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MWV Episode 94 - TWiM #99: Careers in Biodefense
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A WORD on the constraints of influenza virus evolution

Evolution proceeds by selection of mutants that arise by error-prone duplication of nucleic acid genomes. It is believed that mutations that are selected in a gene are dependent on those that have preceded them, an effect known as epistasis. Analysis of a sequence of changes in the influenza vir... Read More

TWiV 303: Borna this way

The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome.


Hosts: Vincent Racaniello Read More

Smut, but the Safe For Work Kind, unless you work with plants....

So I told ccondayan I would post something lewd to MicrobeWorld (who probably thought I was joking). And what could be more lewd than genuine smut? Of course, since this is MicrobeWorld, I'm posting about the group of fungal plant pathogens referred to as smut. When I worked in a plant pathol... Read More

TWiP 79 letters


Jesse writes:


Doctors TWiP,


I came across this paper and thought it sounded interesting for a discussion on TWiP:


Colonisation resistance in the sand fly gut: Leishmania protects Lutzomyia longipalpis from bacterial infection
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Ebola Virus: A Grim, African Reality

There’s nothing like an outbreak of Ebola virus disease to bring a small, struggling African nation to international notice. One week we couldn’t place it on a map; the next week, after Ebola virus disease strikes, we know the body count and the name of the capital and whether its airport has cl... Read More

When Will We Have a Vaccine for Ebola Virus?

The latest outbreak of Ebola virus in west Africa is the worst ever—as of Monday, it had infected more than 1,200 people and claimed at least 672 victims since this spring. Guinea, Liberia and Sierra Leone all have confirmed cases. An official at Doctors Without Borders has declared the outbreak... Read More

Avoid Getting Sick: Top 8 Germiest Public Places Exposed

Worried about you or your kids picking up the flu virus or other common illnesses at school, in restrooms or at the mall? There’s good reason: Viruses and bacteria run rampant on the surfaces you touch every day. We blow the lid on the 8 germiest public places and give you expert tips to avoid g... Read More

Gut Microbes and Jet Lag, Shift-Work Weight Gain

Disruptions in the human circadian clock can throw off microbes in the gut, potentially boosting the risk of obesity, a new study suggests.

The results may help explain why shift workers and people who get jet lag by traveling frequently often pack on extra pounds.

"These surprising findin... Read More

Stanford bioengineer develops a 50-cent paper microscope

The Foldscope is a fully functional microscope that can be laser- or die-cut out of paper for around 50 cents.

This bookmark-sized microscope can be assembled in minutes, includes no mechanical moving parts, packs in a flat configuration, is extremely rugged and can be incinerated after to s... Read More

TWiV 300: So happy together

Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent  speaks with Dickson, Alan, Rich, and Kathy about their careers in science.


Hosts:  Read More

The Ebola Outbreak of 2014 2015 A Perfect Storm by Anthony Fauci

Presentation by Anthony S. Fauci, MD, Director, NIAID/NIH, Bethesda, MD, at the ASM Biodefense 2015 Meeting in Washington, D.C. on Feb 11, 2015. Read More

Bacteria Can't Cling to 'Repulsive' New Surface

Bacteria can’t stick to a new type of nanoscale surface that could prove useful in food processing, medical, and shipping industries.

The technology uses an electrochemical process called anodization to create nanoscale pores that change the electrical charge and surface energy of a metal sur... Read More

New Springtime Flu Strain Going Around New York

Thought you only had to deal with allergies these days? Well, maybe you've noticed some friends or work colleagues calling in sick lately—that may be because there's another flu strain making the rounds.

According to the Centers for Disease Control, influenza B is accounting for 55% of all vi... Read More

Microbe/Mineral Affinities

This is a paper from the Geomicrobiology lab at the Jackson School of Geosciences at the University of Texas at Austin. It was recently published in a special issue of Geomicrobiology Journal focused on geomicrobiology of subsurface microorganisms in cave environments.

In this study we attemp... Read More

Scientist Finds Link between Antibiotics and Bacterial Biofilm Formation Cause of Chronic Ear, Sinus, and Lung Infections

Researchers from the University of Southern California and the Oak Crest Institute of Science have discovered the link between antibiotics and bacterial biofilm formation leading to chronic lung, sinus and ear infections. The study results, published in the current issue of PLOS ONE, illustrate ... Read More

How E. coli passes safely through stomach acid

In some parts of the world, many small children become infected with severe diarrhea which often proves fatal. The condition is usually caused by strains of Escherichia coli (commonly known as E. coli) bacteria, and bacteria of the genus Yersinia. These bacteria attach themselves to the wall of ... Read More

New research shows that bacteria survive longer in contact lens cleaning solution than previously thought

Each year in the UK, bacterial infections cause around 6,000 cases of a severe eye condition known as microbial keratitis - an inflammation and ulceration of the cornea that can lead to loss of vision. The use of contact lenses has been identified as a particular risk factor for microbial kerati... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!


(15.9 MB, 17.4 minutes)


Show notes: 
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Early Exposure To Bacteria Protects Children From Asthma And Allergies

Babies who are exposed to both bacteria and allergens in the first year of life are less likely to develop asthma and allergies, a study finds.

It's the latest wrinkle in the hygiene hypothesis — the notion that exposure to bacteria trains the infant immune system to attack bad bugs and ignor... Read More

Scientists Build a Yeast Chromosome From Scratch. Next Up? Designer Genomes

Creating synthetic organisms with specially-tailored genomes is a long way off, but the first synthetic eukaryotic chromosome is a big step forward.

Humans have been using what they know about the biological world to make stuff for centuries—from beer to antibiotics. But, what if you could ma... Read More
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