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MMP #6: A fused, single-subunit bacterial ribosome with Alexander Mankin and Michael Jewett

Host: Jeff Fox with special guest, Alexander Mankin and Michael Jewett.

Alexander Mankin –called Shura --of the University of Illinois, Chicago, and Michael Jewett at Northwestern University talk with Jeff Fox about their recent success in joining the 30S and 50S bacterial riboso... Read More

TWiM 131: Mice behaving badly

Michael and Vincent present Spotlights, brief reviews of classic papers in the Journal of Bacteriology, and explain how a single bacterial species can reverse autism-like social deficits in the offspring of obese mice.

Hosts: Vinc... Read More

Protein's "hands" enable bacteria to establish infection, research finds

When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the ... Read More

TWiM 73 Letters

Mark writes:

Hello Team TWiM,

I’ve followed with interest your coverage of Michael’s research into use of copper to fight hospital infection. Of all the interesting papers covered in 2013, I think the one most actionable is episode 55, The Copper Room. His res... Read More

BacterioFiles 215 - Plasmid Pirates Piezophile Particles

This episode: Deep-sea thermophile bacteriophage is pirated by another scurvy genetic element!

(10.2 MB, 11.2 minutes)

Show notes: 
J... Read More

The sorceress’s apprentice

ANYONE who walks in the woods will be familiar with witches’ brooms (pictured). Many trees sport these bushy tumours, which have a variety of causes. An important one is a group of bacteria called phytoplasma that are, in turn, carried from plant to plant by sap-sucking insects such as leafhoppe... Read More

TWiP 104: La maladie du sommeil

Michael returns to help the TWiP trio solve the case of the Delusional African Expatriate, who then discuss the association of natural and induced antibodies in mice with differential susceptibility to secondary cystic echinococcosis.

Hosts:  Read More

How small genetic change in Yersinia pestis changed human history

CHICAGO -- While studying Yersinia pestis, the bacteria responsible for epidemics of plague such as the Black Death, Wyndham Lathem, Ph.D., assistant professor in microbiology-immunology at Northwestern University Feinberg School of Medicine, found a single small genetic change that fundamentall... Read More

TWiV 373: The distinguished virology career of Julius S. Youngner


Host: Vincent Racaniello 

Guest: Julius S. Youngner

Vincent... Read More

TWiM #129: Dried and wrinkled, smooth and mucoid

The arrival in the US of plasmid-mediated resistance to colistin antibiotics, a last line of defense against many gram-negative bacilli, and a quorum sensing system in a eukaryote are topics of this episode hosted by Vincent, Michael, and Michele.

Image (right): Etest used to determin... Read More

TWiV 276: Ramblers go viral

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

 Host: Vincent Racaniello

Guests: Read More

Zika virus: Approaching the unknown

Understanding the scale and range of neurological disease associated with Zika virus infection is an urgent priority, warn researchers from the University of Liverpool's Institute of Infection and Global Health. Read More

TWiV 363: Eat flu and dyad

Hosts: Vincent RacanielloAlan Dove Read More

Pathogen grows on cold smoked salmon by using alternative metabolic pathways

Washington, DC - August 4, 2015 - The pathogen, Listeria monocytogenes grows on refrigerated smoked salmon by way of different metabolic pathways from those it uses when growing on laboratory media. The research could lead to reduced incidences of food-borne illness and death, said principal inv... Read More

BacterioFiles 252 - Small Cells Supervise Circadian Cycles

This episode: In mice, high-fat diets affect their gut microbes, which in turn disrupts their circadian cycles and metabolic health!

(8.6 MB, 9.35 minutes)

Show notes: 
Read More

TWiP 105: Survival of the fattest

The TWiPanosomes solve the case of the Young Man from Anchorage, and discuss how cestode parasites increase the resistance of brine shrimp to arsenic toxicity.

Hosts: Vincent Racaniello Read More

Better Chocolate with Microbes

For decades, researchers have worked to improve cacao fermentation by controlling the microbes involved. Now, to their surprise, a team of Belgian researchers has discovered that the same species of yeast used in production of beer, bread, and wine works particularly well in chocolate fermentati... Read More

Amoeba Takes Bites of Human Cells to Kill Them

Amoebae — a group of amorphous, single-celled organisms that live in the human body — can kill human cells by biting off chunks of intestinal cells until they die, a new study finds. This is the first time scientists have seen this method of cell killing, and the new findings could one day help ... Read More

TWiV 369: Camel runny noses and other JNK

Hosts: Vincent RacanielloAlan Dove, and Kathy Spindler

<... Read More

Host Biology in Light of the Microbiome: Ten Principles of Holobionts and Hologenomes

Link: http://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1002226

Groundbreaking research on the universality and diversity of microorganisms is now challenging the life sciences to upgrade fundamental theories that once seemed untouchable. To fully appreciate the change that... Read More
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