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CDC reports two more novel flu infections

The US Centers for Disease Control and Prevention (CDC) today confirmed two more novel flu infections, one an H3N2 variant that has been identified in 11 other patients this year and one an H1N1 variant that has never been reported in humans before.

The CDC described the latest novel H3N2 cas... Read More

RNA virus packaging specificity explained?

In 1969 David Baltimore proposed that poliovirus RNA replication is coupled with packaging, in that only those genomes actively replicating will be selectively encapsidated. From an evolutionary standpoint, it is an ingenious requirement to ensure that only virus genomes capable of replication ... Read More

Microbes Go Rafting on Floating Volcanic Rocks

Volcanoes bring death and destruction, but out of the ashes life soon finds fertile ground. A unique experiment is sifting through floating debris from an ongoing volcanic event to see how microbes move in. The results may help in assessing a recent hypothesis that the first life forms may have ... Read More

India polio-free for one year

A year has passed since the last reported case of poliomyelitis in India, which occurred on 13 January 2011 in a two year old girl in Howrah, West Bengal. Read More

TWiV 188 Letters

Judi writes:


To our TWIV leaders!


If you have a mac with Apps, please go to the app store and download cell images.... I think you'll have a great time going through them.


One other thing - I listened to your show on science reform with interest but I ... Read More

E. coli: can subtractive reverse vaccinology help design a vaccine?

Escherichia coli is no stranger to the human body. In around 20% of us, E. coli is the predominant species in our gastrointestinal tract, where it lives as a commensal. But when E. coli gets out of hand it can cause anything from gastroenteritis to sepsis to urinary tract infections. It's those ... Read More

New study maps hotspots of human-animal infectious diseases and emerging disease outbreaks

A new global study mapping human-animal diseases like tuberculosis (TB) and Rift Valley fever finds that an "unlucky" 13 zoonoses are responsible for 2.4 billion cases of human illness and 2.2 million deaths per year. The vast majority occur in low- and middle-income countries.

The report, wh... Read More

Policy On High-Risk Biological Research Tightened

The Obama administration has announced a new policy to handle the risks posed by legitimate biological research that could, in the wrong hands, threaten the public.

The move comes in response to a huge debate over recent experiments on bird flu virus that got funding from the National Institu... Read More

Human Response to Bacterial Infection and Resolution in Mice, Simulated

Reporting in the Proceedings of the National Academy of Sciences, a team of Jefferson immunologists found that a specialized "human immune system" mouse model closely mimics a person's specific response and resolution of a tick-borne infection known as relapsing fever, caused by the bacteria Bor... Read More

The Microbiology of Speciation

The fields of microbial symbiosis and speciation have achieved astonishing advances during the past two decades, yet symbiosis and speciation are not commonly discussed together and can seem to be odd partners in their capacity to operate synergistically in nature. Indeed, microbial symbiosis is... Read More

Anrtibiotics Breed Drug-Resistant Bacteria In Pigs

After giving pigs a low-dose of antibiotics for just two weeks, researchers detected a drastic rise in the number of E. coli bacteria in the guts of the animals. And those bacteria showed a large jump in resistance to antibiotics.

The particular strain of E. coli detected in the study was not... Read More

Study upholds immune system’s role in autism

Changes in an overactive immune system can contribute to autism-like behaviors in mice, new research shows.

Scientists at the California Institute of Technology (Caltech) pioneered the study of the link between irregularities in the immune system and neurodevelopmental disorders such as auti... Read More

Radio Mycelium Tutorial (fungal hacking workshop in Brussles)

Radio Mycelium proposes the construction of a series of experimental situations examining a new networked imaginary, the single organism of the fungal mycelium, in relation to pathogenic, electromagnetic communications. Participants will learn how to construct simple measurement devices, and cul... Read More

Titan's tides reveal hidden ocean that could host life

Alien hunters take note: a global water ocean potentially bigger than all those on Earth combined, is sloshing beneath Titan's icy crust.

Combined with the cocktail of organic chemicals already known to exist on Titan, abundant water could make the moon prime real estate for life – though mor... Read More

Kids Have Little Protection from New Flu Virus

Children younger than 10 likely will be the most susceptible if a variant of the influenza A (H3N2) virus -- dubbed A (H3N2)v -- develops the ability to transmit easily among humans, researchers found.

Since August 2011, there have been 12 cases of infection with the variant -- which contains... Read More

Worse Fears Realized? Completely Drug Resistant TB has emerged in India

Extensively Drug Resistant (XDR) Mycobacterium tuberculosis (MTB) was first encountered in 2006. Now as we enter 2012 we learn that a strain of MTB totally resistant (TDR) to all current antimicrobials has entered the Indian sub-continent . This new strain to India, TDR-MTB first emerged in ... Read More

Bacteria-Killing Viruses Wield an Iron Spike

Forget needles in haystacks. Try finding the tip of a needle in a virus. Scientists have long known that a group of viruses called bacteriophages have a knack for infiltrating bacteria and that some begin their attack with a protein spike. But the tip of this spike is so small that no one knew w... Read More

Life's Most Amazing Invisible Secrets

One of my heroes, evolutionary microbiologist Lynn Margulis, died this past Thanksgiving. She was an amazing lady who was married to Carl Sagan for many years, and partnered with James Lovelock in discovering that the earth is an interconnected living global ecosystem run largely by microbes. Sh... Read More

Friendly Fungi: Elucidating the fungal biosynthesis of stipitatic acid

In a tale worthy of Sherlock Holmes, scientists in the School of Chemistry at the University of Bristol, UK have solved a biochemical mystery that had previously proven elusive for 70 years: How the fungus Talaromyces stipitatus produces stipitatic acid (6), which is a tropolone, one of an atypi... Read More

Bacteria that could pass as X-men: part 2

'Second part of my thinly veiled excuse to research X-men and call it work. The first post can be found here. This is only meant to be a two-parter but I’ll see how I feel on Monday, and whether I can find any more X-men that are as amazing as bacteria.'

4) Multiple Man

Multiple Man’s powe... Read More

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