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Scientists unravel elusive structure of HIV protein

COLUMBIA, Mo. - HIV, or human immunodeficiency virus, is the retrovirus that leads to acquired immunodeficiency syndrome or AIDS. Globally, about 35 million people are living with HIV, which constantly adapts and mutates creating challenges for researchers. Now, scientists at the University of M... Read More

BacterioFiles 217 - Fungus Fortifies Fly Food

This episode: Fruit flies have microbes that help them get more nutrition out of low-quality food!


(8.4 MB, 9.1 minutes)


Show notes: 
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TWiV 294: Smallpox and anthrax and flu, oh my!

The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members.


Hosts:  Read More

BacterioFiles 218 - Parasitoids Pass Protective Prokaryotes

This episode: Parasitoid wasps spread helpful bacterial symbionts between their whitefly prey!


(10.9 MB, 11.9 minutes)


Show notes: 
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TWiP 107: Parasites leave a bad taste in my gut

The TWiPtastic trio solves the case of the Surfer from Switzerland, and reveal how taste-chemosensory tuft cells in the gut regulate immune responses to parasites.


Hosts: Vincent Racaniello,&n... Read More

TWiM #126: I’m not scared of zebrafish and mice and bears (oh my!)

The microbiome of hibernating bears, and zebrafish as a model for bacterial sepsis feature in this animal-centric episode of TWiM hosted by Vincent, Michael, and Michele.


Image: Bright-field (top) and fluorescent (bottom) images of zebrafish embryos infected with E. coli strain F11. E... Read More

BacterioFiles 243 - Fungal Friends Facilitate Phytoextraction (feat. Cat Adams)

This episode: A conversation with Cat Adams about how fungi help plants clean up toxic zinc nanoparticles in soil!


(14.6 MB, 16 minutes)


Show notes: 
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TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

BacterioFiles 210 - Archaea Acquired Alternative Abilities

This episode: Genes taken from bacteria may have been important for the evolution of distinct groups of archaea!


(7.4 MB, 8 minutes)


Show notes: 
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BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!


(7 MB, 7.5 minutes)


When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

The sorceress’s apprentice

ANYONE who walks in the woods will be familiar with witches’ brooms (pictured). Many trees sport these bushy tumours, which have a variety of causes. An important one is a group of bacteria called phytoplasma that are, in turn, carried from plant to plant by sap-sucking insects such as leafhoppe... Read More

TWiV 262: Wrong form, right professor

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Host: Vincent Racaniello


Guest: Read More

TWiV 370: Ten out of 15

Hosts: Vincent RacanielloAlan Dove, and Kathy Spindler


<... Read More

TWiV 362: Gotta catch 'em all

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

TWiV 305: Rhymes with shinola

Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States.


Hosts:  Read More

How small genetic change in Yersinia pestis changed human history

CHICAGO -- While studying Yersinia pestis, the bacteria responsible for epidemics of plague such as the Black Death, Wyndham Lathem, Ph.D., assistant professor in microbiology-immunology at Northwestern University Feinberg School of Medicine, found a single small genetic change that fundamentall... Read More

BacterioFiles Micro Edition 155 - Cells Save Superannuated Sequences

This episode: Bacteria are able to incorporate DNA from the environment into their genomes, even if it's thousands of years old!


(9.6 MB, 10.5 minutes)


Show notes: 
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TWiP 68 letters


Tim writes:


I listened to the latest TWIP this morning. Dickson mentioned the herbicide atrazine but thought it was a fungicide. It is actually a herbicide in the photosynthesis inhibitor class. Another bit of trivia about ag chemicals is that old chemicals like ... Read More

ASM Live at #ICAAC / ICC - Monitoring the Microbiome in Leukemia Patients Could Reduce Infections During Chemotherapy

Jessica Galloway-Peña, Ph.D., fellow in the Department of Infectious Diseases, Infection Control and Employee Health at The University of Texas MD Anderson Cancer Center and her colleagues have shown that disruption of the microbiome by illness or the administration of therapeutics can often lea... Read More

Protein's "hands" enable bacteria to establish infection, research finds

When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the ... Read More
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