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ICAAC 2014 - New Antimicrobial Strategy Silences NDM-1 Resistance Gene in Pathogens

Researchers have created a synthetic DNA analog that can bind to and silence the gene responsible for NDM-1, a severe form of antibiotic resistance that can make ... Read More

TWiM 98 Letters

 


Patrick writes:


Hi Vincent,


I thought you and the rest of the TWiM/TWiP folks would be interested in the following paper: Transferred interbacterial antagonism genes augment eukaryotic innate immune function, published online in Nature this week... Read More

Too exhausted to fight -- and to do harm

An 'exhausted' army of immune cells may not be able to fight off infection, but if its soldiers fight too hard they risk damaging the very body they are meant to be protecting, suggests new research from the University of Cambridge. Read More

Protein's "hands" enable bacteria to establish infection, research finds

When it comes to infecting humans and animals, bacteria need a helping hand.

Kansas State University biochemists have found the helping hand: groups of tiny protein loops on the surface of cells. These loops are similar to the fingers of a hand, and by observing seven individual loops on the ... Read More

TWiV 379: A mouse divided

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiP 109: Blame it on Mother

Daniel and Vincent solve the case of the Truck Driver from India, discuss why parasites resistant to an antimalarial drug are not transmitted by mosquitoes, and introduce Paul who presents a new case study.


Hosts:  Read More

TWiV 305: Rhymes with shinola

Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States.


Hosts:  Read More

Vitamin A supplementation may cause the immune system to 'forget' past infections

Although vitamin A supplementation can have profound health benefits when someone is deficient, new evidence is emerging to show that vitamin A supplementation above and beyond normal levels may have negative health consequences. A new research report published in the July 2015 issue of the Jour... Read More

MMP #7: A virtual robot with its own virtual microbiome telling it what to do with Warren C. Ruder

Host: Jeff Fox with special guest, Warren C. Ruder.


Warren C. Ruder of Virginia Polytechnic Institute and State University (Virginia Tech) in Blacksburg, Virginia talks with Jeff Fox about efforts to develop an electronic model system that incorporates a robot for a host and two sligh... Read More

TWiP 85 letters

 


Jan writes:


Dear Sirs


This is fun, and although I'm sure someone will gripe about Dicksons enthusiastic response to the crayfish, it made my life easier. I think it's Paragonimus kellicoti. As for eating raw crayfish; how drunk... Read More

TWiM 119 Letters

Jeanne writes:


Dear TWiM,
 
With regard to the question about culturing gut microbes from Drosophila:
 
I was lucky enough to take a sabbatical in the lab of Dr. Angela Douglas (http://angeladouglasl... Read More

TWiV 386: The dolphins did it

Hosts: Vincent RacanielloRich Condit, and  Read More

MMP #10: Examining the gut microbiota of American Indians of Cheyenne and Arapaho ancestry.

Host: Jeff Fox with special guests, Cecil M. Lewis, Jr. and Krithivasan Sankaranarayanan.


Lewis and Krithivasan Sankaranarayanan—“Krithi”-- both fro... Read More

TWiM 97 Letters


Dennis writes:
hi Doc,


A paper just published in nature:


http://www.nature.com/nature/journal/vaop/ncurrent/pdf/nature14098.pdf


reports an effective antibiot... Read More

ASM Live at #ICAAC / ICC - Monitoring the Microbiome in Leukemia Patients Could Reduce Infections During Chemotherapy

Jessica Galloway-Peña, Ph.D., fellow in the Department of Infectious Diseases, Infection Control and Employee Health at The University of Texas MD Anderson Cancer Center and her colleagues have shown that disruption of the microbiome by illness or the administration of therapeutics can often lea... Read More

TWiV 380: Viruses visible in le microscope photonique

Hosts: Vincent RacanielloDickson DespommierAlan Dove Read More

TWiV 385: Failure

Hosts: Vincent Racaniello and Dickson Despommier


Guest: Stuart Firestein Read More

TWiM #134: Lipids that live forever

Design of a synchronously lysing bacterium for delivery of anti-tumor molecules in mice, and hopanoids, the lipids that live forever, brought to you by the four Microbies of TWiM.


Hosts: Vincent Racaniello, Elio Schaechter,... Read More

Bacterial enzyme may help people quit smoking

Current smoking cessation aids fail in 80 to 90 percent of smokers. The idea behind this therapy would be to destroy nicotine before it reaches the brain—depriving a person of the “reward” of nicotine that can trigger relapse into smoking. Pseudomonas putida, a bacterium typically found in tobac... Read More
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