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Evolutionary war between microorganisms affecting human health, IU biologist says

BLOOMINGTON, Ind. -- Health experts have warned for years that the overuse of antibiotics is creating "superbugs" able to resist drugs treating infection. Read More

Some vaccines support evolution of more-virulent viruses

Scientific experiments with the herpesvirus such as the one that causes Marek's disease in poultry have confirmed, for the first time, the highly controversial theory that some vaccines could allow more-virulent versions of a virus to survive, putting unvaccinated individuals at greater risk of ... Read More

Freshman Symbiosis Course and Jack Gilbert!

As my Fall semester approaches, I am reflecting on last Fall. I taught a freshman seminar course revolving around symbioses and parasitism, and was fortunate to have many well known scientists be willing to "virtually visit" my class! Here is my report from last year on the great Jack Gilbert.... Read More

Mining Marine Microbes for New Drugs

This slideshow outlines the work of WHOI scientists Tracy Mincer and Kristen Whalen in the quest to beat antibiotic resistance through bioprospecting in the ocean. Read More

A Green Thumb for Ocean Microbes

MIT-WHOI Graduate student Kristen Hunter-Cevera describes the challenges and obstacles involved with growing marine microbes (in her case, Synechococcus) in a laboratory setting, and outlines the value of her research in understanding marine biogeochemistry. Read More

Cystic Fibrosis Microorganisms Survive on Little to No Oxygen

Washington, DC – July 28, 2015 – Microbes contributing to cystic fibrosis (CF) are able to survive in saliva and mucus that is chemically heterogeneous, including significant portions that are largely devoid of oxygen, according to a study published this week in mBio®, the online open-access jou... Read More

Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak

Research presented at the 2015 AACC Annual Meeting & Clinical Lab Expo will expand on the studies that led to a fingerprick Ebola test becoming the first and only rapid diagnostic for this disease to receive approval from the World Health Organization (WHO). This test could prove vital to breaki... Read More

New smart drug targets and reduces site-specific inflammation

BEER-SHEVA, Israel...July 22, 2015 - Ben-Gurion University of the Negev (BGU) and University of Colorado researchers have developed a dynamic "smart" drug that targets inflammation in a site-specific manner and could enhance the body's natural ability to fight infection and reduce side effects. Read More

Transgenic pigs resistant to foot-and-mouth disease

Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short... Read More

Lingering lymphocytes lash out against Leishmania

Immune cells that hang around after parasitic skin infection help ward off secondary attack, according to a study in The Journal of Experimental Medicine. These skin squatters may prove to be the key to successful anti-parasite vaccines. Read More

Malaria's key to the liver uncovered

Scientists uncover a port of liver entry for malaria parasites in a report published in The Journal of Experimental Medicine. If these results hold up in humans, drugs that target this entry protein might help prevent the spread of disease. Read More

BacterioFiles 222 - Cells Store Solar Sparks

This episode: Bacteria engineered to produce liquid fuel can eat carbon dioxide and hydrogen from solar-powered water-splitting!


(11.2 MB, 12.25 minutes)


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TWiV 347: Rose rosette and squirrel roulette

Hosts: Vincent RacanielloAlan Dove, and Rich Condit


Vincent, Alan, and Rich discu... Read More

THESE YEAST CELLS SAY ‘HI’ AND OTHERS RESPOND

Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More

Why West Nile virus is more dangerous in the elderly

West Nile virus (WNV) is particularly dangerous in older people, who account for a large number of severe cases and deaths caused by the virus. WNV infection turns serious when the virus crosses the blood-brain-barrier and wreaks havoc among nerve cells in the brain. A study published on July 23... Read More

It takes a village... to ward off dangerous infections? New microbiome research suggests so

ANN ARBOR, Mich. -- Like a collection of ragtag villagers fighting off an invading army, the mix of bacteria that live in our guts may band together to keep dangerous infections from taking hold, new research suggests. Read More

Antiviral compound protects nonhuman primates against Marburg virus

An experimental drug that protected monkeys from the deadly Marburg virus appears to have potential for treating people who have been exposed to the virus, according to a study published in the July 23 edition of The New England Journal of Medicine. Marburg virus is closely related to Ebola viru... Read More

TWiM #108: Vaccine in the time of cholera

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 108 Letters

Nervous in San Diego writes:


Dear Professors of TWiM,
I was recently introduced to TWiM by a neighbor. For the last few weeks I have been listening to the backlog of TWiM podcasts, mainly while walking our dog. Regrettably, our dog is a lousy conversationalist. L... Read More

Health-care providers a major contributor to problem of antibiotic overuse

SALT LAKE CITY - 10 percent of health care providers write an antibiotic prescription for nearly every patient (95 percent or more) who walks in with a cold, bronchitis or other acute respiratory infection (ARI), according to a new Centers for Disease Control and Prevention-supported study publi... Read More
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