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Anglo Saxon remedy kills hospital superbug MRSA

A strange concoction of foods and wine seem to rival the efficacy of currently used antimicrobials in hard-to-treat skin infections, such as MRSA. When combined properly, cow bile salts, wine, garlic, leeks, and copper were as effective as Vancomycin in eliminating all soil bacteria introduced ... Read More

To fight nasty digestive bugs, scientists set out to build a better gut -- using stem cells

Researchers at the University of Michigan are studying the ecology of microbes in the GI tract in hopes of developing novel diagnostic tests and effective treatments for intestinal disease. How are they studying this? By creating tiny gut ecosystems! Using undifferentiated stem cells, the inv... Read More

STOP SUPERBUGS BY TURNING UP THE HEAT

U. MINNESOTA (US) — One effective way to fight the spread of antibiotic-resistant bacteria, known as “superbugs,” may be to treat municipal wastewater solids at higher temperatures. Heating the solid waste to 130 degrees Fahrenheit (55 degrees Celsius) was particularly effective in eliminating ... Read More

Microbes scared to death by virus presence

A recent study published in mBio suggests that certain archaea go dormant in the presence of bacteriophage viruses, ceasing to reproduce or carry on cellular processes essential to their survival. The study, which was conducted at the University of Illinois, sheds light on the co-evolution of a... Read More

Can Humans Get Norovirus From Their Dogs?

Human norovirus may infect our canine companions, according to research published online April 1 in the Journal of Clinical Microbiology, a publication of the American Society for Microbiology. That raises the possibility of dog-to-human transmission, said first author Sarah Caddy, VetMB, PhD, M... Read More

TWiM 101 Letters

Eric writes:


Dear TWIMers,


I am a retired computer programmer and also a free market libertarian. I listened to a recent podcast where the subject of mandatory hand washing by food workers was tossed around. I would like to present a few more of the free marke... Read More

HOW MAPLE SYRUP COULD IMPROVE ANTIBIOTICS

A concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics, according to laboratory experiments.

The findings, which will appear in the journal Applied and Environmental Microbiology, suggest that combining maple syrup extract with common antibiotics ... Read More

Comparing the genomes of the leprosy bacteria

Leprosy is a chronic infection of the skin, peripheral nerves, eyes and mucosa of the upper respiratory tract, affecting over a quarter million people worldwide. Its symptoms can be gruesome and devastating, as the bacteria reduce sensitivity in the body, resulting in skin lesions, nerve damage ... Read More

Chlorine use in sewage treatment could promote antibiotic resistance

Chlorine, a disinfectant commonly used in most wastewater treatment plants, may be failing to completely eliminate pharmaceuticals from wastes. As a result, trace levels of these substances get discharged from the plants to the nation's waterways. And now, scientists are reporting preliminary st... Read More

TWiV 332: Vanderbilt virology

Host: Vincent Racaniello


Guests: Seth BordensteinJames Crowe... Read More

microbe subway map

Explore an awesome map of microbes on the NY subways for yourself! Read More

CRISPR-Cas editing of C. albicans holds promise for overcoming deadly fungal infections

CAMBRIDGE, Mass. (April 3, 2015) - By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans' genome systematically--an approach that could help identify novel targets for therapies against this serious pathogen for which there... Read More

TWiV 330: A swinging gate

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

New mechanisms of 'social networking' in bacteria

AMHERST, Mass. - Bacteria have traditionally been viewed as solitary organisms that "hang out on their own," says molecular biologist Kevin Griffith of the University of Massachusetts Amherst. However, scientists now realize that in fact, bacteria exhibit social behavior within groups. Read More

How a deadly fungus evades the immune system

The fungus Candida albicans, which can be fatal in up to 40% of patients with a systemic infection, is being reconsidered by a team of researchers from the University of Toronto. They investigated alternative explanations to the previously accepted thought that the fungus undergoes a change in ... Read More

Cold Spring Harbor Lab, Seeking Human Subjects, Teams Up With Hospital System

Some of the world’s finest scientists live in a former whaling village on the North Shore of Long Island, in a compound reminiscent of an army post.

In this pastoral setting, they have very self-consciously taken themselves out of the real world into a cerebral one, where they are searching f... Read More

Scientists reveal unique mechanism of natural product with powerful antimicrobial action

A research team at the Scripps Research Institute in Florida has published a study which details the wide-range of function of the natural product borrelidin. Borrelidin is a powerful tRNA-synthetase inhibitor which has been shown to exhibit antimicrobial characteristics, including anti-bacteri... Read More

Purging a virus from organ transplants

Human cytomegalovirus (HCMV) is an extremely common virus, which as other members of the herpes virus family causes life-long infections in humans. Most individuals are exposed to HCMV during childhood, yet symptoms can be easily fought off by a healthy immune system. However, infections can be ... Read More

CRISPR-Cas genome editing of Candida albicans holds promise for overcoming deadly fungal infections

By modifying the CRISPR-Cas genome editing system, Whitehead Institute researchers are now able to manipulate Candida albicans’ genome systematically—an approach that could help identify novel targets for therapies against this serious pathogen for which there are a limited number of anti-fungal... Read More

Three Roads to Cellular Compartments

In a recent post to ASM's blog Small Things Considered, Merry Youle writes a wonderful, sometimes thrilling description of the different forms of cellular compartments that have evolved over the last 4 billion years or so. From compartmentalized, lipid-bound membranes in eukaryotes to microcomp... Read More
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