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Despite Superbug Crisis, Progress in Antibiotic Development 'Alarmingly Elusive'

Despite the desperate need for new antibiotics to combat increasingly deadly resistant bacteria, the U.S. Food and Drug Administration (FDA) has approved only one new systemic antibiotic since the Infectious Diseases Society of America (IDSA) launched its 10 x ’20 Initiative in 2010 — and that d... Read More

A 'neurosteroid' found to prevent brain injury caused by HIV/AIDS (press release)

New research in The FASEB Journal suggests that a network of steroid molecules found in the brain is disrupted during HIV infection, and treatment with the steroid DHEA-S prevents brain damage.

A team of scientists from Canada, Thailand and Morocco have found that DHEA-S may prevent neurocogn... Read More

H5N1 viral-engineering dangers will not go away

Governments, funders and regulatory authorities must urgently address the risks posed by gain-of-function research, says Simon Wain-Hobson. Barely two months after a small group of influenza virologists lifted a moratorium on work to make the H5N1 avian flu virus as transmissible between humans... Read More

Bacteria organize according to "rich-get-richer" principle

Bacteria on a surface wander around and often organize into highly resilient communities known as biofilms. It turns out that they organize in a rich-get-richer pattern similar to the distribution of wealth in the U.S. economy, according to a new study by researchers at University of California,... Read More

China Bird-Flu Deaths Rise to 13 as H7N9 Virus Spreads

Beijing confirmed that a 7-year-old girl has H7N9 avian influenza and Henan province reported its first two cases, opening a new front in the spread of the virus in the world’s most populous nation. Shanghai said today two people infected with the strain of bird flu died, taking the country’s de... Read More

Cellular alchemy caught in action

One of the most critical biological advances in the past decade was the discovery that the introduction of four simple genetic factors can turn a fully mature adult cell back into an embryonic-like state, a process called reprogramming.

Cllick "source" to read more and view video. Read More

Biodiversity doesn’t lower disease risk for people

A new analysis pokes holes in a widely accepted theory that connects biodiversity abundance with a reduced disease risk for people. More than three quarters of new, emerging, or re-emerging human diseases are caused by pathogens from animals. The dilution effect—considered to be one of the most... Read More

Irritable Bowel Linked To Gut Bacteria, Definitively

A new study of Greek patients shows that overgrowth of bacteria in the gut is definitively linked to irritable bowel syndrome (IBS). It is the first to use the "gold standard" method of examining gut bacterial cultures to connect bacteria to the cause of a disease that affects some 30 million Am... Read More

Research deciphers HIV attack plan

LOS ALAMOS, N. M., March 29, 2013—A new study by Los Alamos National Laboratory and University of Pennsylvania scientists defines previously unknown properties of transmitted HIV-1, the virus that causes AIDS. The viruses that successfully pass from a chronically infected person to a new individ... Read More

Scripps Research Institute Scientists Find Interferon, One of the Body’s Own Proteins, Induces Persistent Viral Infection

Scientists at The Scripps Research Institute (TSRI) have made a counterintuitive finding that may lead to new ways to clear persistent infection that is the hallmark of such diseases as AIDS, hepatitis B and hepatitis C.

The study, reported in the April 12, 2013 issue of the journal Science, ... Read More

France confirms 1st case of new SARS-related virus

A 65-year-old Frenchman is hospitalized after contracting France's first case of a deadly new respiratory virus related to SARS, and French health authorities said Wednesday they are trying to find anyone who might have been in contact with him to prevent it from spreading.

It's unclear how o... Read More

Garlic Constituent Blocks Biofilm Formation, Could Benefit Cystic Fibrosis Patients and Others

E Pluribus Unum, the de facto motto of the United States, could just as well apply to biofilm-forming bacteria. Bacterial biofilms are far more resistant than individual bacteria to the armories of antibiotics we have devised to combat them. Now Tim Holm Jakobsen and Michael Givskov of the Univ... Read More

H7N9 Bird Flu: Could Animals Other than Birds Harbor the Virus?

Researchers have more questions than answers about the latest bird flu circulating in China, including whether birds are the only reservoir for the virus.

The World Health Organization (WHO) reports that 17 people in China have died of H7N9 infection, and there is no evidence of person-to-per... Read More

Mars Was a Suitable Environment for Life

The first analysis of powder samples drilled out from the inside of once water-soaked rock shows Mars was a suitable place for microbial life to evolve, scientists with NASA’s Mars rover Curiosity mission said Tuesday.

Among the chemicals discovered inside the rock, called “John Klein,” were ... Read More

China readies to fight new bird flu; Japan, Hong Kong on guard

China said it was mobilizing resources nationwide to combat a new strain of deadly bird flu that has killed four people, as Japan and Hong Kong stepped up vigilance against the virus and Vietnam banned imports of Chinese poultry.

The H7N9 bird flu strain does not appear to be transmitted fro... Read More

Hospitals see surge of superbug-fighting products

They sweep. They swab. They sterilize. And still the germs persist.

In U.S. hospitals, an estimated 1 in 20 patients pick up infections they didn't have when they arrived, some caused by dangerous 'superbugs' that are hard to treat.

The rise of these superbugs, along with increased pressur... Read More

Genes define the interaction of social amoeba and bacteria

Amoeba eat bacteria and other human pathogens, engulfing and destroying them – or being destroyed by them, but how these single-cell organisms distinguish and respond successfully to different bacterial classes has been largely unexplained.

In a report in the journal Current Biology, research... Read More

High steaks

Those who take part in clinical trials often have to do nasty things, from taking new drugs to forgoing sleep. Participants in a trial organised by Stanley Hazen of the Cleveland Clinic, in Ohio, had a decidedly easier task: eating steak. After reading Dr Hazen’s conclusions, though, they may be... Read More

D.C. Rolls Out New HIV Test That Could Increase Chance of Cure

The recent news about a baby in Mississippi and 14 French adults said to have been "cured" of HIV infection has fueled excitement that the end of HIV/AIDS could be within sight. Both situations raise more questions than they currently answer.

Although no one can say we now have "the" cure for... Read More

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