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TWiV 326: Giving HIV a flat tyr

Hosts: Vincent RacanielloAlan Dove, and  Read More

Unlocking the Key to Immunological Memory in Bacteria

A powerful genome editing tool may soon become even more powerful. Researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) have unlocked the key to how bacteria are able to “steal” genetic information from viruses and other foreign invaders for use in their own immunological me... Read More

WHO calls for action over Mers virus

Too little is being done to control the spread of Middle East Respiratory Syndrome, which has infected 50 people in Saudi Arabia so far this month, the World Health Organization has warned.

The rising number of cases in health-care facilities indicates current infection-control measures are n... Read More

Burden of Clostridium difficile Infection in the United States

The deadly bacterial infection Clostridium difficile is estimated to have afflicted almost half a million Americans and caused 29,000 deaths in 2011, according to a study by the Centers for Disease Control and Prevention published Wednesday in The New England Journal of Medicine. The estimate is... Read More

Liberia’s President Urges U.S. to Continue Ebola Aid

President Ellen Johnson Sirleaf of Liberia on Friday urged the United States to maintain its assistance to her country as it continues to fight to recover from the Ebola outbreak, which began about one year ago.

In a meeting at the White House with President Obama, Ms. Johnson Sirleaf asked f... Read More

An aggressive form of HIV uncovered in Cuba

Engaging in unprotected sex with multiple partners increases the risk of contracting multiple strains of HIV, the virus that causes AIDS. Once inside a host, these strains can recombine into a new variant of the virus. One such recombinant variant observed in patients in Cuba appears to be much ... Read More

Michael Goldberg, Thirty Years The ASM's Executive Director

You must have heard it said that no one is indispensable to an institution. Maybe so, but such truths come in degrees. Every so often someone comes along who makes a genuine difference in how an organization functions. I turn here to Michael Goldberg, who thirty years ago began a most distinguis... Read More

Q&A: Seth Mnookin on vaccination and public health

Seth Mnookin, an assistant professor of science writing and associate director of MIT's Graduate Program in Science Writing, is the author of "The Panic Virus: The True Story Behind the Vaccine-Autism Controversy", an acclaimed book that examines how inaccurate scientific reports linking vaccine... Read More

TWiP 84: Bigfoot

Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study.


Hosts: Vincent Racaniello Read More

TWiP 84 letters

 


Jesse writes:


Doctors TWiP,


I liked the discussion of the interaction of bacteria and Leishmania in sandfly guts; it was very interesting! Here is another suggestion if you need a topic to discuss:


Delivery of a functional anti-trypanoso... Read More

Blocking HIV infection with two soluble receptors

Because viruses must bind to cell surface molecules to initiate replication, the use of soluble receptors to block virus infection has long been an attractive therapeutic option. Soluble receptors have been developed that block infection with rhinoviruses and HIV-1, but these have not been licen... Read More

Ebolavirus will not become a respiratory pathogen

An otherwise balanced review of selected aspects of Ebolavirus transmission falls apart when the authors hypothesize that ‘Ebola viruses have the potential to be respiratory pathogens with primary respiratory spread.’

The idea that Ebolavirus might become transmitted by the respiratory route ... Read More

Bacteria in marine sponges harvest phosphorus for reef community

Significant accumulations of polyphosphate granules have been found in three common sponge species of the Caribbean coral reef, indicating that microorganisms that live on marine sponges are pulling phosphorus out of the water to feed themselves and survive in a deep-water environment where very... Read More

Widely used food additives promotes colitis, obesity and metabolic syndrome, shows study of emulsifiers

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter the gut microbiota composition and localization to induce intestinal inflammation that promotes the development of inflammatory bowel disease and metabolic syndrome, new research shows.

Click ... Read More

A Pill That Mimics the Immune System

The human body doesn’t like outsiders. When a foreign pathogen or substance, say an unwanted virus, finds its way into our blood streams we produce antibodies that the neutralize the threat. These “Y”-shaped proteins are made by a class of white blood cells called plasma cells and bind to molecu... Read More

Mutant Bacteria That Keep on Growing

The typical Escherichia coli, the laboratory rat of microbiology, is a tiny 1-2 thousandths of a millimeter long. Now, by blocking cell division, two researchers at Concordia University in Montreal have grown E. coli that stretch three quarters of a millimeter. That's up to 750 times their norma... Read More

Infections With Dangerous Gut Microbe Still On The Rise

A potentially life-threatening gastrointestinal infection is more common than previously estimated, federal health officials reported Wednesday.

The infection, caused by a bacterium known as Clostridium difficile, or C-diff, causes nearly 500,000 illnesses in the United States each year and k... Read More

Research Shows Asian Herb Holds Promise as Treatment for Ebola Virus Disease

New research that focuses on the mechanism by which Ebola virus infects a cell and the discovery of a promising drug therapy candidate is being published February 27, 2015, in the journal Science. Dr. Robert Davey, scientist and Ewing Halsell Scholar in the Department of Immunology and Virology ... Read More

Malaria transmission linked to mosquitoes’ sexual biology

Sexual biology may be the key to uncovering why Anopheles mosquitoes are unique in their ability to transmit malaria to humans, according to researchers at Harvard T. H. Chan School of Public Health and University of Perugia, Italy. Through analysis of 16 Anopheles genomes, they found that these... Read More

A new understanding of Alzheimer’s

Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which are post-mitotic cells, and plays a critical role in the emergence of A... Read More
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