunya has made its way to North Carolina, health officials say. It's the state's first reported case of the virus.
The patient was likely infected in the Caribbean, according to the Forsyth County Department of Public Health. Chikungunya is prim... Read More

Terms of Biology: The Pan-Genome

A still somewhat unfamiliar term is floating around: the pan-genome. In 2005, Tettelin et al. coined the term along with genome analyses of eight Streptococcus agalactiae strains, and Merry introduced it to this blog, some time back already. Today, a keyword search in PubMed returns roughly 200 ... Read More

Bacteria Show Promise in Restoring Aquifers Used in Uranium Mining

Wyoming’s resurgent uranium industry could get a further boost from University of Wyoming scientists, whose research on post-mining environmental restoration is yielding extremely promising results.

Research in UW laboratories has shown that stimulating growth of native bacteria could be a mo... Read More

Bacteria found in squid raises concern about spread of antibiotic resistance, study finds

Researchers in Canada have discovered one of the deadliest kinds of antibiotic-resistant bacteria for the first time in a food product — raw squid — widening the potential exposure for consumers, according to a report published Wednesday by the U.S. Centers for Disease Control and Prevention.

... Read More

TWiP 73: I'm nibbling my way back to you

Vincent and Dickson discuss how nibbling of human cells by Entamoeba histolytica, a process called amoebic trogocytosis, contributes to cell killing and tissue invasion.


Hosts: Vincent Racaniello Read More

TWiP 73 letters

Robin writes:


Liquids


Liquids are capable of forming a gas-liquid interface: maintenance of the surface requires adequate pressure in the gas. Adequate in this instance means a gas pressure greater than the vaporisation pressure in the liquid. The gas pressure... Read More

A Key Step Toward a Safer Strep Vaccine

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, have identified the genes encoding a molecule that famously defines Group A Streptococcus (strep), a pathogenic bacterial species responsible for more than 700 million infection... Read More

Gum Disease Bacteria Selectively Disarm Immune System, Penn Study Finds

The human body is comprised of roughly 10 times more bacterial cells than human cells. In healthy people, these bacteria are typically harmless and often helpful, keeping disease-causing microbes at bay. But, when disturbances knock these bacterial populations out of balance, illnesses can arise... Read More

TB Dogma Upended: Even Uninfected Cells Trigger Immune Defenses

Experimenting with mice, infectious disease experts at NYU Langone Medical Center have found that immune system cells uninfected with the bacterium that causes tuberculosis trigger immune system T cells to fight the disease. The findings upend the long-held scientific belief that only cells, kno... Read More

Genes found in nature yield 1918-like virus with pandemic potential

An international team of researchers has shown that circulating avian influenza viruses contain all the genetic ingredients necessary to underpin the emergence of a virus similar to the deadly 1918 influenza virus.

Searching public databases, the researchers, led by Yoshihiro Kawaoka of the U... Read More

TWiM 80 Letters

Bob writes:


Dear TWIM hosts,


I enjoyed episode 76, "Genetic biopixels and a pathogenic sweet tooth". I really enjoyed hearing about the course that Dr. Schaechter teaches and in particular the work his students did in developing the biosensor. I would like to ... Read More

The Spotty History of Chicken Pox

For its extreme antiquity the virus that causes chicken pox, it has a surprising sparse documented history. The earliest clear reference to the virus is actually to an emergence of its latent form as shingles, also called zoster. The ancient Greeks called it zoster after word for girdle, while ... Read More

Penn Research Develops ‘Onion’ Vesicles for Drug Delivery

One of the defining features of cells is their membranes. Each cell’s repository of DNA and protein-making machinery must be kept stable and secure from invaders and toxins. Scientists have attempted to replicate these properties, but, despite decades of research, even the most basic membrane st... Read More

Malaria: Blood cells behaving badly

New insight into how malaria parasites perturb flow, turning infected cells into sticky capillary cloggers, may lead to new and better treatments. All the billions of flat, biconcave disks in our body known as red blood cells (or erythrocytes) make three basic, tumbling-treadmill-type motions wh... Read More

Tiny microbes = big dollars

Gold!! Gold in them thar microbes . . . Read More

Malaria-carrying mosquitoes wiped out in lab with genetic method that creates male-only offspring

Scientists have modified mosquitoes to produce sperm that will only create males, pioneering a fresh approach to eradicating malaria. Since 2000, increased prevention and control measures have reduced global malaria mortality rates by 42 per cent, but the disease remains a prevalent killer espec... Read More

Herpes infected humans before they were human

Researchers have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern humans -- H... Read More

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