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BDP FL maleimide - BODIPY analog - fluorescent labeling of proteins

BDP FL maleimide
http://www.lumiprobe.com/p/bodipy-fl-maleimide

BDP FL maleimide is a bright and photostable thiol-reactive dye for protein labeling, an ideal replacement for fluorescein for microscopy. BDP FL is a borondipyrromethene dye which has absorption and fluorescence spectra similar... Read More

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have now discovered how intestinal cells build this specialized structure, which is critical for absorbing nutrients and defending against pathogens. The findings, published April 10 in the journal Cell, reveal a role for adhesion molecules in brush border assem... Read More

Insight into pathogenic fungus

The fungal pathogen Candida albicans causes yeast infections, diaper rashes and oral thrush, and is the most common fungal pathogen to infect humans. Researchers have identified a protein that the fungus uses to defend itself against the human body. Another concern with the fungus is that it can... Read More

Dairy scientist targets heat-resistant microbes

Corralling desperados with names like bacillus and paenibacillus will require ingenuity and an arsenal of weapons. These outlaws aren't rustling cattle—they're making milk sour and cheese soft and crumbly.

For more than a century, milk has been heated to kill any bacteria or pathogens that ca... Read More

Research shows bacteria can combat dangerous gas leaks

Bacteria could mop up naturally-occurring and man-made leaks of natural gases before they are released into the atmosphere and cause global warming - according to new research from the University of East Anglia.

Findings published today in the journal Nature shows how a single bacterial strai... Read More

Superbugs should scare you more than Ebola in US

The first case of Ebola in the United States was announced today, with a patient in Dallas who traveled to the US from Liberia. The resultant hysteria and xenophobia prompts this reminder. There is NO need to panic.

Ebola is NOT transmitted before a patient develops symptoms. Ebola is transmi... Read More

Microgravity research helping to understand the fungi within

(Phys.org) —You may not recognize it by name, but if you have ever had a child with a diaper rash, that child was likely a host to Candida albicans (C. albicans). This unwelcome "guest" can be hard to control, as it can potentially lead to serious illness in humans with weakened immune systems. ... Read More

Brewing yeasts reveal secrets of chromosomal warfare and dysfunction

Using two yeasts that have been used to brew tea and beer for centuries, researchers at Fred Hutchinson Cancer Research Center have revealed how reproductive barriers might rapidly arise to create species boundaries. Schizosaccharomyces pombe has been used to brew beer in Africa, whereas its clo... Read More

Adhering To The 'Replicon Model' The Sloppy Way

Sixty years ago Jacob, Brenner and Cuzin devised their 'Replicon Model', inspiring and useful guideline for replication research ever since. According to the model, a 'Replicon' is a genetic element replicated from a single 'Replicator'—replication origin, in modern terms—and replication is trig... Read More

Amphibian communities collapse in wake of viral outbreak

Two closely related viruses that have been introduced to northern Spain in recent years have already led to the collapse of three different species of amphibian -- the common midwife toad, the common toad, and the alpine newt -- in the protected area of Picos de Europa National Park. In all, six... Read More

The bug that lost a few genes to become Black Death

About 6,000 years ago, a bacterium underwent a few genetic changes. These allowed it to expand its habitat from the guts of mice to that of fleas. Such changes happen all the time, but in this particular instance the transformation eventually resulted in the Black Death that wiped out a third of... Read More

‘Wormy’ Pills Might Fend Off Autoimmune Diseases

Scientists have identified peptides from parasitic hookworms that can calm the body’s immune response and perhaps pave the way to treat autoimmune diseases.

Experts believe the peptide molecules could help explain why worm infections can effectively treat diseases such as multiple sclerosis, ... Read More

Light-Induced Delivery of Nitric Oxide Eradicates Drug-Resistant Bacteria

Researchers at UC Santa Cruz have developed a novel approach for eradicating drug-resistant bacteria from wounds and skin infections, using light to trigger the controlled release of nitric oxide. The UCSC team developed a photoactive compound that releases nitric oxide when exposed to light, an... Read More

From the archives: life at 90°C

Prokaryotes are by far the most successful superkingdom in terms of both biochemical diversity and the variety of environments conquered. Bacteria can be found living in all kinds of adverse conditions; from high alkaline lakes, to below freezing temperature, to hot volcanic vents which in some ... Read More

Six to Tango

One genome at a time can be exciting, but two even more so. I’m not entirely sure why this is, although it may explain our fascination with sex. And what if more than two entities were involved? What if the intimacy were not just between two individual organisms, but between a greater number of ... Read More

Tick protein does the trick to fight infection

A protein in ticks that protects them against the cold could inspire a new class of antibiotics for humans, according to a Yale University study.

Scientists discovered that IAFGP, an antifreeze protein in ticks that kicks in during winter, also fights infection. Synthesizing such a protein ma... Read More

Facilitation of horizontal transfer of antimicrobial resistance by transformation of antibiotic-induced cell-wall-deficient bacteria

It is universally accepted that the use of antibiotics will lead to antimicrobial resistance. Traditionally, the explanation to this phenomenon was random mutation and horizontal gene transfer and amplification by selective pressure. Subsequently, a second mechanism of antibiotic-induced antimic... Read More

The virus detective who discovered Ebola in 1976

Nearly 40 years ago, a young Belgian scientist travelled to a remote part of the Congolese rainforest - his task was to help find out why so many people were dying from an unknown and terrifying disease.

In September 1976, a package containing a shiny, blue thermos flask arrived at the Instit... Read More

A Snippet: One Fungus, Two Bacteria

How often have you heard of two or more bacterial species coexisting within the same cell of a host? It’s known to happen with some frequency in some amebas, insects and other invertebrates (including the strange case of the mealybug bacteria, which have an endosymbiotic bacterium that carries a... Read More

A Cheap, Promising Way to Filter Water: Through A Twig

One way to avoid getting sick while traveling is to only eat fruit that you peel yourself, since plants can filter out bacteria and prevent it from traveling throughout their tissues. Well, why not apply this principle to filtering water directly? A team of scientists have done just that, testi... Read More

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