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TWiP 40 Letters

David writes:

Love the TWIPs! I'm a helminth user (25 hookworm for allergies), so your programs are fascinating!


Dr. Racaniello, after listening to TWIP 33 where you were discussing the history of your surname, I thought I'd give your listeners a way to remember you... Read More

TWiV 187: The mummy



Hosts: Vincent Racaniello and Rich Condit


Vincent and Rich discuss recovery ... Read More

Avian Influenza A (H5N1) virion

This transmission electron micrograph (TEM), taken at a magnification of 150,000x, revealed the ultrastructural details of an avian influenza A (H5N1) virion, a type of bird flu virus which is a subtype of avian influenza A. At this magnification, one may note the stippled appearance of the roug... Read More

Gut bacteria ‘biome’ differs in obese people

For the first time, the vast array of bacteria in the human gut has been studied as a complex, integrated biological system, rather than a set of separate species.

The new approach, which reveals patterns that correspond with body weight, treats the human microbiome as a cohesive “supra-organ... Read More

Clostridium difficile: Emerging Issues and Treatments #ICAAC (Video)

Clostridium difficile infection is an important cause of intestinal disease, primarily affecting hospitalized patients exposed to antibiotics. Infection has been associated with prolonged hospital stays and excess healthcare expenditures.Recent changes in epidemiology of this disease show a rise... Read More

Stopping Dengue Fever With Bacteria and Math

It may be possible to eliminate the deadly dengue fever by infecting mosquitoes with a bacterium called Wolbachia that prevents the mosquitoes from transmitting the dengue virus to humans. A new mathematical model, developed by Nick Barton (Institute of Science and Technology, Austria) and Mich... Read More

One Health: Humans, Animals and the Environment

The health of humans, animals, and the environment are inextricably interconnected. Disruption of the environment often creates new niches for the evolution of infectious diseases, and provides opportunities for the transmission of pathogens to animals or humans. The majority of infectious disea... Read More

A Surprising Link Between Bacteria and Colon Cancer

Could bacteria be responsible for colon cancer? In papers published in the journal Genome Research, two research teams, working independently, describe a group of bacteria that are linked to higher rates of the disease.

Called Fusobacterium, this type of bacterium is very rarely found among ... Read More

The Latest News from the Human Microbiome Project

The NIH Human Microbiome Project has been a 5-year endeavor to produce community resources to support the field of human microbiome research. Although the HMP has already produced hundreds of peer-reviewed publications, in the past week 2 major HMP Consortium papers as well as 20+ companion pap... Read More

Microbial Colonization and the Host: Do the Colonists Reshape the Landscape?

Traditionally, colonization of a host has been described in terms of a microbial community that does not affect the host, but recent research (such as the Human Microbiome Project) suggests that colonizing microbes are having an effect not only on the host, but on each other. Participants discu... Read More

Why Science? Microbiology (video)

Explore Research at the University of Florida: Keith Schneider, an Associate Professor of Food Science and Human Nutrition at the University of Florida, explains what made him want to become a scientist originally, and what he enjoys about his career and research now. Read More

The Black Queen Hypothesis: how microbes lose a necessary function and survive to tell the tale

Pared down genomes are the norm in symbiotic microbes, but how do non-symbionts get away with cutting out functions it would appear that they need? The authors of an Opinion piece in mBio this week explain their ideas about the matter. They say microbes that shed necessary functions may well be ... Read More

TWiV 178: T-Sharp on how tequila mosquito



Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Read More

TWiV 177: Live in Dublin



Hosts: Vincent Racaniello, Connor Bamford, Read More

Bacteria Kamikazes

Researchers have constructed a new synthetic bacterium that detects Pseudomonas aeruginosa, a common microbe and a leading cause of hospital-acquired infections, and explodes, releasing antimicrobials that kill the invaders. The results, published today (August 16) in Molecular Systems Biology, ... Read More

Millions of germs fly when you enter the room

A person’s mere presence in a room can add 37 million bacteria to the air every hour, a new study finds.

The bacterial material is largely left behind by previous occupants and stirred up from the floor when someone enters.

“We live in this microbial soup, and a big ingredient is our own m... Read More

TWiV 192: Viral tertulia



Hosts: Vincent Racaniello, Alan Dove, and  Read More

TWiV 194: Five postdocs in North America



Hosts: Vincent Racaniello, Matthew Daugherty, Jondavid deJong, Hel... Read More

Antibiotic-Resistant Bacteria Linked to Seagulls in Miami Beach

Extended spectrum beta-lactamases (ESBL's) are enzymes that enable bacteria to resist multiple antibiotics. In the past few years ESBL-producing enteric bacteria (such as E. coli) have become an increasingly common cause of community acquired infections worldwide. The source of these organisms i... Read More

Fungi that steal genes from bacteria

In order to survive in complex and interesting environments in the wild, bacteria have a whole arsenal of chemical products that they make within the cell. These chemicals are used for signalling, defence and communication between bacterial cells. One particular group of these chemicals is calle... Read More

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