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'Rhythm' of protein folding encoded in RNA, biologists find

Multiple RNA sequences can code for the same amino acid, but differences in their respective "optimality" slow or accelerate protein translation. Stanford biologists find optimal and non-optimal codons are consistently associated with specific protein structures, suggesting that they influence t... Read More

Virus Victors: People Who Control HIV (podcast)

Bruce Walker, Professor of Medicine at Harvard Medical School and Director of the Ragon Institute of Massachusetts General Hospital, MIT and Harvard, talks about his article in the July issue of Scientific American magazine called Controlling HIV, about rare individuals who never develop AIDS af... Read More

Be curious

During my visit to the University of Vermont today I had lunch with seven talented Microbiology Ph.D. students. One of them asked me what was an important quality to have for achieving success in science. I said without hesitation, ‘Be curious’. It’s the answer I always give. Being curious is th... Read More

TWiV 233: We're surrounded



Hosts: Vincent Racaniello, Rich Condit, Read More

Research Advances Therapy to Protect Against Dengue Virus

Nearly half of the world's population is at risk of infection by the dengue virus, yet there is no specific treatment for the disease. Now a therapy to protect people from the virus could finally be a step closer, thanks to a team at MIT.

In a paper published today in the Proceedings of the N... Read More

Leaf-cutting ants prefer low-fungi leaves

In the February issue of New Phytologist, Tulane University biologists examine why leaf-cutting ants target some plants and avoid others, concluding that high levels of friendly fungi in the leaves of some plants protect them from destruction by ants.

Leaf-cutting ants are major defoliators, ... Read More

Wrinkly coating can shimmy off bacteria

Applied to the hull of a ship like paint, a new material could shake off scum by moving in response to an electric current.

Bacterial buildup on ships increases drag and reduces the energy efficiency of the vessel, as well as blocking or clogging undersea sensors.

The material works by phy... Read More

IDRI and Medicago Report Positive Results for Phase I Clinical Trial for an H5N1 Vaccine

IDRI (Infectious Disease Research Institute), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc. (TSX: MDG; OTCQX: MDCGF), a biopharmaceutical company focused on developing highly effective an... Read More

Epidemiological Endgame: Is Polio on the Brink of Eradication?

Despite the pointless political assassinations of vaccine workers or the police officers who guard them in a few deeply troubled areas, enough progress has been made against polio in the past year that health experts are now planning for the grand finale—its complete eradication by 2018. The off... Read More

‘Zoomable’ Map of Poplar Proteins Offers New View of Bioenergy Crop

Researchers seeking to improve production of ethanol from woody crops have a new resource in the form of an extensive molecular map of poplar tree proteins, published by a team from the Department of Energy's Oak Ridge National Laboratory.

Populus, a fast-growing perennial tree, holds potenti... Read More

From blank round to a potently active substance?

A long-forgotten candidate for antiviral therapy is undergoing a renaissance: Since the 1970s, the small molecule CMA has been considered a potent agent against viral infections, yet it was never approved for clinical use. Scientists at the Bonn University Hospital have now deciphered how the mo... Read More

Resistance to Visceral Leishmaniasis: New Mechanisms Involved

Researchers from CNRS, Université Toulouse III -- Paul Sabatier and IRD have elucidated new molecular mechanisms involved in resistance to visceral leishmaniasis, a serious parasitic infection. They have shown that dectin-1 and mannose receptors participate in the protection against the parasite... Read More

Food Laboratory Accuracy Remains A Concern

Food microbiology laboratories continue to submit false negative results and false positive results on a routine basis. A retrospective study of nearly 40,000 proficiency test results over the past 14 years, presented today at the 113th General Meeting of the American Society for Microbiology, ... Read More

American Academy of Microbiology releases resistance report

What do cancer cells, weeds, and pathogens have in common? They all evolve resistance to the treatments that are supposed to eliminate them. However, researchers developing the next generation of antibiotics, herbicides, and anti-cancer therapeutics rarely come together to explore the common evo... Read More

Life on a flower is tough: stress-tolerant bacteria part of ecosystem on apple blossoms

It may well be snowing where you live, but if you're in the Northern Hemisphere, spring isn't far off. Spring means flowers. And what is a flower to a microbiologist? It's a niche.
Yes, flowers are a microbial habitat like any other, and though they start out with few microbial members, these ... Read More

Study finds maternal diet may predict respiratory syncytial virus severity

An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy.

Fernando Polack, M.D., Cesar Milstein Professor of Pediatrics, is lead author of an article in the American Journal of Respiratory and Critical Care Medicine... Read More

Science News For Kids: Deadly new virus emerges

Over the past year, a viral infection has infected 15 people — killing nine. All lived in the Middle East or Britain. The novel germ doe not yet have a formal name. It causes pneumonia, a type of severe lung infection. On Feb. 27, scientists from around the world met in Washington, D.C., to shar... Read More

New hope in fight against multi-resistant germs (press release)

An increasing number of bacteria is evolving antibiotic resistance. Much-feared representatives of this steadily growing group include Staphylococci strains. At this point, multi-resistant forms of the bacterium Staphylococcus aureus - the "hospital germ" known commonly by its acronym, MRSA - ca... Read More

Sourdough Bacteria Pump Out Mold Killers

As many San Franciscans have noticed, sourdough bread stays fresher longer than the regular stuff. Sourdough’s extended freshness is due to extra fermentation that traps more moisture in the dough. But now we know that sourdough’s longevity is also because it can ward off mold. Because bacteria ... Read More

Studio 360 - Reconstructing Viruses (podcast)

Vincent Racaniello of Columbia University did groundbreaking research on reconstructing the DNA of viruses (sort of like microbial Jurassic Park). The method was used to re-create the spectacularly lethal influenza behind the 1918 Spanish flu epidemic, which killed between 50 and 100 million peo... Read More

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