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HIV uses the immune system's own tools to suppress it

A Canadian research team at the IRCM in Montreal, led by molecular virologist Eric A. Cohen, PhD, made a significant discovery on how HIV escapes the body's antiviral responses. The team uncovered how an HIV viral protein known as Vpu tricks the immune system by using its own regulatory process ... Read More

Single dose Ebola vaccine is safe and effective in monkeys against outbreak strain

National Institutes of Health (NIH) scientists report that a single dose of an experimental Ebola virus (EBOV) vaccine completely protects cynomolgus macaques against the current EBOV outbreak strain, EBOV-Makona, when given at least seven days before exposure, and partially protects them if giv... Read More

Researchers develop world's most sensitive test to detect infectious disease, superbugs

Infectious diseases such as hepatitis C and some of the world's deadliest superbugs--C. difficile and MRSA among them--could soon be detected much earlier by a unique diagnostic test, designed to easily and quickly identify dangerous pathogens. Read More

Powerhouse in your mouth

According to the American Academy of Implant Dentistry, two in three Americans have one or more missing teeth. To deal with this issue, American dentists perform more than five million dental implants a year. About 1% to 15% of the patients receiving implants experience dental implant failure ... Read More

Why West Nile virus is more dangerous in the elderly

West Nile virus (WNV) is particularly dangerous in older people, who account for a large number of severe cases and deaths caused by the virus. WNV infection turns serious when the virus crosses the blood-brain-barrier and wreaks havoc among nerve cells in the brain. A study published on July 23... Read More

Crime-scene compound may be newest tool in fight against malaria

The compound that detectives spray at crime scenes to find trace amounts of blood may be used one day to kill the malaria parasite. Read More

New method to treat antibiotic resistant MRSA: Bacteriophages

MRSA is bad news. If you've never heard of it, here's what you need to know: It's pronounced MER-suh, it's a nasty bacterial infection and it can cause serious disease and death. Read More

Why do we still use Sabin poliovirus vaccine?

The Sabin infectious, attenuated poliovirus vaccines are known to cause vaccine-associated paralysis in a small number of recipients. In contrast, the Salk inactivated vaccine does not cause poliomyelitis. Why are the Sabin vaccines still used globally? The answer to this question requires a bri... Read More

HIV patients should be included in early clinical trials of anti-TB drugs

Amsterdam, The Netherlands: Tuberculosis is the number one cause of death in HIV-infected patients in Africa and a leading cause of death in this population worldwide, yet the majority of these patients are excluded from the early stages in the development of new, anti-tuberculosis drugs, accord... Read More

BacterioFiles 214 - Cable-Chlorophyte Coop Conducts Current

This episode: Cable bacteria and algae set up electric grid in sediments!

(6 MB, 6.5 minutes)

Show notes: 
Journal Paper

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TSRI & Janssen study makes major advance toward more effective, long-lasting flu vaccine

LA JOLLA, CA - August 24, 2015 - Scientists from The Scripps Research Institute (TSRI) and the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) have found a way to induce antibodies to fight a wide range of influenza subtypes--work that could one day eliminate the need for repeate... Read More

Statistical advances help unlock mysteries of the human microbiome

Advances in the field of statistics are helping to unlock the mysteries of the human microbiome--the vast collection of microorganisms living in and on the bodies of humans, said Katherine Pollard, a statistician and biome expert, during a session today at the 2015 Joint Statistical Meetings (JS... Read More

Synthetic DNA vaccine against MERS induces immunity in animal study

PHILADELPHIA - A novel synthetic DNA vaccine can, for the first time, induce protective immunity against the Middle East Respiratory Syndrome (MERS) coronavirus in animal species, reported researchers from the Perelman School of Medicine at the University of Pennsylvania. Read More

The sting in dengue's tail

In a new Science study, Duke-NUS Graduate Medical School Singapore (Duke-NUS) scientists have identified how small changes in dengue's viral genome can affect the virus' ability to manipulate human immune defences and spread more efficiently. This research is the first of its kind that examined ... Read More

Study finds state policies influence vaccination, disease outbreak rates

Athens, Ga. - Lax state vaccination laws contribute to lower immunization rates and increased outbreaks of preventable diseases--like whooping cough and measles--according to a new study from the University of Georgia. Read More

UV light robots cut c. diff transmissions by 25 percent on cancer patient floors

SAN DIEGO--Robots are capable of all sorts of tasks to help better treat cancer: They connect oncologists to patients remotely, make incisions, staple them shut, deliver "nano" therapies--and they clean rooms. New research from Penn Medicine infection control specialists found that ultraviolet (... Read More

Toilet waste provides knowledge about diseases' global transmission routes

Current international disease surveillance systems are mainly based on reports made by doctors after treatment of infected patients. As a consequence, disease-causing microorganisms and resistance bacteria have time to spread and make large population groups sick before they are detected. Read More

BacterioFiles 237 - Proving Protist Predation Parentage

This episode: Vampirovibrio chlorellavorus, a predatory bacterium that feeds on Chlorella algae, is currently lost from science, but its genome has been sequenced and interpreted anyway, to reveal a surprising family history!

(9.4 MB, 10.25 minutes)

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New smart drug targets and reduces site-specific inflammation

BEER-SHEVA, Israel...July 22, 2015 - Ben-Gurion University of the Negev (BGU) and University of Colorado researchers have developed a dynamic "smart" drug that targets inflammation in a site-specific manner and could enhance the body's natural ability to fight infection and reduce side effects. Read More

NYU research: Severe liver damage in mid/late-adulthood among PWID with chronic HCV

The Hepatitis C virus (HCV) infection is a chronic blood-borne viral infection that affects an estimated 160 million people, or 2-3% of the population world-wide. Alarmingly, chronic HCV infection accounts for one-quarter of the cases of cirrhosis and hepatocellular carcinoma (HCC). If HCV is le... Read More
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