A rare and improbable mutation in a protein encoded by an influenza virus renders the virus defenseless against the body's immune system. This University of Rochester Medical Center discovery could provide a new strategy for live influenza vaccines in the future.
A new approach to the live fl... Read More
For decades a deadly fungus has been slaughtering amphibians around the world, driving many to the brink of extinction or even beyond.
But now one frog’s recovery shows that, with a little luck and habitat preservation, some amphibians may be able to evolve resistance to the fungus.
In lab... Read More
A new study shows that when heat-susceptible bacteria living symbiotically in the guts of insects are exposed to increased temperatures, both the bacteria and the insect are negatively impacted and can die. The study, reported online this week in the journal mBio®, illustrates another way globa... Read More
Laboratory tests show that a cold-tolerant mosquito known as Culex quinquefasciatus can be infected with Zika virus in the laboratory. If confirmed in the field, it would be a troubling development, suggesting the virus would be more difficult to control, and might be able to spread far north of... Read More
A popular antibiotic called rifampicin, used to treat tuberculosis, leprosy, and Legionnaire’s disease, is becoming less effective as the bacteria that cause the diseases develop more resistance.
One of the mechanisms leading to rifampicin’s resistance is the action of the enzyme Rifampicin m... Read More
Ten years ago, Takema Fukatsu, PhD, prime senior researcher and leader, National Institute of Advanced Industrial Science and Technology (AIST) in Japan, was invited to Kyoto University as a symposium speaker of a meeting organized by Kenji Fujisaki, PhD, a researcher in the University's Graduat... Read More
A team of researchers from the United Kingdom has obtained the first complete genome sequence of Zika virus that was isolated from a semen sample. The research is published this week in Genome Announcements, a journal of the American Society for Microbiology.
The motivation for this investiga... Read More
Sharon and Scott join the TWiV team to talk about their work on dengue antibody-dependent enhancement of Zika virus infection, and identifying the virus in mosquitoes from Miami.
Chikungunya virus has caused two recent massive outbreaks sickening millions of people. Now a team of researchers has shown that several existing compounds have potent activity against the critical CHIKV protease enzyme. The research is published October 10 in Antimicrobial Agents and Chemothera... Read More
A new tool that uses a forest-like array of vertically-aligned carbon nanotubes that can be finely tuned to selectively trap viruses by their size can increase the detection threshold for viruses and speed the process of identifying newly-emerging viruses.
"Early detection is important becau... Read More
Microbes are excellent at adapting to stressful situations, which is part of the reason antibiotic resistance is a problem today. Constant exposure to antimicrobials such as triclosan have selected for resistant strains, rendering the compound ineffective. This is why the FDA recently banned t... Read More
Dengue fever infects 390 million people each year, and kills as many as 25,000, according to the World Health Organization.
The disease could soon see these numbers decline as the Philippines start administering the world's first dengue vaccine to high-risk children.
The historic drug took... Read More
A team of Chinese investigators has discovered a gene for resistance to β-lactamase antibiotics, in the pathogenic marine bacterium, Vibrio parahaemolyticus. The β-lactamase gene, blaVEB-2, has never before been found in V. parahaemolyticus, and in fact, has been found almost exclusively in non-... Read More
Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.
Hosts: Read More
A team of scientists has created a genetic map of all possible receptors the human immune system might generate—also known as the immunome.
The project involved a mind-boggling data set.
“If we were on a treasure hunt, where the cure to many illnesses is the buried treasure, then we’ve jus... Read More
The Zika virus is set to spread through Asia, the World Health Organization warned Monday, with hundreds of cases reported in Singapore and two Thai babies diagnosed with Zika-linked microcephaly.
The mosquito-borne virus has been detected in 70 countries worldwide including at least 19 count... Read More
Researchers from UPM have revealed how mold from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.
A team of researchers from Centre for Plant Biotechnology and Genomics (CBGP, UPM-INIA), has published the results on Alt a1 in an article release... Read More
Researchers say there are 3 main factors that explain why women are more represented in some STEM (science, technology, engineering, and mathematics) fields than others.
The most powerful one, they say, is a “masculine culture” that makes many women feel like they don’t belong.
“There is w... Read More
The gut microbiome has stolen the show when it comes to the recent explosion of research on the bacteria that thrive within us. But bacteria also live in a woman's breast tissue—and the mix of those microbes may have an equally important effect on health, according to a new study in Applied and ... Read More
Cells never forget to take out the trash. It has long been known that cells tag proteins for degradation by labelling them with ubiquitin, a signal described as "the molecular kiss of death". Tim Clausen's group at the Research Institute of Molecular Pathology (IMP) in Vienna identified an analo... Read More