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Structure of Zika virus determined

A near-atomic level map of Zika virus shows its structure to be largely similar to that of dengue virus and other flaviviruses, but with a notable difference in one key surface protein, report scientists funded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the Nat... Read More

Global E. coli Testing Market to be Worth US$2.1 bn by 2022, Driven by Rising Demand for Enzyme Substrate Kits

Escherichia coli (E.coli) is a Gram negative rod-shaped bacteria commonly found in intestines of warm blooded animals. Majority of the E.coli strains are harmless, however certain strains are known to cause serious medical complications.The rising number of supportive initiatives from government... Read More

Using citizen science to engage students

Scientists and science educators now recognize the value in explaining what fields don’t understand, in addition to facts supported by years of experimental data. Citizen science projects, which emphasize accessibility of scientific technologies and methods for everyone, allow people without yea... Read More

RESURRECTED DRUG MAY OFFER A WAY TO FIGHT ZIKA, EBOLA

Viruses have proven to be wily foes. Attempts to fend off viruses that cause the common cold or flu have failed, and new viral outbreaks such as dengue, Ebola, or Zika continue to elude drugs.

Given these challenges, scientists are tackling the problem from a different angle. The want to boos... Read More

An ancient killer: Ancestral malarial organisms traced to age of dinosaurs

CORVALLIS, Ore. - A new analysis of the prehistoric origin of malaria suggests that it evolved in insects at least 100 million years ago, and the first vertebrate hosts of this disease were probably reptiles, which at that time would have included the dinosaurs. Read More

Nonpathogenic viruses transferred during fecal transplants

Fecal transplants are increasingly being used for refractory Clostridium difficile and other gastrointestinal disorders. While fecal donors are screened for various infectious diseases, it is unclear whether viruses can in fact be transmitted during fecal transplants. Now a new study shows that ... Read More

Global Pain Management Therapeutics Market to Exhibit -5.50% CAGR from 2012 to 2018 owing to Patent Expiry of Blockbuster Drugs

Chronic pain is a very common health concern in all regions across the globe. Due to the ill effects of chronic pain, there has been an increase in the demand for pain management therapeutics. The global pain management therapeutics market offers many methods or therapies of pain management such... Read More

BacterioFiles 245 - Plant Prokaryotes Produce Protective Plaques

This episode: Bacteria around rice roots help protect plants from arsenic toxicity!


(10.1 MB, 11 minutes)


Show notes: 
News item/ Read More

TWiP 106: Trematode stormtroopers in snail wars

The TWiP triumvirate solves the case of the Missionary in Kenya, and review the finding of a soldier caste in flatworms that parasitize snails.


Hosts: Vincent Racaniello Read More

A biofilm model that accounts for cell aggregates

Whether you’ve Google-searched “biofilm” to learn more yourself, taken courses covering the subject, or are deeply embedded in biofilm-related research, you’ve probably encountered a model similar to the one below, which represents biofilm maturation. In the current model, a biofilm begins with ... Read More

Top secret, viruses with RNA genomes!

Today it is well known that viruses may contain DNA (poxvirus, mimivirus) or RNA (influenza virus, Zika virus), but for many years it was thought that genomes were only made of DNA. The surprise at finding only RNA in a virus is plainly evident in a 1953 letter from Harriett Ephrussi-Taylor to J... Read More

People with rage disorder twice as likely to have latent toxoplasmosis parasite infection

Individuals with a psychiatric disorder involving recurrent bouts of extreme, impulsive anger--road rage, for example--are more than twice as likely to have been exposed to a common parasite than healthy individuals with no psychiatric diagnosis. Read More

Curcumin may help overcome drug-resistant tuberculosis

New research indicates that curcumin--a substance in turmeric that is best known as one of the main components of curry powder--may help fight drug-resistant tuberculosis. In Asia, turmeric is used to treat many health conditions and it has anti-inflammatory, antioxidant, and perhaps even antica... Read More

Shiga toxin: no preassembly required

The molecular order of events is important in virulence, and a new paper published in the Journal of Bacteriology looks at the order of events necessary for bacterial toxin delivery to a host cell. Specifically, the authors looked at the assembly of Shiga toxin, produced by Shigella dysenteriae ... Read More

Simulation study shows that pandemic swine flu had a minor impact in Finland

Researchers have used modeling to estimate the true impact of infectious diseases, such as swine flu, when underreporting can mean the surveillance from time of the pandemic can miss the vast majority of infections that occur in the population. Read More

Research shows potential for emergence of new Ebola virus that causes disease in humans

New research at the University of Kent has highlighted the potential for the emergence of a new form of Ebolavirus.

A team from the University's School of Biosciences examined the differences between Ebolaviruses that cause severe disease in humans and the Reston virus that does not. Read More

TWiM #124: Fungal pirates

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michael, and Michele reveal how a fungal protease blunts the innate immune response and promotes pathogenicity. 


Read More

Biological factors predict which viruses will cause human epidemics

The identification of biological factors that predict which viruses are most likely to spread among humans could help prevent and contain outbreaks, a study in today's Proceedings of the National Academy of Sciences reports. Read More

Temple scientists eliminate HIV-1 from genome of human T-Cells

(Philadelphia, PA) - A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS. In a study published online this month in the Nature journal, ... Read More

The Healthcare Industry’s Rising Need for Sophisticated Medical Cameras and Microscopes

Restorative cameras and magnifying instruments are utilized for an extensive variety of medicinal applications. Increment in the quantity of surgeries performed drives interest for surgical magnifying lens. Correspondingly, ascend in the predominance of ailments, for example, growth expands inte... Read More
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