The genome of viruses is usually enclosed inside a shell called capsid. Capsids have unique mechanic properties: they have to be resistant and at the same time capable of dissolving in order to release the genome into the infected cell. The scientists of the International School for Advanced Stu... Read More
The yeast S.pombe is one of the best-studied microbes in the world. First isolated from East African millet beer over a century ago, it's been used as a model organism in molecular and cell biology for the past sixty years. And yet scientists have now just uncovered what may be its most striking... Read More
Antibiotic resistance poses a dire threat in hospitals and communities. To help limit such risk, health care professionals should begin sequencing the DNA of offending bacteria, the White House’s council of science advisors said in a new report. Armed with genome-sequencing technology that enabl... Read More
Some gut bacterial strains are specifically adapted to use sugars in our gut lining to aid colonisation, potentially giving them a major influence over our gut health.
We live in a symbiotic relationship with trillions of bacteria in our gut. They help us digest food, prime our immune system ... Read More
In a surprising new finding, researchers have discovered that bacterial movement is impeded in flowing water, enhancing the likelihood that the microbes will attach to surfaces. The new work could have implications for the study of marine ecosystems, and for our understanding of how infections t... Read More
Researchers have discovered that a type of white blood cell carries a deadly fungus into the brains of HIV positive patients, causing meningitis which kills more than 600,000 people a year. The discovery could lead to more effective ways of tackling the deadly fungus as it infects the human body... Read More
Fighting malaria in today’s world will require a new, targeted approach, and Virginia Tech researchers are out for blood.
The parasites responsible for the mosquito-borne infectious disease are increasingly resistant to current drug approaches, and almost half of the world is at risk of cont... Read More
A Connecticut law requiring flu shots for children entering preschool or daycare has reduced flu-related hospitalizations of young children by 12 percent, according to a new study. The jump in flu vaccinations of young children -- to 84 percent in 2012-2013 from about 68 percent in 2009-2010 -- ... Read More
Researchers at the University of Virginia School of Medicine studying a potentially deadly parasitic infection have discovered a previously unknown way that human cells are killed, with the parasitic amoeba essentially nibbling cells to death – as a piranha might attack its prey.
Until now, r... Read More
If food products are not produced in a hygienic environment, consumers can face the threat of dangerous pathogens. This is exactly what happened in 2009 and 2010 when two different strains of Listeria monocytogenes were found in the traditional Austrian curd cheese known as “Quargel”. 34 people ... Read More
Infectious disease specialists at the Johns Hopkins Children’s Center have identified a protein that regulates the body’s immune response to cytomegalovirus (CMV), a common pathogen that causes lifelong infections and can lead to devastating illness in newborns and those with weakened immune sys... Read More
The traditional light microscope is bulky and expensive. Dr Tri Phan and Dr Steve Lee from the Garvan Institute of Medical Research and Australian National University used gravity to manufacture high-performance polymer lenses. These can be seamlessly integrated with 3D printing and mini-LEDs to... Read More
While I was working on the “H1N-What?” post, I also knew there would soon be questions about MERS (Middle East Respiratory Syndrome), just as there were about SARS. So here are the essentials of what we know and don’t know about MERS—which has just been reported in the U.S.—as well as intriguing... Read More
Yale University researchers have determined how a scarce molecule produced by marine bacteria can kill cancer cells, paving the way for the development of new, low-dose chemotherapies.
The molecule, lomaiviticin A, was previously shown to be lethal to cultured human cancer cells, but the mech... Read More
Sixty years ago Jacob, Brenner and Cuzin devised their 'Replicon Model', inspiring and useful guideline for replication research ever since. According to the model, a 'Replicon' is a genetic element replicated from a single 'Replicator'—replication origin, in modern terms—and replication is trig... Read More
Yeast aren’t the only microbes that help turn boring grapes into the delicious, seductive, complex, confusing, subtle, and totally splendiferous tonic known as wine. In addition to those well-known fermenters, a type of bacteria called Oenococcus oeni (for reasons that will be obvious to oenophi... Read More
A common plant puts out a welcome mat to bacteria seeking to invade, and scientists have discovered the mat's molecular mix. The study published this week in the Proceedings of the National Academy of Sciences reveals new targets during the battle between microbe and host that researchers can ex... Read More
About 6,000 years ago, a bacterium underwent a few genetic changes. These allowed it to expand its habitat from the guts of mice to that of fleas. Such changes happen all the time, but in this particular instance the transformation eventually resulted in the Black Death that wiped out a third of... Read More
An international team of scientists has identified the precise biochemical key that wakes up the body’s immune cells and sends them into action against invading bacteria and fungi.
The patented work, published in Nature today, provides the starting point to understanding our first line of defen... Read More
We need to understand how diverse communities of microbes interact, but doing so in the gut is hard. Why not turn to a model system, where diverse microbial communities interact, but in an environment that’s easier to study? We have a long history of using model systems in biology – the mice I m... Read More