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TWiV 336: Brought to you by the letters H, N, P, and Eye

 Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler


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The TWiVsters explore mutations in the interferon pathway associated with severe influenza in a child... Read More

Designer viruses for killing tumor cells

A major goal of viral oncotherapy – the use of viruses to destroy tumors – is to design viruses that kill tumor cells but not normal cells. Two adenoviruses provide perfect examples of how this specificity can be achieved.

Adenovirus CG0070, designed to treat bladder cancer, and adenovirus O... Read More

Malaria parasite's essential doorway into red blood cells illuminated

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite. The presence of this protein, called CD55, was found to be critical to... Read More

Liberia conducts first polio, measles immunizations since Ebola outbreak.

Monrovia, 8 May 2015 – A week-long campaign to vaccinate more than 600,000 children against polio and measles kicks off today in Liberia, led by the Ministry of Health and Social Welfare, and supported by the Centers for Disease Control (CDC), the United Nations Children’s Fund (UNICEF) and the ... Read More

TWiM #103: The battle for iron

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

TWiM 103 Letters

Bailey writes:


Hey Vincent, Elio, Michele and Michael!


I'm a first year microbiology graduate student at UC Berkeley and an avid listener of twim. Elio's snippet from the most recent podcast reminded me of a personal anecdote that might be useful to share with... Read More

Smartphone adapted for use as a video microscope to detect parasites in blood in under resourced communities

This is a good news story all around. UC Berkeley engineers, Michael D'Amrosio and Matthew Bakalar (UC Berkeley Bioengineering) with medical personal from NIAID, Dr. Thomas Nutaman and his collaborators from Cameroon and France collectively took the omni-present global resource, a standard smar... Read More

DISEASES LOOM LARGE FOR TROPICAL CORALS

As greater atmospheric carbon dioxide boosts sea temperatures, tropical corals face a bleak future. New climate model projections show that conditions are likely to increase the frequency and severity of coral disease outbreaks. Read More

Ebola experience is a wake-up call for the WHO

"The WHO, largely unchanged since its creation, is ill-equipped to deal with the disease threats that this new world creates...the recent Ebola outbreak is a case in point. Even the WHO's director-general, Margaret Chan, said her organisation was "overwhelmed" and admitted that a crisis on that ... Read More

Ocean currents disturb methane-eating bacteria

Bacteria that feed on methane can control its concentration once it is released from the ocean floor. This can potentially stop the greenhouse gas from entering the atmosphere. But ocean currents can easily disturb dinner, according to new study in Nature Geoscience.

There is a large, and rel... Read More

Loyola shows oral spores of harmless C. difficile prevents repeat infection

In what is a major step towards the prevention of recurring bouts of Clostridium difficile (Cdiff) infection, an international team led by Dale Gerding, MD, Hines Veterans Administration (VA) research physician and professor of Medicine at Loyola University Chicago Stritch School of Medicine, ha... Read More

Hepatitis C common among HIV-positive patients in sub-Saharan Africa

A new study has found high levels of infection with hepatitis C (HCV) across Africa, particularly in people infected with HIV. Read More

A Flu Epidemic That Threatens Birds, Not Humans

Although much of the country has barely noticed, avian influenza — a version of the virus that generated “Killer Bird Flu!” headlines a decade ago — is now sweeping the Midwest. Read More

Study reveals how a Rab protein controls HIV-1 replication

HIV-1 replication requires the coordinated movement of the virus's components toward the plasma membrane of an immune cell, where the virions are assembled and ultimately released. A study in The Journal of Cell Biology reveals how a Rab protein that controls intracellular trafficking supports H... Read More

Bacterial viruses: Tools of the trade

Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich demonstrate for the first time that bacteriophages (bacterial viruses) carry genetic instructions for proteins that mediate the transport of their DNA to specialized replication sites in the host cell. Read More

Study finds swine farming is a risk factor for drug-resistant staph infections

Swine farmers are more likely to carry multidrug-resistant Staphylococcus aureus (S. aureus or "staph") than people without current swine exposure, according to a study conducted by a team of researchers from the University of Iowa, Kent State University, and the National Cancer Institute. Read More

TWiV 335: Ebola lite

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiP 88: French foreign lesion

Vincent, Dickson, and Daniel discuss how a secreted protein from the protozoan parasite Theileria transforms its host cells via a cellular proto-oncogene.


Hosts:  Read More

TWiP 88 letters

 


Robin writes:


Cutaneous leishmaniasis.
CL has been endemic in Italy at a relatively constant level since the 1970s, in the same areas that are endemic for VL. CL is largely underreported to the MoH. Only cases that are diagnosed and treated in hosp... Read More

A new cell receptor for rhinovirus

Rhinovirus is the most frequent cause of the common cold, and the virus itself is quite common: there are over 160 types, classified into 3 species. The cell receptor has just been identified for the rhinovirus C species, which can cause more severe illness than members of the A or B species: it... Read More
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