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Bat SARS-like coronavirus: It’s not SARS 2.0!

A study on the potential of SARS-virus-like bat coronaviruses to cause human disease has reawakened the debate on the risks and benefits of engineering viruses. Let’s go over the science and then see if any of the criticisms have merit. Read More

New Drug for Lung Cancer can Improve the Survival Rate Greatly

BOC Sciences-Scientists have found a drug called nivolumab more effective for non-small cell lung cancer, as it increases the survival time while bring less side effects than the traditional drug used for non-small cell lung cancer. Read More

HIV cure research: NIH scientists create 2-headed protein to deplete HIV reservoir

Scientists at the National Institutes of Health (NIH) have created a protein that awakens resting immune cells infected with HIV and facilitates their destruction in laboratory studies. The protein potentially could contribute to a cure for HIV infection by helping deplete the reservoir of long-... Read More

Interrupting the transmission cycle: A protein required for dengue virus infection of mosquitoes

There is currently no approved specific treatment or vaccine for dengue fever, and an estimated 2 billion people are at risk for being bitten by Aedes mosquitoes and infected with the dengue virus (DENV). A study published on October 22nd in PLOS Pathogens introduces a candidate target for a tra... Read More

New Diversity for Lager Beers

Washington, DC – September 25, 2015 - Unlike ales, lager beers differ little in flavor. But now, by creating new crosses among the relevant yeasts, Kevin Verstrepen, PhD, Stijn Mertens, and their collaborators have opened up new horizons of taste. The research is published in the September 25 Ap... Read More

Link between small mammals and evolution of hepatitis A virus to humans discovered

Researchers at the University of North Carolina at Chapel Hill (UNC-Chapel Hill) are part of an international team led by the University of Bonn, Germany, who have found a link between the origin of hepatitis A virus (HAV) and small mammals. With the emergence of Ebola virus from bats and hantav... Read More

TWiV 374: Discordance in B

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

Tripped up by a bug: Infection may cause falls, especially in older people, study suggests

SAN DIEGO - People who end up in the emergency room because of a fall often are tripped up by an infection, rather than a loose throw rug or poor eyesight, suggests a study being presented at IDWeek 2015™. Read More

Fungus Causing Fatal Infections in Hospitalized Patients Has Unique Growth Patterns

Washington, DC – August 17, 2016 – The multidrug-resistant yeast Candida auris, which has caused fatal infections in some hospitalized patients, has at least two different growth patterns and some of its strains are as capable of causing disease as the most invasive type of yeast called Candida ... Read More

Microbes After Hours: This Week in Virology LIVE - Zika Virus

A special live episode of the popular science podcast This Week in Virology at the headquarters of the American Society for Microbiology.... Read More

Role of breast cell infection in flu transmission between mothers and breast-feeding ferrets

Influenza is known as an infectious respiratory disease, but a study published on October 8th in PLOS Pathogens suggests that infected cells in breast tissues could play a role in virus transmission from mothers to breast-feeding infants and vice versa using a ferret model. Read More

Infectious diseases bring millions of elderly to emergency departments each year

Investigators estimate that during 2012, there were more than 3.1 million emergency department visits for infectious diseases among elderly US adults. Read More

Tardigrade genome sequencing reveals unprecedented horizontal gene transfer

Tardigrades are small animals (~1.5 mm in length) renowned for their ability to survive in many extreme environments. From wikipedia "...they can withstand temperatures from just above absolute zero to well above the boiling point of water (100 °C), pressures about six times greater than those ... Read More

Hibernating bats mount a partial immune response against white nose fungus

White-nose syndrome (WNS), an invasive skin infection caused by the Pseudogymnoascus destructans (Pd) fungus has killed millions of bats since it was first seen in North America in 2007. A analysis of gene expression in hibernating bats infected with the destructive fungus published on October 1... Read More

Gerilizumab IL-6 is Put into Human Trial for Rheumatoid Arthritis

BOC Sciences-Recently, a biotechnology company announced that gerilizumab IL-6 as a drug for rheumatoid arthritis was under trial in healthy people. Once the safety is proved in human trial, gerilizumab will be a better alternative for rheumatoid arthritis both in effect and cost. Read More

Microbes After Hours: Understanding the Pathogenesis of the Emerging Zika Virus

Dr. Michael Diamond, 2016 Elizabeth O. King Lecturer, has worked for the past two decades investigating how viruses work, with a goal of defining basic principles of pathoge... Read More

Is brushing your teeth harming your gut microbiome?

In the 1960’s, the microbicide triclosan, was introduced in the United States, and soon after, human weight started to increase dramatically. For some time, researchers have wondered whether triclosan could have played a role in disrupting endocrine dysfunction and contributing to the obesity ep... Read More

Burkholderia multivorans evolves in bursts in the lungs of cystic fibrosis patients

Leonilde M. Moreira, PhD, has been studying the Burkholderia complex for 15 years. The bacteria, known for causing pneumonia or septicemia in some individuals, can survive for prolonged periods in moist environments. During the last 10 years, it has become one of the more predominant bacteria se... Read More

New Technique Could Prevent Biofilms on Catheters and Medical Implants

Washington, DC – October 30, 2015 – Biofilms—mats of bacteria similar to the plaque that grows on teeth—frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against b... Read More

Testing the evolution of resistance by experiment

One of the hallmarks of bad science writing is the claim that any research to do with bacteria will lead to new antibiotics. In this case, however, the scientists backed up their claim. They took bacteria notorious for nosocomial infections (Pseudomonas aeruginosa) and exposed them to a toxin, ... Read More
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