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MWV Episode 94 - TWiM #99: Careers in Biodefense
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New approach of resistant tuberculosis

Scientists of the Antwerp Institute of Tropical Medicine have breathed new life into a forgotten technique and so succeeded in detecting resistant tuberculosis in circumstances where so far this was hardly feasible. Tuberculosis bacilli that have become resistant against our major antibiotics ar... Read More

Natural Intestinal Flora Strengthens Immune System

Signals from natural intestinal bacteria are necessary for an effective immune response to various viral or bacterial germs. This was the result of experiments by a research team led by Prof. Dr. Andreas Diefenbach and Stephanie Ganal at the Institute of Medical Microbiology and Hygiene of the F... Read More

Protein proves to be vital in immune response to bacteria

A team of researchers led by scientists at Rockefeller University have discovered that a protein once thought to be mainly involved in antiviral immunity is in fact more important in fighting bacterial infections and could provide new mechanisms for treating diseases like tuberculosis, which is ... Read More

Scientists reveal how natural systems limit the spread of "cheating" bacteria

In the first field study of its kind researchers at Royal Holloway, University of London and the University of Oxford have investigated the competitive dynamics of pathogenic and non-pathogenic strains of bacteria.

Bacteria are increasingly seen as living and interacting in groups and sharing... Read More

J&J seeks OK for first drug against resistant TB

Johnson & Johnson said Monday that it is seeking U.S. approval for the first new type of medicine to fight deadly tuberculosis in more than four decades.

The experimental drug, called bedaquiline, also would be the first medicine specifically for treating multi-drug-resistant tuberculosis. Th... Read More

Innate immune system protein provides a new target in war against bacterial infections

Research led by St. Jude Children’s Research Hospital scientists has identified a possible new approach to defeating bacterial infections by targeting an innate immune system component in a bid to invigorate the immune response.

In this study, researchers demonstrated that the primary functio... Read More

Parasite of the Day: Xenopsylla ramesis

There is no parasite that is universally infective, even generalist parasites that can infect many different host species are usually limited to a particular taxonomic group - such as fish, insects, or mammals. Some parasites may infect a broad spectrum of hosts during one stage of their life-cy... Read More

Inspired by nature: Paints and coatings containing bactericidal agent nanoparticles combat marine fouling

Scientists at Johannes Gutenberg University Mainz (JGU) in Germany have discovered that tiny vanadium pentoxide nanoparticles can inhibit the growth of barnacles, bacteria, and algae on surfaces in contact with water, such as ship hulls, sea buoys, or offshore platforms. Their experiments showed... Read More

Time in space may stretch worm lifespan

Scientists studying loss of bone and muscle mass among astronauts find that spaceflight’s effects on microscopic worms may help them live longer.

The researchers discovered that spaceflight suppresses accumulation of toxic proteins that normally accumulate within aging muscle.

In addition,... Read More

The Dog Bacteria That Can Protect You From Asthma

Studies suggest that infants who grow up with dogs in their home are less likely to develop asthma. Researchers may now have found one reason why. Pets, dogs in particular, may protect infants from the effects of a common virus, respiratory syncytial virus (RSV).

Infants with severe RSV infec... Read More

BESC researchers tap into genetic reservoir of heat-loving bacteria

The identification of key proteins in a group of heat-loving bacteria by researchers at the Department of Energy's BioEnergy Science Center could help light a fire under next-generation biofuel production.

Scientists have long been on the hunt for cost-effective ways to break down complex pla... Read More

Oddly Microbial: 86 Million Year-Old Deep Seabed Mystery Cells

Life in a high-pressured environment with practically nothing to eat might be ok for high-fashion models, but it’s an unlikely lifestyle choice for a single cell whose usual overriding goal is to become two cells. Yet the largest living ecosystem on Earth—the deep biosphere—is comprised of micro... Read More

Bacteria a potential threat to nuclear waste repositories

By interacting with the radioactive waste and the materials used to contain it, underground microorganisms may affect the safety of nuclear waste repositories, for better or for worse.

Underground, time appears to stand still. That is one of the reasons why deep geological formations are cons... Read More

Thoughts on the Inaugural Conference on the Microbiology of the Built Environment

". . . a guest post [to microbe.net] by David Thaler, who is one of the Sloan-funded investigators working on the microbiology of the built environment . . ."

"A few thoughts after the Inaugural meeting of Microbiology of the Built Environment Boulder.

My own opinions on these points are s... Read More

TWiV 194: Five postdocs in North America

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Hosts: Vincent Racaniello, Matthew Daugherty, Jondavid d... Read More

Fungi that steal genes from bacteria

In order to survive in complex and interesting environments in the wild, bacteria have a whole arsenal of chemical products that they make within the cell. These chemicals are used for signalling, defence and communication between bacterial cells. One particular group of these chemicals is calle... Read More

Virus Find Helps Mystery Disease Probe in Cambodia

The investigation of a mystery disease that has killed dozens of children in Cambodia is advancing after the discovery in patient samples of a virus that causes hand, foot and mouth disease.

The Institut Pasteur du Cambodge found enterovirus 71 in 15 of 24 patients sampled since mid-June, Phi... Read More

Engineering Life to Survive on Mars and Aid Human Colonization

With NASA’s Curiosity Rover safely on Mars and ready to search for signs of life, back on Earth attempts are underway to engineer bacteria that could thrive on the Red Planet.

A team of undergraduates from Stanford and Brown Universities are busy applying synthetic biology to space exploratio... Read More

Bacterial gene 'therapy' to combat cholera

Cholera is an extremely virulent intestinal infection caused by ingestion of the bacterium Vibrio cholerae (V. cholerae). EU researchers elucidated the molecular mechanisms behind expression of virulence genes with important implications for new therapies.

Click "source" to read more.

"Inv... Read More

Fourth of July: American Presidents and Infectious Diseases

Happy Fourth of July! In honor of this historic holiday we’ve compiled a list showing how infectious diseases and vaccines have affected the lives of our most heralded leaders – the American presidents. These concise accounts are evidence that diseases can strike anyone, anywhere at any time, an... Read More
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