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Mining Marine Microbes for New Drugs

This slideshow outlines the work of WHOI scientists Tracy Mincer and Kristen Whalen in the quest to beat antibiotic resistance through bioprospecting in the ocean. Read More

Humans differ in their personal microbial cloud

Dispersal of microbes between humans and the built environment can occur through direct contact with surfaces or through airborne release; the latter mechanism remains poorly understood. Humans emit upwards of 106 biological particles per hour, and have long been known to transmit path... Read More

BacterioFiles 227 - Microbe Menaces Meningitis

This episode: Colonizing ourselves with friendly bacteria could drive out more risky ones, such as those that cause meningitis!

(9.8 MB, 10.6 minutes)

Show notes: 
Read More

Prostate Cancer Are Classified Into Five Different Types

Prostate Cancer Are Classified Into Five Different Types
BOC Sciences-Following with the classification of breast cancer, recently prostate cancer is also categorized by its symptoms, which will promote custom treatment and help people who suffer chronically from prostate cancer avoid adverse e... Read More

The bacteria-fighting super element that’s making a comeback in hospitals: copper

Ancient Egyptians used copper to sterilize chest wounds and drinking water. Greeks, Romans and Aztecs relied on copper compounds to treat burns, headaches and ear infections. Thousands of years later, the ancient therapeutic is being embraced by some hospitals because of its ability to kill bact... Read More

Northwestern receives $17.5 million grant for HIV prevention research

Northwestern Medicine scientists have received a five-year, $17.5 million grant from the National Institutes of Health (NIH) for an interdisciplinary project that aims to invent, develop and test an implantable drug delivery system to protect high-risk individuals from HIV infection for up to a ... Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!

(10 MB, 10.8 minutes)

Show notes: 
News item/ Read More


Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More

Drug Resistant Microbes were Found in African Wildlife

BOC Sciences-Drug resistance has always been one of the issues that scientists work hard to find ways out for better diseases treatment, as it hinders many drugs that were developed with much effort from taking effect in the body. And till now, there is little known about the formation of antibi... Read More

TWiM 111 Letters

Noah writes:

Dear Dr. Schaechter,

First off, I want to thank you for the effort you and your colleagues have invested in Small Things Considered and the podcast TWIM.  Back when I had a longer commute to work, I listened more religiously than now, wh... Read More

Viruses thrive in big families, in sickness and in health

SALT LAKE CITY - The BIG LoVE (Utah Better Identification of Germs-Longitudinal Viral Epidemiology) study, led by scientists at the University of Utah School of Medicine, finds that each bundle of joy puts the entire household at increased risk for infection with viruses that cause colds, flu, a... Read More

Host genetics played a role in vaccine efficacy in the RV144 HIV vaccine trial

July 15, 2012 (SILVER SPRING, Md.) - New findings published today in the journal Science Translational Medicine show that host genetics played a role in protection against HIV infection in the landmark RV144 vaccine trial conducted in Thailand. Read More

Simple intervention can moderate anti-vaccination beliefs, study finds

CHAMPAIGN, Ill. -- It might not be possible to convince someone who believes that vaccines cause autism that they don't. Telling skeptics that their belief is not scientifically supported often backfires - strengthening, rather than weakening, their anti-vaccine views. But researchers say they h... Read More

Peptides Produced by Gut Bacteria Could Hinder the Development of Type 1 Diabetes

BOC Sciences-Studies have found that peptides produced by a certain type of gut bacteria can be used to prevent type 1 diabetes from deteriorating and the lack of such gut bacteria along with the peptides may be the reason for type 1 diabetes in newborn babies.

The study was conducted by a co... Read More

BacterioFiles 190 - Bacteriophages Bust Biofilm Beacons

This episode: Engineered phages can both kill bacteria and disrupt their communications!

(14.8 MB, 16.2 minutes)

Show notes: 
Journal Paper

Read More

Burden of dengue, chikungunya in India far worse than understood

New Johns Hopkins Bloomberg School of Public Health research finds new evidence that an extremely high number of people in southern India are exposed to two mosquito-borne viruses -- dengue and chikungunya. Read More

Periodontitis and Heart Disease: Researchers Connect the Molecular Dots

Washington, DC – September 11, 2015 - Periodontitis is a risk factor for heart disease. Now a team of researchers has shown that a periodontal pathogen causes changes in gene expression that boost inflammation and atherosclerosis in aortic smooth muscle cells. The research is published ahead of ... Read More

New resource makes gene-editing technology even more user friendly

Researchers at Harvard University and the University of California, San Diego, have developed a new user-friendly resource to accompany the powerful gene editing tool called CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential t... Read More

Wasps do a gain-of-function experiment in caterpillars

Parasitic wasps inject their eggs into lepidopteran hosts, where they carry out their developmental stages. Along with the eggs, the wasps also deliver viruses carrying genes encoding proteins which inhibit caterpillar immune defenses. Some of these genes are permanently transferred to the lepid... Read More

Developing a better flu vaccine

Johns Hopkins Bloomberg School of Public Health researchers say they have developed a method that could make a nasal spray flu vaccine effective for those under two and over 49 - two groups for which the vaccine is not approved. Read More
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