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Biologist investigates how gene-swapping bacteria evade antibiotics

A scientific peek into bacteria boudoirs is revealing how "sex" among disease-causing microbes can lead different species or strains to become resistant to antibiotic medications. Read More

Sendai virus defends against a threat

A research group at Hiroshima University demonstrated the mechanism by which the Sendai virus (SeV) escapes the host immune system. The researchers examined the crystal structure of the complex of SeV C protein and transcription factor STAT1, and found that SeV C protein inhibits the signal tran... Read More

TWiV 385: Failure

Hosts: Vincent Racaniello and Dickson Despommier


Guest: Stuart Firestein Read More

Plague infected humans much earlier than previously thought

Plague infections were common in humans 3,300 years earlier than the historical record suggests, reports a study published October 22 in Cell. By sequencing the DNA of tooth samples from Bronze Age individuals from Europe and Asia, the researchers discovered evidence of plague infections roughly... Read More

NYU research: Severe liver damage in mid/late-adulthood among PWID with chronic HCV

The Hepatitis C virus (HCV) infection is a chronic blood-borne viral infection that affects an estimated 160 million people, or 2-3% of the population world-wide. Alarmingly, chronic HCV infection accounts for one-quarter of the cases of cirrhosis and hepatocellular carcinoma (HCC). If HCV is le... Read More

New smart drug targets and reduces site-specific inflammation

BEER-SHEVA, Israel...July 22, 2015 - Ben-Gurion University of the Negev (BGU) and University of Colorado researchers have developed a dynamic "smart" drug that targets inflammation in a site-specific manner and could enhance the body's natural ability to fight infection and reduce side effects. Read More

BacterioFiles 251 - Mycophagous Myrmicinae Mutualist Microbes

This episode: Gut bacteria seem to help ants with very restrictive diets flourish more!


(10.6 MB, 11.5 minutes)


Show notes: 
Journal Paper


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Study finds state policies influence vaccination, disease outbreak rates

Athens, Ga. - Lax state vaccination laws contribute to lower immunization rates and increased outbreaks of preventable diseases--like whooping cough and measles--according to a new study from the University of Georgia. Read More

New Drug for Lung Cancer can Improve the Survival Rate Greatly

BOC Sciences-Scientists have found a drug called nivolumab more effective for non-small cell lung cancer, as it increases the survival time while bring less side effects than the traditional drug used for non-small cell lung cancer. Read More

Portraits of Microbiologists Using Luminous Bacteria as "Paint."

My wife Jennifer Quinn​ hits it out the park: a portrait of Kenneth Nealson​ and the late Woody Hastings "painted" with luminous bacteria, giving them props for the early days of quorum sensing---where the basic principles were first uncovered in bioluminescent microbes. This principle of "aut... Read More

Study: Breastfeeding could reduce common infections among Indigenous infants

TORONTO, Aug. 17, 2015--Promoting breastfeeding could lead to a substantial reduction in common infections and even deaths that are more common in Indigenous infants than non-Indigenous infants, a new study suggests. Read More

Compound from Red Wine is Helpful to Slow the Development of Alzheimer

BOC Sciences-Alzheimer is one of the most common diseases among the elderly as aging playing a contributing role in the developing process of it. Recently scientists found a natural compound beneficial to slow down the deterioration and treatment of Alzheimer. At present a phase 2 study is carri... Read More

Transgenic pigs resistant to foot-and-mouth disease

Foot-and-mouth disease virus (FMDV) infects cloven-hoofed animals such as cattle, pigs, sheep, goats, and many wild species. The disease caused by this virus is a substantial problem for farmers because infected animals cannot be sold. Transgenic pigs have now been produced which express a short... Read More

ZIKA VIRUS ‘IS ABOUT AS SCARY AS IT GETS’

The Zika virus, unlike other mosquito-borne viruses such as dengue, has until now been relatively unknown and unstudied. Read More

TWiV 378: Herpes plays DUBstep

Hosts: Vincent RacanielloDickson DespommierAlan Dove, and  Read More

How long have primates been infected with viruses related to HIV?

Disease-causing viruses engage their hosts in ongoing arms races: positive selection for antiviral genes increases host fitness and survival, and viruses in turn select for mutations that counteract the antiviral host factors. Studying such adaptive mutations can provide insights into the distan... Read More

Rapid Ebola Test Could Play Key Role in Efforts to End Lingering Outbreak

Research presented at the 2015 AACC Annual Meeting & Clinical Lab Expo will expand on the studies that led to a fingerprick Ebola test becoming the first and only rapid diagnostic for this disease to receive approval from the World Health Organization (WHO). This test could prove vital to breaki... Read More

First hospital-based rapid detection Zika test now available

Collaboration between two Texas Medical Center institutions has resulted in today's release of the country's first hospital-based rapid tests for the Zika virus. Read More

TWiV 394: Cards in a hand

Vincent and Alan speak with Erica Ollmann Saphire about her career and her work on understanding the functions of proteins of Ebolaviruses, Marburg virus, and other hemorrhagic fever viruses, at ASM Microbe 2016 in Boston, MA.


Hosts:  Read More

A Green Thumb for Ocean Microbes

MIT-WHOI Graduate student Kristen Hunter-Cevera describes the challenges and obstacles involved with growing marine microbes (in her case, Synechococcus) in a laboratory setting, and outlines the value of her research in understanding marine biogeochemistry. Read More
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