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Rare byproduct of marine bacteria kills cancer cells by snipping their DNA

Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.

The molecule, lomaiviticin A, was previously shown to be lethal to cultured human cancer cells, but the mech... Read More

BacterioFiles 175 - Bacteria Build Better Biofilms

This episode: Engineered bacteria can be made to produce many different useful kinds of biofilm!


(10.5 MB, 11.5 minutes)


Show notes: 
News item 1/ Read More

Natural History is Dying, and We Are All the Losers

A few weeks ago, I came across a new paper in BioScience called “Natural History’s Place in Science and Society” that contained the following graph.

On the right axis and indicated by the line surrounded by dots is the proportion of introductory biology texts devoted to natural history since ... Read More

A Snippet: One Fungus, Two Bacteria

How often have you heard of two or more bacterial species coexisting within the same cell of a host? It’s known to happen with some frequency in some amebas, insects and other invertebrates (including the strange case of the mealybug bacteria, which have an endosymbiotic bacterium that carries a... Read More

ASM GM 2014 - The Effect of Pancreatic Cancer on the Oral Microbiome

In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More

Drugs fail to reawaken dormant HIV infection

Scientists report that compounds they hoped would "wake up" dormant reservoirs of HIV inside immune system T cells -- a strategy designed to reverse latency and make the cells vulnerable to destruction -- have failed to do so in laboratory tests of such white blood cells taken directly from pati... Read More

Bacteria: A day in the life

MIT study finds ocean bacteria follow predictable patterns of daily activity.

We are all creatures of habit, and a new MIT study finds ocean bacteria are no exception.

In a paper published this week in Science, researchers from MIT and elsewhere report that microbes in the open ocean follo... Read More

US Travelers Return Home With Tropical Disease. Will It Spread In The States?

If you happened to be reading state health departments’ outbreak announcements this past weekend, you might have seen something interesting.

(You don’t do this? Hmm.)

Three states — Rhode Island, North Carolina and Tennessee — all said that they have identified residents who have been diag... Read More

More than glitter: Scientists explain how gold nanoparticles easily penetrate cells, making them useful for delivering drugs

A special class of tiny gold particles can easily slip through cell membranes, making them good candidates to deliver drugs directly to target cells.

A new study from MIT materials scientists reveals that these nanoparticles enter cells by taking advantage of a route normally used in vesicle-... Read More

Genomes provide clues for treating leukemia, endometrial cancers

Genomes provide clues for treating leukemia, endometrial cancers

Read More

Biological Samples

ILSbio is the company of choice for research institutions, biotech organizations and pharma companies looking for high quality, documented biological samples to support their research. With a wide range of specimens types available including diseased tissue, FFPE, blood, and serum, collections c... Read More

Killer Silk: Making Silk Fibers That Kill Anthrax and Other Microbes in Minutes

A simple, inexpensive dip-and-dry treatment can convert ordinary silk into a fabric that kills disease-causing bacteria -- even the armor-coated spores of microbes like anthrax -- in minutes, scientists are reporting in the journal ACS Applied Materials & Interfaces. They describe a range of pot... Read More

Why a bacterium got its curve — and why biologists should know

Drawing from his engineering background, Princeton University researcher Alexandre Persat had a notion as to why the bacteria Caulobacter crescentus are curved — a hunch that now could lead to a new way of studying the evolution of bacteria, according to research published in the journal Nature ... Read More

Study examines therapeutic bacteria’s ability to prevent obesity

A probiotic that prevents obesity could be on the horizon.

Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.

“Of course it’s hard to spec... Read More

UEA researchers discover Achilles’ heel in antibiotic-resistant bacteria

Scientists at the University of East Anglia have made a breakthrough in the race to solve antibiotic resistance.

New research published today in the journal Nature reveals an Achilles’ heel in the defensive barrier which surrounds drug-resistant bacterial cells.

The findings pave the way f... Read More

Deadly Human Pathogen Cryptococcus Fully Sequenced

DURHAM, NC - Within each strand of DNA lies the blueprint for building an organism, along with the keys to its evolution and survival. These genetic instructions can give valuable insight into why pathogens like Cryptococcus neoformans -- a fungus responsible for a million cases of pneumonia and... Read More

Bird flu 'danger zones' mapped

The "danger zones" in Asia which are vulnerable to a deadly bird flu have been mapped by scientists.

The virus, called H7N9, has infected 433 people mostly in China and has killed 62.

The study, published in Nature Communications, showed parts of Bangladesh, India and Vietnam could easily ... Read More

HIV, malaria, and tuberculosis: Success of the Millennium shown in most comprehensive study to date

Accelerated progress against the global burden of HIV, malaria, and tuberculosis (TB) has been made since 2000 when governments worldwide adopted Millennium Development Goal 6 to combat HIV/AIDS, malaria, and TB. New estimates from a major new analysis show that worldwide, the number of people l... Read More

A Bird Flu Death in China. What it Means — and Doesn’t Mean

Science and news cycles sometimes converge in unhandy ways. That was the case on on January 1, when word came out of Shenzen, a Chinese city bordering Hong Kong, that a 39-year-old bus driver, surnamed Chen, had died of the H5N1 (or bird flu) virus. The deeply personal tragedy for Chen and his f... Read More

Ancient genetic material from caries bacterium obtained for the first time

A UAB research concludes that the Streptococcus mutans, one of the principal bacteria causing dental caries, has increased the changes in its genetic material over time, possibly coinciding with dietary changes linked to the expansion of humanity.

Click "source" to read more. Read More

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