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MWV Episode 94 - TWiM #99: Careers in Biodefense
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TWiM 97 Letters


Dennis writes:
hi Doc,


A paper just published in nature:


http://www.nature.com/nature/journal/vaop/ncurrent/pdf/nature14098.pdf


reports an effective antibiot... Read More

First results from an Oxford University trial of an Ebola vaccine (video)

A trial of a GSK/NIH candidate Ebola vaccine at Oxford University suggests the vaccine has an acceptable safety profile and is able to generate an immune response.
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Why we haven't eradicated the plague

More than 600 years after the bubonic plague wiped out about half of Europe, scientists still don’t fully understand how bacteria that cause the disease travel from the site of a fleabite to the lymph nodes, where the rampage truly begins.

Researchers who’ve been studying the bacteria say the... Read More

The Forgotten Plague, Chapter 1(video)

By the dawn of the 19th century, tuberculosis had killed one in seven of all people that had ever lived. Doctors believed it was hereditary, but had begun to observe that fresh air and outdoor living could sometimes change the course of the illness. Physician and TB patient Edward Trudeau was co... Read More

TWiV 325: Wildcats go viral

Hosts: Vincent Racaniello


Guests: Rollie Clem and Lorena Passarelli


{audio... Read More

TWiM 98 Letters

 


Patrick writes:


Hi Vincent,


I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More

Breastfeeding, Other Factors Help Shape Immune System Early in Life

Henry Ford Hospital researchers say that breastfeeding and other factors influence a baby’s immune system development and susceptibility to allergies and asthma by what’s in their gut.

The striking findings from a series of studies further advance the so-called hygiene hypothesis theory that ... Read More

Researchers discover critical molecule in fight against lung infection

A Montana State University graduate student who wants to reduce the number of people dying from lung infections has discovered a molecule that's critical for immunity.

Caffrey researches the early immune response against Aspergillus fumigatus, a common mold that can be found in soil or compos... Read More

A Beautiful Wallpaper Made With Smallpox Vaccine

We’re in the midst of an outbreak of debate, people arguing the merits of vaccinations. Its symptoms include feverish rhetoric and noxious op-eds. In an attempt to stem the spread of unhealthy attitudes toward science and misinformation about vaccines, the Bill & Melinda Gates Foundation sponsor... Read More

World Health Organization approves 15-minute Ebola detection test

Until now, the standard way to check for Ebola in the region was to use the nucleic acid test, which works by identifying the genetic materials of the virus from a blood sample. Yet the test requires a full lab to succeed, and it takes between 12 to 24 hours to process the results. In comparison... Read More

Live bacterium depicted using X-ray laser

An international team led by Uppsala University scientists has succeeded, for the first time, in depicting intact live bacteria with an X-ray laser. This technique, now described in the journal Nature Communications, can give researchers a clearer understanding of the complex world of cells.

... Read More

Fecal transplants may up risk of obesity onset

Fecal microbiota transplantation can be effective for recurrent Clostridium difficile infection, but new-onset obesity could follow transplant of stool from an overweight donor, a new study finds

"Fecal transplant has helped a lot of people who have run out of other options," Dr. Colleen R. K... Read More

Drug targeting ebola virus protein VP24 shows promise in monkeys

An experimental medication that targets a protein in Ebola virus called VP24 protected 75% of a group of monkeys that were studied from Ebola virus infection, according to new research conducted by the U.S. Army, in collaboration with Sarepta Therapeutics, Inc. The study was published this week ... Read More

Superbug outbreak has killed two at UCLA medical center

This week, doctors at the University of California Los Angeles Medical Center discovered that a contaminated medical tool had been spreading antibiotic-resistant bacteria to patients. The bacteria, known as carbapenem-resistant Enterobacteriaceae or CRE, has been called a “nightmare” bacteria by... Read More

When strep throat is something else: Forgotten bacterium is the cause of many severe sore throats in young adults

New research from the University of Alabama at Birmingham suggests that Fusobacterium necrophorum more often causes severe sore throats in young adults than streptococcus — the cause of the much better known strep throat. The findings, published today in the Annals of Internal Medicine, suggest ... Read More

Lyme disease costs up to $1.3 billion per year to treat, study finds

Lyme disease, transmitted by a bite from a tick infected by the Borrelia burgdorferi bacteria, had long been considered easy to treat, usually requiring a single doctor's visit and a few weeks of antibiotics for most people.

But new research from the Johns Hopkins Bloomberg School of Public H... Read More

Common gum-disease bug may also give cancer a boost

What do your mouth and your behind have in common? They're linked by a bug that we thought was usually benign, but may in fact have a much darker side.

Fusobacterium nucleatum is a common bacterium that lives in our mouths, often without causing any ill effects, although it is also frequently... Read More

PhatoMap of New York Subway System

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs — and even DNA fragments associated with anthrax and Bubonic plague — according to a citywide microbiome map published today by Weill Corne... Read More

Coral reef symbiosis: Paying rent with sugar and fat

Scientists have revealed how coral-dwelling microalgae harvest nutrients from the surrounding seawater and shuttle them out to their coral hosts, sustaining a fragile ecosystem that is under threat.

Coral reefs are the jungles of the oceans, home to some of the planet's most fertile fishing g... Read More

Airport screening misses half of disease cases but could be improved

Scientists have shown that airport screening for disease will often miss half or more of infected travelers, but can be improved by customizing to pathogens. The findings are published in the journal eLife.

They present options for policy makers; for example whether resources would be better ... Read More
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