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Pseudomonas aeruginosa – the molecular tools of a bacterial survivor

The bacteria Pseudomonas aeruginosa can thrive in environments as different as the moist, warm tissue in our lungs, and the dry, nutrient-deprived surface of an office wall. Such adaptability makes it problematic in healthcare – where it causes infections in cases of cystic fibrosis, cancer, HIV... Read More

Zika likely to spread in Asia Pacific: WHO

The Zika virus is set to spread through Asia, the World Health Organization warned Monday, with hundreds of cases reported in Singapore and two Thai babies diagnosed with Zika-linked microcephaly.

The mosquito-borne virus has been detected in 70 countries worldwide including at least 19 count... Read More

Antibiotic history of a hospital bed may increase a patient’s risk of infection

If the previous occupant of a hospital bed received antibiotics, the next patient who uses that bed may be at higher risk for a severe form of infectious diarrhea, according to a new study.

Clostridium difficile (C. diff) diarrhea causes 27,000 deaths each year in the U.S. Hospital patients t... Read More

Using satellite imagery to improve vaccination coverage

Looking for population shifts on satellite images could be a way to deliver vaccines and prevent or control disease outbreaks, a new study finds.

The findings, published in Scientific Reports, are based on analysis of satellite images, vaccine records, and measles case reports.

The researc... Read More

NYT - I’m a Doctor. If I Drop Food on the Kitchen Floor, I Still Eat It.

Aaron E. Carroll, professor of pediatrics at Indiana University School of Medicine, discusses the five-second rule about dropping food on the floor and still eating it. He reminds us that we touch lots of dirty surfaces everyday, from cell phone screens to money and even the kitchen sink sponge.... Read More

Cyanophages: Maximizing the Photo– and Redirecting the –Synthesis

Daniel Haeusser, an Assistant Professor in the Biology De­part­ment of Canisius College in Buffalo, New York, discusses the misconception of assuming that photosynthesis exists as single process of strict coupling between energy conversion and carbohydrate production. Read More

BacterioFiles 271 - Dictyostelium Delivers DNA Deathtraps

This episode: Slime molds have special cells that capture and kill bacteria using traps made of DNA!

(11.2 MB, 12.25 minutes)

Show notes: 

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Professor, graduate student unravel mystery of bacteria's antibiotic resistance

A popular antibiotic called rifampicin, used to treat tuberculosis, leprosy, and Legionnaire’s disease, is becoming less effective as the bacteria that cause the diseases develop more resistance.

One of the mechanisms leading to rifampicin’s resistance is the action of the enzyme Rifampicin m... Read More

How cells take out the trash—phosphoarginine deciphered

Cells never forget to take out the trash. It has long been known that cells tag proteins for degradation by labelling them with ubiquitin, a signal described as "the molecular kiss of death". Tim Clausen's group at the Research Institute of Molecular Pathology (IMP) in Vienna identified an analo... Read More

Autophagy, Illustrated (infographic)

Earlier this week, Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for his work on the underlying mechanisms of autophagy—the process by which cells break down and recycle their own contents. How does autophagy work? Here are the basics, as drawn for the article “How ... Read More

TWiV 410: Hurricane Zika

Sharon and Scott join the TWiV team to talk about their work on dengue antibody-dependent enhancement of Zika virus infection, and identifying the virus in mosquitoes from Miami.

Hosts: Vince... Read More

A Citizen Microbiology project on the Built Environment

There is a growing popular and policy interest in the microbiome, and the possibilities of more nuanced or ‘probiotic’ ways of living with germs. To date however there has been limited public engagement with the science and technology of metagenomics. The project engages with the growing scienti... Read More

Staphylococcus aureus has a resistance strategy that thwarts certain antimicrobials

The natural presence of fatty acids in the human body leads to increased resistance of Staphylococcus aureus to a class of antimicrobials that target bacterial fatty acid biosynthesis. This discovery, based on research by INRA scientists in collaboration with with INSERM, Hôpital Cochin APHP, th... Read More

Antibacterial and antiinflammatory properties of bovine colostrum

Colostrum is a thick, sticky, yellowish mammary secretion that all mammals provide to their newborns during the first 24-48 hours after delivery.

It has been reported that constituents from BC are 100-fold to 1,000-fold more potent than human colostrum. This means that even human infants can ... Read More

New, carbon-nanotube tool for ultra-sensitive virus detection and identification

A new tool that uses a forest-like array of vertically-aligned carbon nanotubes that can be finely tuned to selectively trap viruses by their size can increase the detection threshold for viruses and speed the process of identifying newly-emerging viruses.

"Early detection is important becau... Read More

Evidence Mounting Zika Virus Causes Paralytic Disease

Researchers have discovered the strongest evidence yet linking the Zika virus to the paralytic illness Guillain-Barre syndrome. During the height of the viral epidemic the incidence of Guillain-Barre was 100 times the number of cases usually seen.

Guillain-Barre is a normally rare condition t... Read More

How the Zika Virus Could Make Its Way to North America

Laboratory tests show that a cold-tolerant mosquito known as Culex quinquefasciatus can be infected with Zika virus in the laboratory. If confirmed in the field, it would be a troubling development, suggesting the virus would be more difficult to control, and might be able to spread far north of... Read More

World's first dengue fever vaccine launched in the Philippines

Dengue fever infects 390 million people each year, and kills as many as 25,000, according to the World Health Organization.

The disease could soon see these numbers decline as the Philippines start administering the world's first dengue vaccine to high-risk children.

The historic drug took... Read More

TWiM #136: Diderms and then monoderms

The TWiM team discusses the importance of neutrophils in microbial infections, and evidence that ancient bacteria had two cell walls.

Hosts: Vincent Racaniello, El... Read More

Yeast fights viruses!

Humans have used Saccharomyces cerevisiae yeast in baking, brewing and winemaking for millennia. New research from the University of Idaho and the University of Colorado Boulder reveals another way that yeast species can help our species: by demonstrating how viruses interact with their hosts, a... Read More
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