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Malaria parasites sense and react to mosquito presence to increase transmission

Many pathogens are transmitted by insect bites. The abundance of vectors (as the transmitting insects are called) depends on seasonal and other environmental fluctuations. A new article demonstrates that Plasmodium parasites react to mosquitoes biting their hosts, and that the parasite responses... Read More

Indian doctors explore disruptive technologies

Healthcare bills continue to account for one the highest out-of-pocket expenses for India’s poor. And yet, quality healthcare remains a distant dream. According to the Healthcare and Equity in India, 2011, report by The Lancet, expenditure on drugs represents 70-80% of out-of-pocket expenditure ... Read More

ICAAC 2014 - New Single-Dose Influenza Drug

An analysis of phase 2 and phase 3 clinical trials shows that a single injected dose of the neuraminidase inhibitor (NAI) paramivir is safe and effective at alleviating influenza symptoms including fever and viral shedding when administered within 48 hours of the onset of symptoms. Researcher... Read More

Genetically Engineered Bacteria Could Repair Ships

Shellfish such as mussels and barnacles secrete very sticky proteins that help them cling to rocks or ship hulls, even underwater. Inspired by these natural adhesives, a team of MIT engineers has designed new materials that could be used to repair ships or help heal wounds and surgical incisions... Read More

Mapping could help stop Ebola's spread

Whether it’s the Black Death of 1350 or the Ebola virus in West Africa, one thing deadly pandemics have in common is that their progress takes a geographical course. But researcher Lars Skog at KTH Royal Institute of Technology is one of those developing geoinformation systems that can help heal... Read More

Fighting Poisons With Bacteria - Going Inside the Rice Microbiome

When Harsh Bais grows rice plants in trays of water in his greenhouse at the University of Delaware, he can easily spot the ones that have been exposed to arsenic: They are stunted, with shorter stems and shrunken, yellow-tinged leaves.

Dr. Bais is working to develop rice plants that take up ... Read More

ICAAC 2014 - New Antifungal Option for Cancer Patients

A newly developed antifungal, isavuconazole, is as effective as an existing drug, voriconazole against invasive mold disease in cancer patients with less adverse ... Read More

Magical Monsoon:rAiNs and Geosmin

A Geosmin Story:
A Musty / Muddy smell - the earthy odour after a heavy spatter of rain is aesthetic to senses.
A poet sitting in such ambiance lets his thoughts to wander randomly and comes out with a sweet piece of write up.
An Artist can do wonders on his canvas flowing with the mood.
Man... Read More

Enterovirus D68 sickens more than a dozen in New York

More than a dozen cases of Enterovirus D68 have been confirmed in New York state, according to officials.

"EV-D68 is causing cases of severe respiratory illness ... sometimes resulting in hospitalization, especially among children with asthma," the NYS Department of Health said in a statement... Read More

White House Unveils Strategy to Combat Antibiotic Resistance

Antibiotic resistance poses a dire threat in hospitals and communities. To help limit such risk, health care professionals should begin sequencing the DNA of offending bacteria, the White House’s council of science advisors said in a new report. Armed with genome-sequencing technology that enabl... Read More

TWiV 303: Borna this way

The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome.


Hosts: Vincent Racaniello Read More

White House Fact Sheet: US Takes Actions to Combat Antibiotic-Resistant Bacteria

Today, President Obama signed an Executive Order directing key Federal departments and agencies to take action to combat the rise of antibiotic-resistant bacteria. The Administration also released its National Strategy on Combating Antibiotic-Resistant Bacteria. In addition, the President’s Cou... Read More

Five Questions about Filoviruses

The virus family Filoviridae is home to Ebola virus, as well as several other viruses that can cause severe hemorrhagic fever in humans and other primates. Ebola virus is in the news because of the outbreak in Guinea that has spread to several neighboring African countries. The fatality rate of ... Read More

'Immortal' flatworms: Weapon against bacteria

A novel mode of defense against bacteria, such as the causal agent of tuberculosis or Staphylococcus aureus, has been identified in humans by studying a small, aquatic flatworm, the planarian. This discovery highlights the importance of studying alternative model organisms, and opens the way tow... Read More

How evolutionary principles could help save our world

The age of the Anthropocene--the scientific name given to our current geologic age--is dominated by human impacts on our environment. A warming climate. Increased resistance of pathogens and pests. A swelling population. Coping with these modern global challenges requires application of what one... Read More

Vaginal Microbe Yields Novel Antibiotic

Bacteria living on human bodies contain genes that are likely to code for a vast number of drug-like molecules — including a new antibiotic made by bacteria that live in the vagina, researchers report in this week's issue of Cell.

The drug, lactocillin, hints at the untapped medical potential... Read More

BacterioFiles 183 - Simplex-Sick Stem Cell Salve

This episode: Cancer-killing viruses could work even better when loaded into stem cells!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

Creative Classroom: The ticks ‘come marching in’ in singing professor’s microbiology class

At the end of a recent “Medical Microbiology” class taught by Dr. Sheldon Campbell, students clapped, cheered heartily, and stomped their feet on the floor. A couple of them even shouted “Encore!”

It’s not quite the reaction one would expect from medical students who just spent 45 minutes lea... Read More

Genomic and Cellular Complexity from Symbiotic Simplicity

The more that biologists study symbiotic microorganisms and their vast influence on animals, the more nature’s networkism unfolds in a continuum at different biological scales. In this issue, Van Leuven et al. illuminate how a stable and longstanding animal-microbe mutualism increased its interg... Read More

Motorcycling to Ebola Treatment Could Spread the Infection

Ambulances are scarce in areas of west Africa roiled by the Ebola outbreak, so when ill patients and their families need to go to the clinic they often turn to the next best thing—a motorcycle taxi. An ill passenger will wrap her arms around the driver’s waist and away they will go—sometimes dri... Read More
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