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MDR Infection Risk Rises With Each Hospital Day

Extended stays in hospital appeared to increase the risk of infection with a multidrug-resistant Gram-negative pathogen, researchers said.

In a single-center study, the risk of such infection rose by 1% for every day in hospital, according to Tonya Smith, PharmD, of the University of Utah.

... Read More

Gene sequencing refines threatening parasite list

Twenty-six species of Cryptosporidium have been recognised and 18 species declared non-valid in a recent shake-up of the parasite's taxonomy using DNA sequencing techniques.

Cryptosporidium is the second biggest cause of infant diarrhoea and death in developing countries, and is found across ... Read More

Vaginal Microbe Yields Novel Antibiotic

Bacteria living on human bodies contain genes that are likely to code for a vast number of drug-like molecules — including a new antibiotic made by bacteria that live in the vagina, researchers report in this week's issue of Cell.

The drug, lactocillin, hints at the untapped medical potential... Read More

Cancer Survivor Saved by Measles Virus Raises Funds for Expanded Trial

After battling blood cancer for 10 years, Stacy Erholtz has no signs of the disease, thanks to an experimental treatment that used an engineered version of the measles virus.

Now, a year after finishing her treatment, the 50-year-old mother of three is transitioning from patient to advocate, ... Read More

One Dose of Flu Drug Shortens Fever

A single dose of an investigational influenza drug was able to reduce the duration of fever and viral shedding, researchers said here.

In a combined analysis of two randomized placebo-controlled trials, the neuraminidase inhibitor peramivir (Rapivab), given by injection within 48 hours of sym... Read More

Self-Assembly For Me

I have the grating feeling that the subject of self-assembly of complex biological structures may not always amass the level of respect it deserves. I reckon that its importance is generally appreciated but, as topics go, it tends at times to be set aside. Yet, this is one of the most magnificen... Read More

Researchers Unlock the Genetic Code of Cancer-Causing Liver Fluke Parasite

An international team of scientists from Singapore, Thailand, China and Australia has cracked the genetic code of the liver fluke parasite, Opisthorchis viverrini, using a unique DNA analysis technique developed at A*STAR’s Genome Institute of Singapore (GIS).

GIS’s DNA analysis technique ha... Read More

Ebola genomes sequenced

Speedy analysis reveals mutations, insights into outbreak, along with clues to origin, spread.

Responding rapidly to the deadly outbreak of Ebola virus disease (EVD) in West Africa, a team of researchers from the Broad Institute and Harvard University, working with the Sierra Leone Ministry o... Read More

How evolutionary principles could help save our world

The age of the Anthropocene--the scientific name given to our current geologic age--is dominated by human impacts on our environment. A warming climate. Increased resistance of pathogens and pests. A swelling population. Coping with these modern global challenges requires application of what one... Read More

DIY Droplet Lens, finalist, 2014 Eureka Prize for Innovative Use of Technology

The traditional light microscope is bulky and expensive. Dr Tri Phan and Dr Steve Lee from the Garvan Institute of Medical Research and Australian National University used gravity to manufacture high-performance polymer lenses. These can be seamlessly integrated with 3D printing and mini-LEDs to... Read More

Watching an Endosymbiont Becoming an Organelle?

Ah, endosymbiosis and the origin of eukaryotic cells… Wasn't this one of the grandest of all the grand events in Biology? In its ability to boggle the mind, it comes in second only to the origin of life. This, one of the most decisive events in evolution, had a unique character. Instead of new t... Read More

How I Learned to Think Like a Mushroom

We need fungal Solutions to Pollution, Global Pandemics, and Starvation, says Tradd Cotter, a microbiologist and professional mycologist.

I have been studying mushrooms, inside and out, macroscopically and microscopically, for the past 22 years. At times I imagine myself deep into their chemi... Read More

Progress in the fight against harmful fungi

A group of researchers at the Max F. Perutz Laboratories has created one of the three world's largest gene libraries for the Candida glabrata yeast, which is harmful to humans. Molecular analysis of the Candida glabrata fungus mutations led to the discovery of 28 new genes that are partly respon... Read More

Scientists Call for Investigation of Mysterious Cloud-like Collections in Cells

About 50 years ago, electron microscopy revealed the presence of tiny blob-like structures that form inside cells, move around and disappear. But scientists still don’t know what they do — even though these shifting cloud-like collections of proteins are believed to be crucial to the life of a c... Read More

New Tracking Technologies Aim to Prevent Sloppy Handling at U.S. Biolabs

Two months after safety breaches at federal labs first set off a public furor, top health officials are auditioning new checks on worker safety including specialized time-lapse cameras and digital worksheets to track crucial steps such as bacterium inactivation. The goal: to prevent future debac... Read More

Scientists develop ‘electronic nose’ for rapid detection of C-diff infection

A fast-sensitive “electronic-nose” for sniffing the highly infectious bacteria C-diff, that causes diarrhoea, temperature and stomach cramps, has been developed by a team at the University of Leicester.

Using a mass spectrometer, the research team has demonstrated that it is possible to ident... Read More

BacterioFiles 183 - Simplex-Sick Stem Cell Salve

This episode: Cancer-killing viruses could work even better when loaded into stem cells!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

A new way to diagnose malaria

Using magnetic fields, technique can detect parasite’s waste products in infected blood cells.

Over the past several decades, malaria diagnosis has changed very little. After taking a blood sample from a patient, a technician smears the blood across a glass slide, stains it with a special dye... Read More

Pitt-Developed Vaccine Proves Effective Against Deadly Middle East Virus

A vaccine developed by an international team of scientists led by the University of Pittsburgh School of Medicine successfully protects mice against a contagious and deadly virus spreading across the Middle East. The vaccine is a promising candidate for immunizing camels, thought to be the sourc... Read More

"Immortal" Cells from Henrietta Lacks Lead to Updated Rules on Genomic Data Sharing

Scientists who work on genomics and are funded by the US National Institutes of Health (NIH) must post their data online so that others can build on the information, the agency has said in an update to its guidelines.

The change, which expands the remit of an earlier data-sharing policy, is ... Read More
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