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TWiM 111 Letters


Noah writes:


Dear Dr. Schaechter,


First off, I want to thank you for the effort you and your colleagues have invested in Small Things Considered and the podcast TWIM.  Back when I had a longer commute to work, I listened more religiously than now, wh... Read More

The sorceress’s apprentice

ANYONE who walks in the woods will be familiar with witches’ brooms (pictured). Many trees sport these bushy tumours, which have a variety of causes. An important one is a group of bacteria called phytoplasma that are, in turn, carried from plant to plant by sap-sucking insects such as leafhoppe... Read More

TWiM #122: Mayonii, microRNAs and the microbiome

Hosts: Vincent Racaniello, Michele Swanson, and Michael Schmidt.


Vincent, Michele, and Michael reveal the discovery of a new species of the spirochaete that causes Lyme disease, and fecal microRNAs that shape the gut microbiome. Read More

BacterioFiles 206 - Mollusc Maneuvers Microbe Machines to Macerate Maples

This episode: When digesting wood, shipworms outsource their microbial symbionts from gut to gills!


(9.7 MB, 10.6 minutes)


Show notes: 
Journal Paper<... Read More

TWiV 291: Ft. Collins abuzz with virologists

Vincent, Rich, and Kathy and their guests Clodagh and Ron recorded this episode at the 33rd annual meeting of the American Society for Virology at Colorado State University in Ft. Collins, Colorado.


Hosts: ... Read More

TWiP 95 letters

Ruben writes:


Dear Day-Twippers,


I am a big fan of TWIP. You do so many things right, that a little problem in your TWiP94 broadcast is not a big deal. As you may already know all three drugs in the Nutman et al. study are small molecules, not monoclonals, the... Read More

BacterioFiles 214 - Cable-Chlorophyte Coop Conducts Current

This episode: Cable bacteria and algae set up electric grid in sediments!


(6 MB, 6.5 minutes)


Show notes: 
Journal Paper


Read More

TWiV 361: Zombie viruses on the loose

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

BacterioFiles Micro Edition 147 - Clostridium Conquers Colleagues

This episode: Non-pathogenic Clostridium difficile strains can protect hamsters against their disease-causing bacterial siblings!


(7 MB, 7.5 minutes)


When hamsters were colonized with toxin-free strains of C. difficile, they were better able to resist infection b... Read More

TWiV 294: Smallpox and anthrax and flu, oh my!

The TWiV team reviews the discovery of old vials of smallpox virus at NIH, anthrax and influenza mishaps at CDC, the baby who was not cured of HIV, Cambridge Working Group, and sacking of NSABB members.


Hosts:  Read More

How small genetic change in Yersinia pestis changed human history

CHICAGO -- While studying Yersinia pestis, the bacteria responsible for epidemics of plague such as the Black Death, Wyndham Lathem, Ph.D., assistant professor in microbiology-immunology at Northwestern University Feinberg School of Medicine, found a single small genetic change that fundamentall... Read More

TWiV 358: Virology and proteomics with Ileana Cristea

Host: Vincent Racaniello


Guest: Ileana Cristea


Vincent meets up with Ileana at Princeton University to talk abou... Read More

TWiV 357: Mistletoe and the Tree of Life

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiP 69 letters


Richard writes:


Hi Vincent and Dickson,


I enjoy TWIP, and often recommend it to my students. I'm a parasitologist, primarily a Leishmaniac, but I have learnt a lot from TWIP. I find it both more educational and entertaining than Car Talk.


The disc... Read More

TWiM #121: A plague of pathogens

Filmed live at ASM Biodefense 2016 with special guests: Rebekah Kading and Wyndham Lathem.


Fr... Read More

TWiV 375: Zika and you will find

Hosts: Vincent RacanielloAlan DoveRich Condit Read More

TWiV 262: Wrong form, right professor

Unable to embed Rapid1Pixelout audio player. Please double check that:  1)You have the latest version of Adobe Flash Player.  2)This web page does not have any fatal Javascript errors.  3)The audio-player.js file of Rapid1Pixelout has been included.

Host: Vincent Racaniello


Guest: Read More

TWiV 364: It's not SARS 2.0

Hosts: Vincent Racaniello Read More

BacterioFiles Micro Edition 155 - Cells Save Superannuated Sequences

This episode: Bacteria are able to incorporate DNA from the environment into their genomes, even if it's thousands of years old!


(9.6 MB, 10.5 minutes)


Show notes: 
Read More

SIV shrugs off antibodies in vaccinated monkeys

New research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine only needs to stimulate moderate levels of antibodies that neutralize the virus. Read More
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