The adapted virus that immunized hundreds of millions of people against smallpox has now been enlisted in the war on cancer. Vaccinia poxvirus joins a herpesvirus and a host of other pathogens on a growing list of engineered viruses entering late-stage human testing against cancer.
After a de... Read More
A team of molecular biologists and computer scientists at Stony Brook University have used a novel method to weaken (attenuate) influenza virus by way of designing hundreds of mutations to its genetic code to create an effective vaccine.
The research is an outgrowth of years of investigation ... Read More
Eminent Australian scientist Professor Frank Fenner, who helped to wipe out smallpox, predicts humans will probably be extinct within 100 years, because of overpopulation, environmental destruction and climate change.
Fenner, who is emeritus professor of microbiology at the Australian Nationa... Read More
The mucosal immune system, which stands like a military battalion protecting the nasal passages, intestinal lining, and other vulnerable surfaces of the human body, is often the first to tangle with microbial invaders. It’s also of considerable interest to researchers who hope to improve vaccin... Read More
In her column for the New York Times, Olivia Judson writes vividly and informatively on fungi, and on yeast in particular, pointing out some surprising similarities to human life, and why yeasts are thus so useful for research. Read More
The Human Genome Project, along with numerous parallel efforts to solve the DNA sequences of hundreds of animal, plant, fungal, and microbe genomes in the last few decades, has produced enormous amounts of genetic data with which researchers are struggling to keep pace. Knowing gene sequences, a... Read More
Batches of Mozzarella balls turned blue because of bacterial contamination during production in Germany, Italian prosecutors and health officials said Tuesday, after more than a ton of the suspect cheese was seized.
But the German maker was insisting that the problem was resolved a month ago.... Read More
You wash your hands before supper, and you irradiate your mammoths before public display. French customs requires the latter, so researchers plan to hit the world’s oldest baby mammoth with three days worth of gamma rays.
In July 2009, a hunter found the mammoth, now known as Khoma, partially... Read More
National Physical Laboratory is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.
In May 2010 the project team, comprising biotechnology experts from NPL, the University of Edinburgh and... Read More
Dust-choked mine shafts, crowded working conditions and stifling hostels where up to 16 miners share a room — all conspire to make mining a more important contributor to tuberculosis in Africa than had been realized, a new study finds.
Rates of the illness have doubled in Africa over the pas... Read More
During her time at Columbia, Poje has worked on filoviruses, a group of viruses that include Ebola and Marburg, two pathogens that can cause severe damage to the blood and organs of humans, frequently resulting in death. Yet for all their danger, scientists know relatively little about filovirus... Read More
Q. OVER THE YEARS, WHAT HAS BEEN THE DISCOVERY YOU ARE MOST PROUD OF?
A. We pioneered an unconventional approach to solving the genetic basis of human disease. In the past when geneticists were researching an inherited disease — cystic fibrosis, breast cancer —they would systematically study ... Read More
Each of us harbors a unique collection of bacteria, on our outsides and our insides. Now, scientists are finding that the bacteria you get at birth may depend on how you got here. Because babies born vaginally have a different set of microbes than those that arrive by Caesarean-section. The work... Read More
Sampling of pigeons captured on the streets of Madrid has revealed the bacterial pathogens they carry. Researchers writing in BioMed Central's open access journal Acta Veterinaria Scandinavica found two bugs that were highly prevalent in the bird population, Chlamydophila psittaci and Campylobac... Read More
Scientists have completed the most comprehensive comparative analysis to date of bacterial communities inhabiting the human nose and throat, which could provide new insights into why some individuals become colonized with pathogens while others do not. They release their findings today in mBio™... Read More
Historic and culturally important artifacts, like all materials, are vulnerable to microbial attack. Cultural Heritage Microbiology, a new text from ASM Press, offers a synthesis of important scientific articles describing microbial deterioration of cultural heritage materials and methods for ... Read More
When it comes to a research article, how many pages is enough? How many is too many? These are matters mBio has wrangled with over the last year, and after much deliberation we’ve come up with a policy for page limits: http://mbio.asm.org/site/misc/authors.xhtml.
But why should mBio set pa... Read More
Researchers from the National Institutes of Health have developed a more sensitive test for Lyme disease that may offer earlier detection and lower cost. The details are reported in the June 2010 issue of the journal Clinical and Vaccine Immunology. Read More
Bacteria in the mouth may offer probiotic potential against upper respiratory tract infections, say researchers from the Università degli Studi di Milano, Milan, Italy, and Tampere University of Technology, Tampere, Finland.
They detail their findings in the June 2010 issue of the journal App... Read More
Hong Kong researchers suggest a new theory for why swine flu infections turned out to be so mild. Prior exposure to seasonal influenza A, either infection or vaccination, may induce a cross-reactive immune response against the pandemic virus. They report their findings in the July 2010 issue o... Read More