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New 'gut bacteria' clinical study could help reduce side-effects of radiotherapy

Researchers will examine the role of gut bacteria in influencing the side-effects patients experience after radiotherapy, in the first clinical study of its type.

The study will be carried out by researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Tru... Read More

Rotavirus Activates Lymphocytes from Non-Obese Diabetic Mice by Triggering Toll-Like Receptor 7 Signaling and Interferon Production in Plasmacytoid Dendritic Cells

It has been proposed that rotavirus infection promotes the progression of genetically-predisposed children to type 1 diabetes, a chronic autoimmune disease marked by infiltration of activated lymphocytes into pancreatic islets. Non-obese diabetic (NOD) mice provide a model for the human disease.... Read More

The Way You’re Born Can Mess With the Microbes You Need to Survive

Throughout the animal kingdom, mothers transfer microbes to their young while giving birth. Different species of tadpoles acquire specific skin bacteria from mother frogs even though they all live in the same pond with the same bacterial background. Emerging chicken eggs get inoculated with micr... Read More

Former Research Students and Their Success Stories, Part I!

As an educator and researcher at a small liberal arts institution, my success is measured (to me) in watching former students from my classroom and laboratory go on to do great things after graduation. Here, I share some great information about (and by) a former student of mine, Franny Gilman, ... Read More

Book Review: 'The Amoeba in the Room' by Nicholas P. Money & 'Missing Microbes' by Martin J. Blaser

From the WSJ:

In 2004, the rebel geneticist Craig Venter took a sailing trip to Bermuda and, unable to resist doing a little research on the side, hauled up 50 gallons of the Sargasso Sea and began trawling it for DNA. It looked for all the world like cold, sterile saltwater, but Mr. Venter h... Read More

Progress in understanding immune response in severe schistosomiasis

A mechanism that may help explain the severe forms of schistosomiasis, or snail fever, has been discovered by researchers. Schistosomiasis is one of the most prevalent parasitic diseases in the world. The study in mice may also offer targets for intervention and amelioration of the disease. Alth... Read More

Oral Bacteria and Cancer

Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More

Ancient whodunit may be solved: The microbes did it!

Methane-producing microbes may be responsible for the largest mass extinction in Earth’s history.

Evidence left at the crime scene is abundant and global: Fossil remains show that sometime around 252 million years ago, about 90 percent of all species on Earth were suddenly wiped out — by far ... Read More

Fighting bacteria with weapons from fungi

In order to survive, organisms produce small molecules known as ‘primary metabolites’ which help it to grow, develop and reproduce. Examples include nucleic acid used to make DNA, amino acids to make proteins, and simple sugars. Once the organism is established it will often start to produce ‘se... Read More

Bacterial Gut Biome May Guide Colon Cancer Progression

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, re... Read More

Raw Oysters Spike U.S. Rise in Bacterial Infections

Raw oysters, so good with hot sauce, increasingly can carry something even more unsettling to the stomach: A bacteria linked to vomiting, diarrhea and pain.

Infections with vibrio, a saltwater-based bacteria that can pool in shellfish, jumped 75 percent last year from 2006-2008, the U.S. Cent... Read More

Dairy scientist targets heat-resistant microbes

Corralling desperados with names like bacillus and paenibacillus will require ingenuity and an arsenal of weapons. These outlaws aren't rustling cattle—they're making milk sour and cheese soft and crumbly.

For more than a century, milk has been heated to kill any bacteria or pathogens that ca... Read More

The pathogen detectives: sourcing the post-earthquake cholera outbreak in Haiti

Natural disasters such as earthquakes can have far-reaching effects beyond the damage caused on the day they occur. The 2010 earthquake in Haiti damaged the already limited sanitation systems leading to areas without adequate toilet and washing facilities; perfect for the spread of infection dis... Read More

Reprogrammed Bacteria Build Self-Healing ‘Living Materials’

How handy would it be if, instead of taking your broken circuit board to the Genius Bar (again), you could just prompt it to heal itself? That’s the futuristic possibility researchers have recently inched ever so slightly toward, with the development of hybrid “living materials” made from bacter... Read More

TWiV 281: The Salk legacy with Peter L. Salk



Host: Vincent Racaniello


Guest: Peter L. Salk


Vincent meets up with Peter L. Salk to talk about development of the fir... Read More

Immune cell ‘defenders’ could beat invading bacteria

An international team of scientists has identified the precise biochemical key that wakes up the body’s immune cells and sends them into action against invading bacteria and fungi.
The patented work, published in Nature today, provides the starting point to understanding our first line of defen... Read More

Researchers Identify Protein That Helps Control Common Viral Infection

Infectious disease specialists at the Johns Hopkins Children’s Center have identified a protein that regulates the body’s immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune sys... Read More

Six to Tango

One genome at a time can be exciting, but two even more so. I’m not entirely sure why this is, although it may explain our fascination with sex. And what if more than two entities were involved? What if the intimacy were not just between two individual organisms, but between a greater number of ... Read More

Biological Samples

ILSbio is the company of choice for research institutions, biotech organizations and pharma companies looking for high quality, documented biological samples to support their research. With a wide range of specimens types available including diseased tissue, FFPE, blood, and serum, collections c... Read More

The Oldest Gem Tells its Tale

Modern Earth is nothing like it was in its early days. Our planet was formed some 4.56 billion years ago when a giant stellar cloud collapsed on itself due its massive size and gravitational force. The explosion also generated the sun and many other planetary bodies, including those that would e... Read More

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