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Evidence for influenza H5N1 infections in humans

The fatality rate for human infections with avian influenza H5N1 is widely quoted at >50%, based on the number of deaths among the fewer than 600 cases confirmed by the World Health Organization. Wang, Parides, and Palese suggest that this number is an overestimate. Read More

TWiV 168 Letters

Mike writes:


Hello Men (and sometimes women) of TWiV!


I have read before that the human genome contains the genetic code of several thousand retroviruses. These retroviruses are in an inactive state, and are believed to be the product of infec... Read More

Epidemic bacteria can damage mucins to enter and infect a body part

Scientists from the Schepens Eye Research Institute, a subsidiary of Mass. Eye and Ear and affiliate of Harvard Medical School, have found for the first time that a bacterial pathogen can literally mow down protective molecules, known as mucins, on mucus membranes to enter and infect a part of t... Read More

TWiM 36: Domesticating a pathogen

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Hosts: Vincent Racaniello, Read More

TWiV 181: ORFan poxviruses and nIRFing prions

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Hosts: Vincent Racaniello, Rich Condit, and Read More

3% patients’ bacteria samples show total resistance (India)

In a worrisome finding, an ongoing survey at Sassoon hospital reveals that three per cent of bacterial infections in samples collected from patients over the past two-three months show total resistance to antibiotics.

Th study showed that three per cent of microbiologically confirmed infectio... Read More

TWiV 180: Throwing IFIT at flu and holding a miR to HCV

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Hosts: Vincent Racaniello, Alan Dove, and  Read More

BacterioFiles Micro Edition 85 - Pathogen Partitions Parasitoid Populations

This episode: A virus influences the competition between two species of parasitoid wasp!



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Read More

Can viruses horizontally transfer genes co-packaged from one host to another?

It has long been known that viruses, in addition to their own genomes, encapsidate extraneous nucleic acids. Although this phenomenon has been verified in the prokaryotic world, in eukaryotes, the significance of these alternative nucleic acids could just be trivial, or, quite possibly evolutio... Read More

C-section babies at higher risk of obesity

Babies delivered by caesarean are at a higher risk of becoming overweight or obese because they are not exposed to protective bacteria in the mother's vagina, international research has found.

The research, conducted by the Finnish paediatrician Erika Isolauri and to be presented in Sydney to... Read More

Beat Spring Allergies with Bacteria

It may sound odd that bacteria can actually reduce allergy symptoms. But, certain bacteria can reduce inflammation in the body, improve nutrient absorption, and reduce nasal and sinus symptoms linked to allergies. Of course, not just any bacteria will do.

Research by scientists at the Osaka ... Read More

Deadly infection claims San Francisco VA lab worker

State and federal health officials are investigating how a rare and virulent bacteria strain appears to have killed a young researcher at a VA Hospital's infectious diseases lab in San Francisco, setting off alarms that the man's friends and fellow researchers also may have been exposed.

The ... Read More

Dairy Researchers Identify Bacterial Spoilers in Milk

Our days of crying over spoiled milk could be over, thanks to Cornell food scientists.

Milk undergoes heat treatment -- pasteurization -- to kill off microbes that can cause food spoilage and disease, but certain bacterial strains can survive this heat shock as spores and cause milk to curdle... Read More

Climate Change Alters Soil Bacteria Distribution (podcast)

When we think about global warming, we tend to fret about things we can see: plants, animals, the polar ice caps. But the effects of climate change may go much deeper: into the earth itself. Because a new study shows that temperature controls where soil-dwelling microbes live. The findings are i... Read More

TWiV 193: Live at ASV in Madison

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Hosts: Vincent Racaniello, Rich Condit, Read More

TWiV 174: Dog runs and mooing miRs

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Hosts: Vincent RacanielloAlan Dove, and  Read More

H5N1 facts, not fear

Peter Palese and Taia Wang have written a compelling article that uses scientific facts to address the controversy over publication of research involving transmission of avian influenza H5N1 in ferrets. In response to calls in the media to destroy the viruses, curtail the research, and protect t... Read More

Synthetic Biology Expands Beyond Bacteria

Synthetic biology is getting a boost. So far, most researchers have designed their synthetic circuits using transcription factors found in bacteria. However, these don’t always translate well to nonbacterial cells and can be a challenge to scale. Now, researchers have come up with a new method t... Read More

TWiV 174 Letters

Mark writes:


Hi TWIVers,


I love your podcast! I am a postdoc in Joe DeRisi's lab at UCSF and I know that right now I am supposed to be aiming for a faculty job. But my real goal is to discover something cool enough to end up on TWIV.


A... Read More

More evidence for mild influenza H5N1 infections

Influenza H5N1 virus frightens many because of the widely quoted case fatality ratio of >50%, which is based on the number of deaths among the fewer than 600 cases confirmed by the World Health Organization. Such fear is misguided, because it is likely that the fatality ratio is far lower. For e... Read More

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