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HOW MAPLE SYRUP COULD IMPROVE ANTIBIOTICS

A concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics, according to laboratory experiments.

The findings, which will appear in the journal Applied and Environmental Microbiology, suggest that combining maple syrup extract with common antibiotics ... Read More

Unearthing new antivirals

SAN DIEGO (April 14, 2015) -- A team of biologists from San Diego State University has developed a platform for identifying drugs that could prove to be effective against a variety of viral diseases. In a pair of recent articles in the Journal of Biomolecular Screening and the Journal of Visuali... Read More

Paper and Phones Could Soon Diagnose Ebola and HIV for $1

Diseases such as HIV and Ebola are on the verge of being diagnosed almost instantly using paper-based technology costing less than $1. Read More

Shape-shifting molecule tricks viruses into mutating themselves to death

A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material. The findings from the University of Chicago and the Massachusetts Institute of Technology could bolster efforts ... Read More

How a bacterial cell recognizes its own DNA

It may come as a bit of a surprise to learn that bacteria have an immune system - in their case to fight off invasive viruses called phages. And like any immune system - from single-celled to human - the first challenge of the bacterial immune system is to detect the difference between "foreign"... Read More

Six questions about HIV/AIDS that deserve more attention

As HIV investigators work to control and eradicate the virus worldwide, certain myths or misconceptions about the disease have been embraced, whereas other concepts with merit have been left relatively unexplored, argues American HIV/AIDS researcher Jay Levy, MD, in a commentary publishing April... Read More

To fight nasty digestive bugs, scientists set out to build a better gut -- using stem cells

Researchers at the University of Michigan are studying the ecology of microbes in the GI tract in hopes of developing novel diagnostic tests and effective treatments for intestinal disease. How are they studying this? By creating tiny gut ecosystems! Using undifferentiated stem cells, the inv... Read More

microbe subway map

Explore an awesome map of microbes on the NY subways for yourself! Read More

Sierra Leone: Ebola Trial Begins

An Ebola vaccine candidate that has been successful in non-human primates is being tested on volunteers in Sierra Leone this month, where two new cases were reported as of Monday. Read More

HOW ZINC ‘JAMS UP’ THESE DRUG-RESISTANT MICROBES

New research from the University of Queensland has shown how zinc "tricks" an essentialmManganese-transport protein of S. pneumoniae into a shape in which it can't accept manganese. It is known that manganese is essential for S. pneumoniae infection to occur, so this research offers a chance to... Read More

YOUR GUT NEEDS BACTERIA TO MAKE MORE SEROTONIN

A new study from CalTech suggests that serotonin levels may be regulated to some degree by the gut microbiome. Researchers are investigating the degree to which bacteria in the guts of mice are able to confer serotonin-dependent function in comparison to control, or "germ-free" mice. Further s... Read More

A “Polio Warrior” Recounts Decades of Struggle Toward Eradication

Science writer Maryn McKenna interviews John Sever, MD, PhD, former chief of infectious diseases at the National Institutes of Health and current vice-chairman of Rotary’s International PolioPlus Committee, about the early days of the polio struggle and the introduction of the polio vaccine.

... Read More

BacterioFiles 210 - Archaea Acquired Alternative Abilities

This episode: Genes taken from bacteria may have been important for the evolution of distinct groups of archaea!


(7.4 MB, 8 minutes)


Show notes: 
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TWiV 332: Vanderbilt virology

Host: Vincent Racaniello


Guests: Seth BordensteinJames Crowe... Read More

A transmissible cancer of soft-shell clams

A leukemia-like cancer is killing soft-shell clams along the east coast of North America. The cancer is transmitted between animals in the ocean, and appears to have originated in a single clam as recently as 40 years ago. Read More

Can Humans Get Norovirus From Their Dogs?

Human norovirus may infect our canine companions, according to research published online April 1 in the Journal of Clinical Microbiology, a publication of the American Society for Microbiology. That raises the possibility of dog-to-human transmission, said first author Sarah Caddy, VetMB, PhD, M... Read More

NIH funds 9 antimicrobial resistance diagnostics projects

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded more than $11 million in first-year funding for nine research projects supporting enhanced diagnostics to rapidly detect antimicrobial-resistant bacteria. The awardee institu... Read More

Anti-HIV antibody shows promise in first human study

A single infusion of an experimental anti-HIV antibody called 3BNC117 resulted in significantly decreased HIV levels that persisted for as long as 28 days in HIV-infected individuals, according to Phase 1 clinical trial findings published online today in Nature. Read More

CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections

CAMBRIDGE, Mass. (April 3, 2015) - By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there... Read More

Pictures Considered #25. Getting A Ride

From Moselio Shaechter of ASM's Small Things Considered:

"A recent review article deals with the fascinating phenomenon of pathogens exiting from their host cell. Sometimes, one pathogen helps another one in transmission to the next host. In one case, a Candida albicans hypha caught in the ac... Read More
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