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Dually noted: New CRISPR-Cas9 strategy edits genes 2 ways

The CRISPR-Cas9 system has been in the limelight mainly as a revolutionary genome engineering tool used to modify specific gene sequences within the vast sea of an organism's DNA. Cas9, a naturally occurring protein in the immune system of certain bacteria, acts like a pair of molecular scissors... Read More

'Clever adaptation' allows yeast infection fungus to evade immune system attack

Johns Hopkins Bloomberg School of Public Health researchers say they have discovered a new way that the most prevalent disease-causing fungus can thwart immune system attacks. Read More

Study: Breastfeeding could reduce common infections among Indigenous infants

TORONTO, Aug. 17, 2015--Promoting breastfeeding could lead to a substantial reduction in common infections and even deaths that are more common in Indigenous infants than non-Indigenous infants, a new study suggests. Read More

Bacterial melanin can replace Non-steroidal anti-inflammatory drugs (NSAIDs) in arthritis treatments

Melanin produced by a marine bacteria Bacillus spp. has shown shown to have good anti-inflammatory activity. The pigment had shown to inhibit inflammatory enzymes cycloxygenase, lipooxygenase, myeloperoxide,NO synthase in vitro at a concentration which was non-cytotoxic..This will be a breakthro... Read More

Kicking latent HIV: New strategies to reactivate reservoirs of latent infection

In cells with latent HIV infection, the virus is dormant, and such cells are therefore not attacked by the immune system or by standard antiretroviral therapy. To eradicate the virus from the human body and truly cure a patient, reservoirs of latently infected cells need to be activated and elim... Read More

Flu vaccine reduces hospitalizations and deaths among nursing home residents

When the influenza vaccine is well matched to the prevailing strains of flu in a given season, patients in nursing homes are significantly less likely to be hospitalized or to die of pneumonia and other influenza related causes. The finding comes from a study of more than 1 million Medicare fee-... Read More

Harmless bacteria may be helpful against meningococcal outbreaks

Nasal drops of harmless bacteria can inhibit a related bug that sometimes causes meningococcal disease, according to new findings published online in Clinical Infectious Diseases. The study--conducted among college students, a group at higher risk for this often serious illness--suggests a new a... Read More

Researchers Find Novel Signature in the Brains of Children with Cerebral Malaria: Disease exacerbated by HIV

Washington, DC - September 22, 2015 - Cells associated with inflammation and blood clotting accumulate in the brain blood vessels of children affected by a potentially fatal form of malaria called cerebral malaria (CM), potentially contributing to the disease process, an international team of re... Read More

Strategies to decrease bacterial colonization

Among the bacterial infections that are most difficult to treat, chronic infections associated with bacterial biofilms are one of the most hazardous. Bacterial biofilms are densely packed communities of microbial cells surrounded with secreted polymers. In her doctoral thesis, chemist Shoghik Ha... Read More

NYU researchers observe upward trend in hepatitis C infection rates among HIV+ MSM

While sexual contact is not the most efficient means of hepatitis C (HCV) transmission, there have been several reports of outbreaks of sexually transmitted HCV in HIV-positive men who have sex with men (MSM). HCV infections are more likely to become persistent and to lead to progressive liver d... Read More

Safer, with more benefits: Parents' vaccine views shifting

ANN ARBOR, Mich. -- Over the same time period that multiple outbreaks of measles and whooping cough made headlines around the country, parents' views on vaccines became more favorable, according to a new nationally-representative poll. Read More

Ebola virus mutations may help it evade drug treatment

Genetic mutations called "escape variants" in the deadly Ebola virus appear to block the ability of antibody-based treatments to ward off infection, according to a team of U.S. Army scientists and collaborators. Their findings, published online this week in the journal Cell Reports, have implica... Read More

Improved survival of HIV patients facilitates heart disease research

WASHINGTON (July 27, 2015) - The improved survival rate of HIV patients in sub-Saharan Africa due to effective treatment programs is increasing the ability of researchers in Africa to study the impacts of cardiovascular disease in HIV patients, according to a guest editor page published today in... Read More

Oysters harbor, transmit human norovirus: Avoid raw ones

Washington DC - August 28, 2015 - Oysters not only transmit human norovirus; they also serve as a major reservoir for these pathogens, according to research published August 28 in Applied and Environmental Microbiology, a journal of the American Society for Microbiology. "More than 80 percent of... Read More

Mobile phone records may predict epidemics of mosquito-borne dengue virus

Boston, MA -- A new study led by researchers at Harvard T.H. Chan School of Public Health finds that mobile phone records can be used to predict the geographical spread and timing of dengue epidemics. More people around the world are becoming vulnerable to this deadly virus as climate change exp... Read More

BacterioFiles 214 - Cable-Chlorophyte Coop Conducts Current

This episode: Cable bacteria and algae set up electric grid in sediments!

(6 MB, 6.5 minutes)

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As a trio, three antibiotics that aren’t individually effective against a drug-resistant staph infection killed the deadly pathogen in test tubes and mice. Read More

TWiV 320: Retroviruses and cranberries

Vincent speaks with John Coffin about his career studying retroviruses, including working with Howard Temin, endogenous retroviruses, XMRV, chronic fatigue syndrome and prostate cancer, HIV/AIDS, and his interest in growing cranberries.

Host:  Read More

ASM Live at #ICAAC / ICC - Silicone Vaginal Rings Deliver Antiviral Drugs, Protect Women against HIV

Meriam Memmi, PhD candidate at University Jean Monnet of Saint-Etienne, France discusses her research which led the creation of a new birth control device with additional protective properties against sexually transmitted infections (STIs). STIs of viral origin constitute a major public health c... Read More
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