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How brain guards itself against virus attacks

Infections in the central nervous system are rare thanks to our brain's unique defence system that prevents viruses from invading, finds a study. The research explains a long-standing mystery.

Click 'source' to read more. Read More

New 'gut bacteria' clinical study could help reduce side-effects of radiotherapy

Researchers will examine the role of gut bacteria in influencing the side-effects patients experience after radiotherapy, in the first clinical study of its type.

The study will be carried out by researchers at The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Tru... Read More

Molecule discovered that smuggles toxins from intestinal pathogens into human cells

Prof. Dr. Dr. Klaus Aktories and Dr. Panagiotis Papatheodorou from the Institute of Experimental and Clinical Pharmacology and Toxicology of the University of Freiburg have discovered the receptor responsible for smuggling the toxin of the bacterium Clostridium perfringens into the cell. The Tpe... Read More

Gut Bacteria Lose their Tails to Evade Antibodies

New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.

In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More

How bacteria with a sweet tooth may keep us healthy

Some gut bacterial strains are specifically adapted to use sugars in our gut lining to aid colonisation, potentially giving them a major influence over our gut health.

We live in a symbiotic relationship with trillions of bacteria in our gut. They help us digest food, prime our immune system ... Read More

Progress in understanding immune response in severe schistosomiasis

A mechanism that may help explain the severe forms of schistosomiasis, or snail fever, has been discovered by researchers. Schistosomiasis is one of the most prevalent parasitic diseases in the world. The study in mice may also offer targets for intervention and amelioration of the disease. Alth... Read More

The Way You’re Born Can Mess With the Microbes You Need to Survive

Throughout the animal kingdom, mothers transfer microbes to their young while giving birth. Different species of tadpoles acquire specific skin bacteria from mother frogs even though they all live in the same pond with the same bacterial background. Emerging chicken eggs get inoculated with micr... Read More

Rotavirus Activates Lymphocytes from Non-Obese Diabetic Mice by Triggering Toll-Like Receptor 7 Signaling and Interferon Production in Plasmacytoid Dendritic Cells

It has been proposed that rotavirus infection promotes the progression of genetically-predisposed children to type 1 diabetes, a chronic autoimmune disease marked by infiltration of activated lymphocytes into pancreatic islets. Non-obese diabetic (NOD) mice provide a model for the human disease.... Read More

Rare 'polio-like' disease reports

US doctors are warning of an emerging polio-like disease in California where up to 20 people have been infected.

A meeting of the American Academy of Neurology heard that some patients had developed paralysis in all four limbs, which had not improved with treatment.

The US is polio-free, b... Read More

Cilia use different motors for different tasks

Cilia — short, hair-like fibers — are widely present in nature. Single-celled paramecia use one set of cilia for locomotion and another set to sweep nutrients into their oral grooves. Researchers at Brown have discovered that those two cilia sets operate at different speeds when the viscosity of... Read More

A microbe's fountain of youth

The yeast S.pombe is one of the best-studied microbes in the world. First isolated from East African millet beer over a century ago, it's been used as a model organism in molecular and cell biology for the past sixty years. And yet scientists have now just uncovered what may be its most striking... Read More

Teaching Freshmen about Transformation, Drug Resistance, and Gene Regulation!

In this blog post, I describe how I use the commonly available pGLO plasmid to teach freshman students basic concepts about transformation, receptor recognition, drug resistance mechanisms, and gene regulation. Oh, and fluorescence via GFP! Read More

Scientists explore the mechanisms of viruses' shells

The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the genome into the infected cell. The scientists of the International School for Advanced Stu... Read More

Architecture May Influence Which Microbes Surround You

They have us surrounded. Even inside the spaces we build for ourselves — like homes and offices — we are a tiny minority. Invisible bacteria, fungi, and viruses outnumber us by orders of magnitude. We will always be outnumbered, but we may have a say in which microbes we’re surrounded by, accord... Read More

The malaria pathogen’s cellular skeleton under a super-microscope

The tropical disease malaria is caused by the Plasmodium parasite. For its survival and propagation, Plasmodium requires a protein called actin. Scientists of the Helmholtz Centre for Infection Research (HZI) in Germany used high-resolution structural biology methods to investigate the different... Read More

Staph Germs Hide Out In The Hidden Recesses Of Your Nose

Otherwise innocuous bacteria can cause deadly infections when people have surgery or fall ill. To prevent trouble, patients sometimes have their bodies scrubbed clean of Staphylococcus aureus. But it doesn't always work.

That may because the germs thrive in upper recesses of the nose, far fro... Read More

Diversity of Antiviral Bacteria Discovered

Wolbachia, a symbiont that resides naturally up to 70% of all insect species, are probably the most prevalent infectious bacteria on Earth. In 2008 Luis Teixeira, now a principal investigator at the Instituto Gulbenkian de Ciência, and other scientists have discovered that Wolbachia can protect ... Read More

Fungal pathogen shows profound effects from spaceflight

At Arizona State University’s Biodesign Institute, Cheryl Nickerson and her team have been investigating the intriguing effects of spaceflight on microbial pathogens.

In a new paper appearing in the current issue of the journal PLOS ONE, the team reports their recent work examining spacefligh... Read More

Antibiotic resistance mechanisms of clinically important bacteria.

Antibiotic resistance mechanisms of clinically important bacteria. Read More

Virology question of the week: why a segmented viral genome?

This week’s virology question comes from Eric, who writes:

I’m working on an MPH and in one of my classes we are currently studying the influenza virus. I’d forgotten that the genome is in 8 separate parts. Curious, I’ve been searching but can’t find any information as to why that is?

What... Read More

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