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What’s the diference between cow TB and human TB?

In 1901, when Robert Koch proposed that the bacilli causing human and bovine tuberculosis were not identical, this view caused much controversy. 113 years later we know that the bovine tuberculosis agent, Mycobacterium bovis, together with other animal strains, forms a separate phylogenetic line... Read More

Synthesis produces new antibiotic

A fortuitous collaboration at Rice University has led to the total synthesis of a recently discovered natural antibiotic.

The laboratory recreation of a fungus-derived antibiotic, viridicatumtoxin B, may someday help bolster the fight against bacteria that evolve resistance to treatments in h... Read More

Experimental Vaccine For Chikungunya Passes First Test

Scientists have taken the first steps to developing a vaccine for chikungunya — an emerging mosquito-borne virus that has infected more than a half million people in the Western Hemisphere this year. About 600 Americans have brought the virus to 43 states.

The study was small. Only 25 people ... Read More

Small Molecule Acts As On-Off Switch for Nature's Antibiotic Factory

Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines.

Their hope now would be to see whether it is possible to manipulate this switch to make nature's anti... Read More

TWiM 86 Letters

 


Suzanne writes (re Aphids):


The best way to get rid of aphids in the garden (the ants in my yard love to herd them onto my okra) is a sharp stream of water from the hose. Aphids wash right off! They don't tend to come back right away, either.


Read More

Ebola Could Eventually Afflict Over 20,000, W.H.O. Says

As the tally of deaths from the worst known outbreak of the Ebola virus continued its seemingly inexorable rise, the World Health Organization said on Thursday that the epidemic was still accelerating and could afflict more than 20,000 people — almost seven times the current number of reported c... Read More

Mutating virus suppresses cow’s immune response

Bovine viral diarrhea virus infections result in one of the most costly diseases among cattle with losses in U.S. herds estimated at $2 billion per year, according to professor Christopher Chase of the South Dakota State University Veterinary and Biomedical Sciences Department.

"It is an immu... Read More

The Curious Case of a Protein and a Pilus

If you’re like me, every morning you reluctantly roll out of bed and automatically reach for your toothbrush. One of the earliest learned practices of personal hygiene, brushing surely serves more than just preventing daybreak halitosis — but have you ever pondered about the plaque you try to di... Read More

Polio: mutated virus breaches vaccine protection

Thanks to effective vaccination, polio is considered nearly eradicated. Each year only a few hundred people are stricken worldwide. However, scientists are reporting alarming findings: a mutated virus that was able to resist the vaccine protection to a considerable extent was found in victims of... Read More

Malaria’s Clinical Symptoms Fade on Repeat Infections Due to Loss of Immune Cells

Children who repeatedly become infected with malaria often experience no clinical symptoms with these subsequent infections, and a team led by UC San Francisco researchers has discovered that this might be due at least in part to a depletion of specific types of immune cells.

Working in Ugand... Read More

ICAAC 2014 - Tests for Rapid Detection of Antibiotic Resistant Bacteria

Rapid detection of antibiotic resistance is vital in assessing the appropriate antibiotic therapy for an infection. Participants will present data on two new inex... Read More

MERS: Low transmissibility, dangerous illness

Research led by the University of Bonn Virologists reveals transmission rate of the MERS virus

The MERS coronavirus has caused disease outbreaks across the Arabian Peninsula and spread to Europe several times. The severe pneumonia virus has claimed the lives of several hundred people since it... Read More

ICAAC 2014 - New Single-Dose Influenza Drug

An analysis of phase 2 and phase 3 clinical trials shows that a single injected dose of the neuraminidase inhibitor (NAI) paramivir is safe and effective at alleviating influenza symptoms including fever and viral shedding when administered within 48 hours of the onset of symptoms. Researcher... Read More

Bacteria Harbor Secret Weapons Against Antibiotics

The ability of pathogenic bacteria to evolve resistance to antibiotic drugs poses a growing threat to human health worldwide. And scientists have now discovered that some of our microscopic enemies may be even craftier than we suspected, using hidden genetic changes to promote rapid evolution un... Read More

Scientists Finally Catch On to Social Media

In 2011, Emmanuel Nnaemeka Nnadi needed help to sequence some drug-resistant fungal pathogens. A PhD student studying microbiology in Nigeria, he did not have the expertise and equipment he needed. So he turned to ResearchGate, a free social-networking site for academics, and fired off a few e-m... Read More

From bite site to brain: How rabies virus hijacks and speeds up transport in nerve cells

Rabies is usually transmitted through the bite of an infected animal into muscle tissue of the new host. From there, the virus travels all the way to the brain where it multiplies and causes the usually fatal disease. A new article sheds light on how the virus hijacks the transport system in ner... Read More

Scientists discover hazardous waste-eating bacteria

Tiny single-cell organisms discovered living underground could help with the problem of nuclear waste disposal, say researchers involved in a study at The University of Manchester.

Although bacteria with waste-eating properties have been discovered in relatively pristine soils before, this is... Read More

ICAAC 2014 - New Targets for SARS/MERS Drugs

Middle East respiratory syndrom... Read More

Farmers Fight Poisonous Wheat Fungus with Cleaning and Waiting

Dave Wiechert of Nashville, Illinois, does good business most years cleaning seed for farmers in preparation for planting season. But this year, Wiechert is doing big business after harvest: cleaning fungus off wheat so farmers can sell it.

The "head scab" fungus can produce vomitoxin, a chem... Read More

Artificial Spleen Cleans Ebola from Blood

Researchers have developed a high-tech method to rid the body of infections — even those caused by unknown pathogens. A device inspired by the spleen can quickly clean blood of everything from Escherichia coli to Ebola, researchers report on September 14 in Nature Medicine.

Blood infections c... Read More
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