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Continuing Discussion on Gain of Function

Should scientific journals publish gain-of-function (GOF) studies, especially those involving pathogens with pandemic potential? While journal editors at the American Society for Microbiology have done so after careful consideration, some scientists expressed concern over that decision. A series... Read More

TWiP 75 letters


David writes (re lice and iron):


All I remember that I know is that one time I let my cat endure a heavy flea infestation for an unconscionably long time. I redeemed myself, if at all, by the knowledge that I slept with her a lot, and so endured a share myself (b... Read More

1 in 25 patients gets infection in hospital

When antibiotics first started being used in the 1940's they were considered a "miracle drug". It seemed that bacterial infections would no longer be a problem for the world. However, recently, one gene is making it seem as though the end of antibiotics is at hand. This gene is New Delhi metallo... Read More

Breastfeeding increases prevalence of Lactobacilli and Bifidobacteria in infants

Breastfeeding until at least nine months of age increases prevalence in the gastrointestinal tract of Lactobacilli and Bifidobacteria, species which are known to contribute to development of a healthy immune system, according to a paper describing the establishment of the intestinal microbiota d... Read More

TWiV 289: Vinny and the capsids

Vinny and the capsids answer listener questions about the definition of life, state vaccination laws, the basic science funding problem, viral ecology, inactivation of viruses by pressure, and much more.


Hosts:  Read More

What’s eating you? The first food web inside humans suggests potential new treatments for infection

Imagine going to the doctor with an infection and being sent home with a course of drugs. Unknown to your doctor you actually have two infections. If you take the drugs will the other infection go away by itself? What if you take the drugs and the other infection gets worse? This quandary faces ... Read More

The Strange Connection Between Germs and Sherlock Holmes

Sherlock Holmes was as much a scientist as a detective. Maybe that’s because his creator, Arthur Conan Doyle, was influenced by a detective of science: Robert Koch, a German doctor who helped prove the existence of germs. In his new book, The Remedy, Thomas Goetz traces connections between the t... Read More

TWiM 77 Letters


Francois writes:


Hello Twim team,


After reading the Pasteur lecture.
It seems that the idea of using the Pseudomonas aer, "coal & septicemia" came from a demonstration that the "bactericidie" in the blood from animal with anthrax ("sang charbonne... Read More

Frozen bacteria repair their DNA at -15ºC

Bacteria encased in ice can be resuscitated after thousands, perhaps even millions of years. How these hardy bugs manage to survive deep freeze is something of a mystery. If nothing else, the low levels of radiation hitting Earth’s surface should cause any ice-bound bacterium’s DNA to break apa... Read More

TWiV 316: The enemy of my enemy is not my friend

Vincent, Alan, Rich and Kathy discuss how interleukin 10 modulation of Th17 helper cells contributes to alphavirus pathogenesis.


Hosts: Vincent Racaniello Read More

Diet Affects Men’s and Women’s Gut Microbes Differently

The microbes living in the guts of males and females react differently to diet, even when the diets are identical, according to a study by scientists from The University of Texas at Austin and six other institutions published this week in the journal Nature Communications. These results suggest ... Read More

Ocean microbes display remarkable genetic diversity in each drop of seawater

The smallest, most abundant marine microbe, Prochlorococcus, is a photosynthetic bacteria species essential to the marine ecosystem. An estimated billion billion billion of the single-cell creatures live in the oceans, forming the base of the marine food chain and occupying a range of ecological... Read More

Human Sweat's Filthy Attributes Stop Bacteria-Fighting Brass

Human sweat is actually much dirtier and bacteria-filled than we initially thought. Scientists have found that sweaty hands can reduce the effect that brass objects have of fighting bacteria. Brass objects can be found in hospitals and schools and sweat can fight off its abilities just an hour a... Read More

BacterioFiles 183 - Simplex-Sick Stem Cell Salve

This episode: Cancer-killing viruses could work even better when loaded into stem cells!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

Ebola 101: The Facts Behind A Frightening Virus

Health workers have called the Ebola outbreak in West Africa unprecedented, overwhelming and even out of control.

With 844 cases so far, it's the largest and deadliest outbreak since the virus was discovered in 1976. And it doesn't show signs of slowing down. On Tuesday, the World Health Orga... Read More

The truth behind the '5-Second Rule': When in doubt, throw it out

The burger patty that slides off the plate, the ice cream treat that plops on the picnic table, the hot dog that rolls off the grill – conventional wisdom has it that you have five seconds to pick it up before it is contaminated.

Fact or folklore?

“A dropped item is immediately contaminate... Read More

TWiV 290: Baylor goes viral

Vincent meets up with Janet Butel and Rick Lloyd at Baylor College of Medicine to talk about their work on polyomaviruses and virus induced stress.


 


Host: Vincent Racaniello


Guests... Read More

TWiV 283: No Reston for the weary

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 Hosts: Vincent RacanielloAlan Dove Read More

TWiV 288: ebircsnart esreveR

The Twivsters discuss how reverse transcriptase encoded in the human genome might produce DNA copies of RNA viruses in infected cells.


Hosts: Vincent Racaniello Read More

Healthy Lung Microbes Keep Mice Breathing Easy

Like humans, mice start life with sterile lungs that soon get colonized by microbes, which appear to protect the lung tissue from an asthma-like reaction in the presence of dust mites.

Human cells are outnumbered ten-to-one by the microbes that thrive in and on us. Now a study finds that the ... Read More
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