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Getting Started with MicrobeWorld

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TWiP 83: Hidden costs of infection

Vincent, Dickson, and Daniel present a new case study, and discuss the effect of chronic malaria infection on wild warbler life span and telomere degradation.


Hosts: Vincent Racaniello Read More

BacterioFiles 248 - Tiny Travelers Transport Toxin Trashers

This episode: Bacteria that swarm around in groups carry other bacteria with them that can be helpful for degrading toxins!


(14.2 MB, 15.5 minutes)


Show notes: 
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BacterioFiles 258 - Transformed Toxin Translocates Treatments

This episode: Bacterial toxins could be modified to deliver life-saving proteins into neurons!


(11.1 MB, 12.1 minutes)


Show notes: 
Journal Paper:

Chen C, Przedpelski A, Tepp WH, Pellett S, Johnson EA, Barbieri JT. 2015.... Read More

BacterioFiles 197 - Fucose Feeds Friendly Fighters

This episode: When sensing an infection, mice make sure to keep their gut bacteria well-fed. And it pays off!


(11.8 MB, 13 minutes)


Show notes: 
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TWiP 106: Trematode stormtroopers in snail wars

The TWiP triumvirate solves the case of the Missionary in Kenya, and review the finding of a soldier caste in flatworms that parasitize snails.


Hosts: Vincent Racaniello Read More

BacterioFiles 222 - Cells Store Solar Sparks

This episode: Bacteria engineered to produce liquid fuel can eat carbon dioxide and hydrogen from solar-powered water-splitting!


(11.2 MB, 12.25 minutes)


Show notes: 
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BacterioFiles 253 - Probiotics Promote Protective Pathway

This episode: In mice and fruit flies, Lactobacillus species induce gut cells to protect themselves from reactive oxygen compounds!


(8.2 MB, 8.9 minutes)


Show notes: 
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BacterioFiles 226 - Deep Dwellers Diversify

This episode: Archaea living in the deep ocean (and their viruses) have clever ways to maintain diversity and adaptability!


(10.3 MB, 11.25 minutes)


Show notes: 
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BacterioFiles 240 - Water Worms Make (carbon) Monoxide Meals

This episode: Marine worms and their microbial symbionts can live on the toxic gas carbon monoxide!


Reminder: this is the last episode for at least a few weeks while I am wrapping up my PhD. See you again when I'm done!

(11.1 MB, 12.1 minutes)


Read More

BacterioFiles 236 - Film Formation Favors Fossilization

This episode: Gut microbes' activity in decaying brine shrimp help promote fossilization of their soft parts!


(8.1 MB, 8.8 minutes)


Show notes: 
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TWiM #130: Interkingdom interactions at ASM Microbe

The TWiMers get together at ASM Microbe 2016 in Boston to speak with David and Vanessa to talk about their work on regulation of bacterial virulence in the gut by bacterial adrenergic sensors, and the physiological mechanisms that make us ill and that help us recover.


Hosts: Read More

MWV Episode 93 - TWiM #95 - A microbe lover in San Diego

Hosts: Vincent Racaniello.


Special guest: Stanley Maloy


Vincent meets up with Stan Maloy o... Read More

TWiM #119: Power of one

Hosts: Vincent RacanielloMichael Schmidt, and Read More

BacterioFiles 225 - Implanting Internal Invader Immunity

This episode: Don't have immunity? Create your own! Scientists engineer cells to destroy their HIV infections using the bacterial immune system!


(14.5 MB, 15.8 minutes)


Show notes: 
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BacterioFiles 256 - Virus Versus Virus

This episode: Viruses can cause host cells to inhibit other viruses!


(8 MB, 8.75 minutes)


Show notes: 
Journal Paper:

Chiba S, Suzuki N. 2015. Highly act... Read More

BacterioFiles 187 - Bacteria Bolster Bedbug Biotin

This episode: Some Wolbachia bacteria produce vitamin B7 for their insect hosts!


(7.1 MB, 7.75 minutes)


Show notes: 
Journal Paper


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TWiP 93 letters

Sandra writes:


Daniel: I was fascinated by your answer to the case from TWIP 91 - the life cycle of the southeast Asian worm (I won't even try to spell it.) Re early symptom coughing & wheezing: if the ED did a chest X-ray out of concern about the lungs, would the... Read More

Microbes After Hours: The Necrobiome - Microbial Life After Death

What happens to us after we die?  A decomposing corpse becomes its own mini-ecosystem, hosting insects, scavengers and multitudes of microbes.  Microbes from the environment, the corpse, as well as the insects and scavengers are blended together and work to recycle tissues back to t... Read More

BacterioFiles 254 - Clostridium Consolidates Combustibles Conversion

This episode: Engineering bacteria to convert cellulose directly into useful biofuels and chemicals can be tricky!


(13.9 MB, 15.2 minutes)


Show notes: 
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TWiM #94: Nitrochondria

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

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