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Ebola Outbreak 2014 2015 by Dr. Fauci

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How E. coli passes safely through stomach acid

In some parts of the world, many small children become infected with severe diarrhea which often proves fatal. The condition is usually caused by strains of Escherichia coli (commonly known as E. coli) bacteria, and bacteria of the genus Yersinia. These bacteria attach themselves to the wall of ... Read More

Cyanobacterium found in algae collection holds promise for biotech applications

Cyanobacteria could serve as a synthetic biology chassis that could be retooled for the production of biofuels, drugs or chemcials. So far, however, they have been held back by sluggish growth that makes it difficult to conduct the initial experiments needed to characterize their genetic and met... Read More

Gut Microbes and Jet Lag, Shift-Work Weight Gain

Disruptions in the human circadian clock can throw off microbes in the gut, potentially boosting the risk of obesity, a new study suggests.

The results may help explain why shift workers and people who get jet lag by traveling frequently often pack on extra pounds.

"These surprising findin... Read More

Bacteria Can't Cling to 'Repulsive' New Surface

Bacteria can’t stick to a new type of nanoscale surface that could prove useful in food processing, medical, and shipping industries.

The technology uses an electrochemical process called anodization to create nanoscale pores that change the electrical charge and surface energy of a metal sur... Read More

ICAAC 2014 - New Antimicrobial Strategy Silences NDM-1 Resistance Gene in Pathogens

Researchers have created a synthetic DNA analog that can bind to and silence the gene responsible for NDM-1, a severe form of antibiotic resistance that can make ... Read More

When Will We Have a Vaccine for Ebola Virus?

The latest outbreak of Ebola virus in west Africa is the worst ever—as of Monday, it had infected more than 1,200 people and claimed at least 672 victims since this spring. Guinea, Liberia and Sierra Leone all have confirmed cases. An official at Doctors Without Borders has declared the outbreak... Read More

Scientist Finds Link between Antibiotics and Bacterial Biofilm Formation Cause of Chronic Ear, Sinus, and Lung Infections

Researchers from the University of Southern California and the Oak Crest Institute of Science have discovered the link between antibiotics and bacterial biofilm formation leading to chronic lung, sinus and ear infections. The study results, published in the current issue of PLOS ONE, illustrate ... Read More

We Are Our Bacteria

Like ecosystems the world over, the human microbiome is losing its diversity, to the potential detriment of the health of those it inhabits.

Dr. Martin J. Blaser, a specialist in infectious diseases at the New York University School of Medicine and the director of the Human Microbiome Program... Read More

Scientists Build a Yeast Chromosome From Scratch. Next Up? Designer Genomes

Creating synthetic organisms with specially-tailored genomes is a long way off, but the first synthetic eukaryotic chromosome is a big step forward.

Humans have been using what they know about the biological world to make stuff for centuries—from beer to antibiotics. But, what if you could ma... Read More

Apes Have Better Gut Bugs than Humans

It's not a secret that the microbes living in our guts play a huge role in our well-being, or that, at least in the United States, we're doing a good job of killing them off.

But now new research finds that apes -- our closest relative -- have much more varied gut flora than humans do, and es... Read More

TWiV 323: A skid loader full of viromes

Hosts: Vincent RacanielloDickson DespommierAlan Dove, Read More

Highly Drug Resistant, Virulent, Strain of Pseudomonas Aeruginosa Arises in Ohio (press release)

A team of clinician researchers has discovered a highly virulent, multidrug resistant form of the pathogen, Pseudomonas aeruginosa, in patient samples in Ohio. Their investigation suggests that the particular genetic element involved, which is still rare in the United States, has been spreading ... Read More

HOW MAPLE SYRUP COULD IMPROVE ANTIBIOTICS

A concentrated extract of maple syrup makes disease-causing bacteria more susceptible to antibiotics, according to laboratory experiments.

The findings, which will appear in the journal Applied and Environmental Microbiology, suggest that combining maple syrup extract with common antibiotics ... Read More

Early Exposure To Bacteria Protects Children From Asthma And Allergies

Babies who are exposed to both bacteria and allergens in the first year of life are less likely to develop asthma and allergies, a study finds.

It's the latest wrinkle in the hygiene hypothesis — the notion that exposure to bacteria trains the infant immune system to attack bad bugs and ignor... Read More

ICAAC 2014 - Antibiotic Stewardship: Saving Drugs, Saving Money

Antibiotic stewardship programs, which promote the appropriate use of antibiotics in hospitals and other healthcare centers, can not only lead to reduction in antibiotic use with no adverse effects but can also lead to significant savings, over $600,000 annually in the case of one New York Ho... Read More

TWiP 82 letters


Allan writes:


Dear Vincent, Dickson and Daniel,


I like your idea of a TWIP coffee mug prize (or maybe a mug discount).


In this second case study you presented, the present symptoms are pretty vague, but his history is interesting. Also since with ... Read More

Protein ID'd as possible universal therapeutic target for many infections, including Ebola

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as MRSE and MRSA, according to a Virginia Commonwealth University-led pre-clinical study published this month in the Journal of Cel... Read More

TWiV 318: Last year in virology

The TWiV gang reviews ten fascinating, compelling, and riveting virology stories from 2014.


Hosts: Vincent RacanielloDickson Despommier, ... Read More

Parvo Trial Shows Promising Results In Effort To Combat Puppy Virus

A North Dakota company that discovered an antibody technology while trying to cure flocks of dying geese is using its research for a more warm and fuzzy purpose: saving puppies.

Early tests performed on about 50 puppies in seven U.S. states for Grand Forks-based Avianax have resulted in a 90 ... Read More
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