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TWiV 237: Paleovirology with Michael Emerman



Hosts: Vincent Racaniello and Rich Condit Read More

Haiti cholera mutations could lead to more severe disease

The cholera strain that transferred to Haiti in 2010 has multiple toxin gene mutations that may account for the severity of disease and is evolving to be more like an 1800s version of cholera, reports a new Northwestern Medicine study.

The strain, "altered El Tor," which emerged around 2000, ... Read More

'Chase and Run' Cell Movement Mechanism Explains Process of Metastasis

A mechanism that cells use to group together and move around the body -- called 'chase and run' -- has been described for the first time by scientists at UCL. Published in Nature Cell Biology, the new study focuses on the process that occurs when cancer cells interact with healthy cells in order... Read More

Urgent search for flu source

Researchers suspect H7N9 virus is in bird markets as human cases rise rapidly. Virologists know its name: H7N9. What they don’t yet know is whether this novel avian influenza virus — first reported in humans in China less than two weeks ago — will rapidly fizzle out, become established in animal... Read More

Microbes or Not, Parasites All

Parasites pose a problem for the semantically-oriented microbiologist. There is no question that unicellular parasites such as Giardia, Plasmodium, or Toxoplasma are microbes, thus we can appropriate them with impunity. But what about parasitic worms? They are clearly not microscopic* and are ta... Read More

Father-Son Duo Reinvent Drug Testing With ‘Digital Lab Rats’

In 2008, François-Henri Boissel was leading a charmed life. He was a young, successful investment banker working in Tokyo, Japan. And then the market crashed.

He thought of sticking it out, waiting until things improved, but then he remembered a conversation he’d had with his father, Jean-Pie... Read More

Secrets of bacterial slime revealed

Newcastle University scientists have revealed the mechanism that causes a slime to form, making bacteria hard to shift and resistant to antibiotics.
When under threat, some bacteria can shield themselves in a slimy protective layer, known as a biofilm. It is made up of communities of bacteria h... Read More

Vampire Bat Bites Help Shield Peruvians from Rabies

Rabies has been thought of as virtually 100-percent fatal unless treated immediately, but new research shows that a small number of isolated Peruvians have natural immunity from the animal-transmitted disease.

Researchers at the Centers for Disease Control and Prevention found that one in 15 ... Read More

Human Infection With Influenza A(H7N9) in China

On 3 April 2013, the China Health and Family Planning Commission notified WHO of an additional four cases of human infection with influenza A(H7N9). The four patients are from Jiangsu province in eastern China. There is no link between the cases.

The patients include a 45-year-old woman with ... Read More

Read any ASM Press eBook Free for a Week!

The American Society for Microbiology is celebrating Read an eBook Week* from April 1st to April 5th, 2013. During this time, they are offering full access to many of their titles and you can read your favorite eBooks for free at the ASM Press eBookstore. (Click "source" above for the link.)

... Read More

4-year-old bird flu 'carrier' worries China

Doctors say the discovery of a 4-year-old carrier of the H7N9 bird flu virus who shows no symptoms of the potentially lethal virus is a worrying development that could make the spread of the infection more difficult to monitor.

The Beijing Municipal Health Bureau said the boy was detected fro... Read More

No sign of human transmission in new bird flu appearance: WHO

The World Health Organization says no evidence has emerged to show that a type of bird flu which has killed two Chinese men can be transmitted between people.

Two men in Shanghai, aged 87 and 27, fell sick in late February. A woman in Anhui province also contracted the virus in early March an... Read More

Rapid emergence and antigenic diversification of the norovirus 2012 Sydney variant in Denmark, October to December, 2012

The norovirus (NoV) season in Denmark in late 2012 was characterised by an increase in the number of NoV infections caused mainly by the 2012 Sydney variant, but also by the 2009 New Orleans variant. Analysis of approximately 85% of the capsid gene from 10 Sydney 2012 and 9 New Orleans 2009 isol... Read More

Next to You on the Subway

Norman R. Pace, a microbiologist at the University of Colorado Boulder, pioneered the use of DNA to study microbes. He has searched for extremophiles (organisms that can exist in extreme environments) in the hot springs of Yellowstone National Park and once descended in the submersible Alvin to ... Read More

Symbiotic bacteria program daily rhythms in squid using light and chemicals

Glowing bacteria inside squids use light and chemical signals to control circadian-like rhythms in the animals, according to a study to be published on April 2 in mBio®, the online open-access journal of the American Society for Microbiology. The Hawaiian bobtail squid, Euprymna scolopes, houses... Read More

Newfound gene may help bacteria survive in extreme environments

In the days following the 2010 Deepwater Horizon oil spill, methane-eating bacteria bloomed in the Gulf of Mexico, feasting on the methane that gushed, along with oil, from the damaged well. The sudden influx of microbes was a scientific curiosity: Prior to the oil spill, scientists had observed... Read More

2 dead in China from unusual bird flu strain

Hong Kong (CNN) -- Two people in China have died and another remains critical after falling ill with a strain of bird flu not detected before in humans, the official Chinese news agency Xinhua reported. Both of those who died, men aged 27 and 87, lived in Shanghai, while a 35-year-old woman in C... Read More

New instrument will quickly detect botulinum, ricin, other biothreat agents

Researchers at Sandia National Laboratories are developing a medical instrument that will be able to quickly detect a suite of biothreat agents, including anthrax, ricin, botulinum, shiga and SEB toxin.

The device, once developed, approved by the Food and Drug Administration and commercialize... Read More

Platelets Help Tackle Bacteria

The cell fragments play a role in the body’s first line of defense against bacterial infection, helping white blood cells grab blood-borne bacteria in the liver. Platelets may contribute to protection against bacterial infection, according to new research published today (June 16) in Nature Immu... Read More

Scientists reconstruct the genome of medieval strains of the pathogen responsible for leprosy

Why was there a sudden drop in the incidence of leprosy at the end of the Middle Ages? To answer this question, biologists and archeologists reconstructed the genomes of medieval strains of the pathogen responsible for the disease, which they exhumed from centuries old human graves. Their result... Read More

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