Scientists at Stanford University and the J. Craig Venter Institute have developed the first software simulation of an entire organism, a humble single-cell bacterium that lives in the human genital and respiratory tracts.
The scientists and other experts said the work was a giant step towar... Read More
The epidemiology episode with Michael Walsh was great. I loved the philosophical detour into counterfactual statements, time travel, and the meaning of causation. TWiV may indeed be viral, but from listening to it I fee... Read More
In a tale worthy of Sherlock Holmes, scientists in the School of Chemistry at the University of Bristol, UK have solved a biochemical mystery that had previously proven elusive for 70 years: How the fungus Talaromyces stipitatus produces stipitatic acid (6), which is a tropolone, one of an atypi... Read More
In the search for new life, scientists have studied the depths of the ocean and the lips of steaming volcanoes. They've looked on Mars and the moons of Jupiter, and even planets beyond this solar system.
Dr. David Relman went searching inside his own mouth. On a routine dental visit in 1998, ... Read More
Norton Zinder made two important discoveries in the field of virology. While a Ph.D. student with Joshua Lederberg at the University of Wisconsin-Madison he found that viruses of bacteria (bacteriophages) could move genes from one host to another, a process called transduction. Later in his own ... Read More
The acquired immunodeficiency syndrome (AIDS) pandemic is caused by the human immunodeficiency virus (HIV-1), which attacks the immune system and leaves infected individuals susceptible to opportunistic infections. AIDS and HIV-1 are thought to have a relatively short history in humans, with the... Read More
As the world’s athletes limber up for the forthcoming Olympic games in London, infectious-disease experts are preparing for their own trials. Their competition is with the diseases that millions of athletes, officials, media and spectators bring with them as they converge from across the globe o... Read More
We are surrounded by bacteria, viruses, fungi and parasites. The fact that we nevertheless do not fall prey to infections is thanks to certain cellular sensor molecules such as toll-like receptors (TLR), which recognize the molecular structure of pathogens and intercede by ensuring an often comp... Read More
Better resistance to parasites and a less fussy diet are allowing aggressive signal crayfish from the US to threaten white-clawed crayfish native to Yorkshire.
The Yorkshire crayfish suffers from two parasites: plague, which is carried by the American invader, and porcelain disease that makes... Read More
An investigation led by UCSF has found that the risk of female-to-male HIV transmission is increased three fold for women with bacterial vaginosis, a common disorder in which the normal balance of bacteria in the vagina is disrupted.
The new research assessed the association between bacterial... Read More
The second of two papers on avian influenza H5N1 virus that caused such a furor in the past year was published today in the journal Science. I have carefully read the paper by Fouchier and colleagues, and I assure you that it does not enable the production of a deadly biological weapon. The resu... Read More
Manmade climate change is the main driver behind the unexpected emergence of a group of bacteria in northern Europe which can cause gastroenteritis, new research by a group of international experts shows.
The paper, published in the journal Nature Climate Change on Sunday, provided some of th... Read More
In a French meadow, a creature that specialises in corrupting the bodies of other animals is getting a taste of its own medicine.
Leptopilina boulardi is a wasp that lays its eggs in fly maggots. When the wasp grub hatches, it devours its host form the inside out, eventually bursting out of its... Read More
It may not be the latest style in bovine bling, but researchers at Princeton University say a golden tattoo attached to a cow’s tooth could one day tell you something about your health.
The remote sensing device has the ability to detect a single bacterium, and to demonstrate, scientists at P... Read More
Advances in the 1950s and 1960s, including unprecedented cooperation between Soviet and U.S. scientists, allowed polio to be eradicated throughout the Americas by 1994 and all of Europe in 1998. Eliminating the crippling scourge has been more difficult, however, in some parts of Africa and Asia.... Read More
The HPV vaccine not only has resulted in a decrease in human papillomavirus infection in immunized teens but also in teens who were not immunized.
The study is believed to be the first to show a substantial decrease in HPV infection in a community setting as well as herd protection -- a decre... Read More
Cell death, also known as apoptosis, is a significant part of normal animal development. However, the question arises whether bacteria, similar to higher organisms, have a built-in mechanism that determines when the cells die.
Researchers at the Hadassah Medical School of the Hebrew Universi... Read More
India has been free of polio for over one year. This is a remarkable accomplishment, considering that just 30 years ago the country recorded 200,000 cases of the disease annually, or one every three minutes. With polio endemic in two neighboring countries, Pakistan and Afghanistan, and in the mo... Read More
The more controversial of two papers describing how the lethal H5N1 bird flu could be made easier to spread was published on Thursday, six months after a scientific advisory board suggested that the papers’ most potentially dangerous data be censored.
The paper’s publication, in the journal S... Read More
Bacterial genomes differ dramatically in size: from 140Kb to 13Mb (those numbers might be off now...please let me know if something has broken the record. Yes, I know the lower estimate can change based on semantics, but there are a bunch in that range). Although we have some clues as to how sel... Read More