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Getting Started with MicrobeWorld

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Is brushing your teeth harming your gut microbiome?

In the 1960’s, the microbicide triclosan, was introduced in the United States, and soon after, human weight started to increase dramatically. For some time, researchers have wondered whether triclosan could have played a role in disrupting endocrine dysfunction and contributing to the obesity ep... Read More

TWiV 405: All the world's a phage

The TWiXers discuss a study on vertical transmission of Zika virus by Aedes mosquitoes, and uncovering Earth's virome by mining existing metagenomic sequence data.


Hosts: Vincent Rac... Read More

BacterioFiles 269 - Magnetic Microbes Maim MRSA

This episode: Killing pathogens by attaching magnetotactic bacteria to them and then raising the heat with magnetic fields!


(10.6 MB, 11.6 minutes)


Show notes: 


Journal Paper:
Chen C, Chen L, Yi Y, Chen C, Wu L-F, Song ... Read More

TWiV 414: Zika in the guys with Diamond

Michael Diamond visits the TWiV studio to talk about chikungunya virus and his laboratory's work on a mouse model of Zika virus, including the recent finding of testicular damage caused by viral replication.


Hosts:  Read More

TWiV 415: Ebola pipettors and the philosopher's clone

Jeremy, Aaron, and Ted join the TWiV team to discuss their work on identifying a single amino acid change in the Ebola virus glycoprotein from the West African outbreak that increases infectivity in human cells.


Hosts:  Read More

BacterioFiles 277 - Sailor Cells Store Selenium

This episode: Bacteria with their own magnetic compass can also clean up and recover toxic but valuable elements!


(6.1 MB, 6.7 minutes)


Show notes: 


Read More

Fungus Causing Fatal Infections in Hospitalized Patients Has Unique Growth Patterns

Washington, DC – August 17, 2016 – The multidrug-resistant yeast Candida auris, which has caused fatal infections in some hospitalized patients, has at least two different growth patterns and some of its strains are as capable of causing disease as the most invasive type of yeast called Candida ... Read More

Burkholderia multivorans evolves in bursts in the lungs of cystic fibrosis patients

Leonilde M. Moreira, PhD, has been studying the Burkholderia complex for 15 years. The bacteria, known for causing pneumonia or septicemia in some individuals, can survive for prolonged periods in moist environments. During the last 10 years, it has become one of the more predominant bacteria se... Read More

TWiV 413: Partnerships not Parachutes

From the EIDA2Z conference at Boston University, Vincent, Alan and Paul meet up with Ralph Baric, Felix Drexler, Marion Koopmans, and Stacey Schultz-Cherry to talk about discovering, understanding, protecting, and collaborating on emerging infectious diseases.


Hosts:  Read More

TWiV 402: The plight of the bumblebee

Polio returns to Nigeria, Zika virus spreads in Miami, and virus infection of plants attracts bumblebees for pollination, from the virus gentlepeople at TWiV.


Hosts: Vincent Racaniello Read More

Vibrio cholerae population structure changes in a matter of weeks

Although the Gram-negative bacterium Vibrio cholerae (right) is normally associated with human pathogenic disease, most V. cholerae cells spend their lives in an aquatic environment, and only a few of the many serotypes are able to cause disease. When strains acquire the right genetic makeup – s... Read More

MMP #16: Insights into Toxoplasma gondii parasites

Host: Jeff Fox with special guest, Emma Wilson.


Emma H. Wilson of the University of California, Riverside, talks with Jeff Fox about efforts, with her collaborators to determine more precisely how Toxoplasma gondii parasites disrupt the mammalian brain—in this case, the brains of mice... Read More

TWiM #141: Nutritional immunity and polymicrobial infections

Jennifer joins Vincent, Elio, and Michael to talk about the work of her laboratory on how a respiratory virus enhances bacterial growth by dysregulating nutritional immunity.


Hosts: Vincent Racaniello, ... Read More

BacterioFiles 268 - Sophisticated Cyanobacterium Sight

This episode: Spherical cyanobacterium Synechocystis acts like a tiny eyeball in sensing light, allowing cells to move closer to light sources!


(9.7 MB, 10.6 minutes)


Show notes: synSEM Read More

Investigators Map Genomes of Three Historically Important Zika Strains

Washington, DC - August 18, 2016 - A team of researchers from Utah State University, Logan, has characterized the consensus genome sequences of three historically important Zika virus strains. This work is an important step towards developing antiviral therapeutic and preventive strategies again... Read More

Carbapenem-resistant bacteria isolated from a pig farm in the United States

While carbapenems aren’t allowed to be given to feedlot animals, other beta-lactam antibiotics are. This is a large class of drugs that includes extended-spectrum cephalosporin drugs. There is no direct line between the use of these extended-spectrum cephalosporins and selection for carbapenem r... Read More

BacterioFiles 283 - Phages Furnish Photosynthetic Fortifications

This episode: Viruses infecting photosynthetic bacteria could transfer immunity to other viruses between their hosts!


(6.8 MB, 7.4 minutes)


Show notes: 


Read More

TWiM 135 Letters

Reed writes:


Dear Vincent, Elio, Michael, and Michelle,


I've just recently finished TWiM number 133 and wanted to comment about the use of the term "secondary metabolite" throughout the episode and often in the primary literature. Michael pointed out that a se... Read More

Zika virus in Brazilian non-human primates

Zika virus RNA has been detected in New World monkeys from the Northeast region of Brazil. This finding suggests that primates may serve as a reservoir host for the virus, as occurs in Africa. Read More

TWiM #144: Did eukaryotes invent anything?

The TWiMers discuss how changes in domestic laundering affect the removal of microorganisms, and assembly of a nucleus-like structure during viral replication in bacteria.


Hosts: Vincent Racaniello, Read More

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