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Vitamin A supplementation may cause the immune system to 'forget' past infections

Although vitamin A supplementation can have profound health benefits when someone is deficient, new evidence is emerging to show that vitamin A supplementation above and beyond normal levels may have negative health consequences. A new research report published in the July 2015 issue of the Jour... Read More

TWiP 92: Kleptohaemodeipnonism

Vincent, Dickson, and Daniel discuss how fluctuation in the price of guinea pig food could help transmission of the agent of Chagas disease, and present a new case study for your consumption.


Hosts:  Read More

Researchers identify cause of heart damage in sepsis patients

Researchers at the University of Liverpool's Institute of Infection and Global Health (IGH) have discovered a common cause of heart damage in patients with sepsis.

Sepsis is the most common cause of death in hospitalised critically ill people and affects up to 18 million people world-wide ann... Read More

BacterioFiles 221 - Co-culture Close Contact, Cats, and Cockerels

This episode: More distantly related bacteria can help each other grow (and produce lots of hydrogen) by temporarily fusing with each other!


(12.7 MB, 13.9 minutes)


Show notes: 
Read More

Genetic differences may help explain inconsistent effectiveness of anti-HIV drug

Research with human tissue and cells suggests that genetic variations, in addition to failure to comply with treatment regimens, may account for some failures of an anti-HIV drug to treat and prevent HIV infection. Read More

TWiM #107: The battle in your bladder

Vincent and Michael discuss the highly diverse microbiome of uncontacted Amerindians, and how the composition of human urine plays a role in the bat... Read More

TWiM #108: Vaccine in the time of cholera

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

Oxford Ebola vaccine study moves to next phase

Oxford University doctors and scientists are performing the second phase of clinical studies of an experimental Ebola vaccine regimen. The study is part of the EBOVAC2 project, a collaborative programme involving the University of Oxford, French Institute of Health and Medical Research (INSERM) ... Read More

TWiV 346: A double helical career

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler


Guest:&nb... Read More

TWiV 345: How a vaccine got the nod

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

BacterioFiles 220 - Coliforms Cooperate by Conduit

This episode: Bacteria can connect to each other with tiny tubes to exchange nutrients!


(10 MB, 10.9 minutes)


Show notes: 
News item/ Read More

Early HIV treatment improves survival in some patients with newly diagnosed TB

PITTSBURGH, July 9, 2015 - Starting anti-HIV treatment within two weeks of the diagnosis of tuberculosis, or TB, improved survival among patients with both infections who had very low immune-cell counts, according to an analysis by researchers at the University of Pittsburgh Graduate School of H... Read More

Better Chocolate with Microbes

For decades, researchers have worked to improve cacao fermentation by controlling the microbes involved. Now, to their surprise, a team of Belgian researchers has discovered that the same species of yeast used in production of beer, bread, and wine works particularly well in chocolate fermentati... Read More

Virus-carrying mosquitoes are more widespread than ever, and spreading

Scientists behind the first global distribution maps of two species of dengue and chikungunya-carrying mosquitoes warn they are spreading to new areas where they could cause disease. Read More

Towards an HIV vaccine

Neutralizing antibodies (Nabs) are immune proteins that recognize, bind to, and trigger the elimination of virus before it can establish a chronic infection. How to elicit a potent Nab response capable of protecting against different HIV subtypes and against different modes of infection is criti... Read More

TWiM 107 Letters

Jim writes:


Hi Vince,
For your interest in listening to physics, there is a podcast called The Titanium Physicists Podcast. They use a conversational format similar to what you use. They have a panel of experts and a guest who is not a physicist but who is accom... Read More

TWiV 344: Glaswegians go viral

Host: Vincent Racaniello


Guests: Ruth Jarrett Read More

Health-care providers a major contributor to problem of antibiotic overuse

SALT LAKE CITY - 10 percent of health care providers write an antibiotic prescription for nearly every patient (95 percent or more) who walks in with a cold, bronchitis or other acute respiratory infection (ARI), according to a new Centers for Disease Control and Prevention-supported study publi... Read More

B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More

Host genetics played a role in vaccine efficacy in the RV144 HIV vaccine trial

July 15, 2012 (SILVER SPRING, Md.) - New findings published today in the journal Science Translational Medicine show that host genetics played a role in protection against HIV infection in the landmark RV144 vaccine trial conducted in Thailand. Read More
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