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TWiV 425: All picornaviruses, all the time

The TWiVaniellos discuss a thermostable poliovirus empty capsid vaccine, and two cell genes that act as a switch between entry and clearance of picornavirus infection.


Hosts: Vincent Racaniel... Read More

THE RIDDLE OF THE R.I.D.L _ Zika virus Comics (Playlist)

In Zanzare, the new comic from Cimaza (www.cimazacomics.com/), we are plunged head-first into the global mystery of the Zika virus. We meet the mosquitoes (in Italian: zanzare) implicated in its spread; but the insects plead their innocence, saying it's all a misunderstanding. They lay their cas... Read More

TWiV 406: Pow, right in the enteroids!

The TWiV team discusses eye infections caused by Zika virus, failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids.


Hosts:  Read More

CMV Is a Greater Threat to Infants Than Zika, but Far Less Often Discussed

The world has been galvanized by the Zika epidemic spreading through the Americas, which has left more than two thousand infants with severe brain damage. But for pregnant women and their infants in the United States, cytomegalovirus, or CMV, is the far greater viral threat.

Every year, 20,00... Read More

MMP #17: How bacteria can change graphene to propel rotors.

Host: Jeff Fox with special guests, Julia Yeomans and Vikas Berry.


Julia Yeomans of Oxford University in the United Kingdom and chemical engineer
Vikas Berry of the University of Illinois, Chicago, talk with Jeff Fox about their separate, but in some ways similar, research effor... Read More

TWiV 421: Like flies on shot

The TWiVnauts present another example of an infectious but replication incompetent vaccine, an insect specific arborvirus bearing chikungunya virus structural proteins.


Hosts: Vincent Racaniello,&n... Read More

BacterioFiles Special - Novozymes' Nathan Cude

This episode: An interview with Dr. Nathan Cude, team leader at Novozymes BioAg Alliance, working on finding and bringing to market soil microbes that can help crops grow!


(14.1 MB, 15.4 minutes)


Show notes: 
Read More

A role for siderophores in Klebsiella pneumoniae pathogenesis

Despite increasing awareness of Klebsiella pneumoniae as a public health risk, there has been relatively little understood about its mechanisms of pathogenesis.

The bacterium, estimated to be the third most common cause of hospital-acquired infections in the United States in a recent study, c... Read More

TWiV 422: Watching the icosahedron drop

The TWiVestigators wrap up 2016 with a discussion of the year's ten compelling virology stories.


Hosts: Vincent Racaniello Read More

Dispatches from ASM Microbe - Sunday

We’ve had a whirlwind of amazing talks, poster sessions, and networking sessions so far at ASM Microbe 2016. In our previous two Dispatches from ASM Microbe, we’ve covered microbiomes, for which research ranges from extremely basic (Which microbes are present? How do we quantify them?) to clinic... Read More

BacterioFiles 273 - Bottle-Biting Bacteria

This episode: Newly discovered bacteria can break down especially long-lived type of plastic!


(6.4 MB, 7 minutes)


Show notes: 




Read More

Diverse fungi inhabit chronic wounds and inhibit healing

Gruesome, ghastly, grisly. These are the words that popped into my head when I googled images of diabetic foot ulcers—one of the most common chronic wounds creating a silent and costly epidemic in healthcare.

Perhaps even more shocking is the mortality rate connected to these open wounds, wh... Read More

BacterioFiles 287 - Producing Potent Pathogen Prophylaxes

This episode: Polymer-coated bacteria make really good vaccines!


(9.2 MB, 10 minutes)


Show notes: 


News item



Jou... Read More

BacterioFiles 286 - Prokaryote Prevents Pregnancy Pathogen

This episode: Bacteria in mosquito cells can block transmission of Zika virus!


(8.1 MB, 8.9 minutes)


Show notes: 


News item
Read More

TWiM #145: Anything but Academic

Vincent meets up with Catharine Bosio, Michael Merchlinsky, and Shilpa Gadwal at the ASM Biothreats meeting to talk about careers for scientists outside of the ivory tower.


Host: Vincent Racaniello


... Read More

TWiV 432: Conjunction junction, what's your function?

The TWiVites discuss Zika virus seroprevalence in wild monkeys, Zika virus mRNA vaccines, and a gamete fusion protein inherited from viruses.


Hosts: Vincent Racaniello Read More

TWiM 142 Letters

Carole writes:


Dear Vincent and hosts of TWIM,


I am a long time listener and fan of your weekly TWIM podcasts. I really enjoyed the latest episode in which you discussed a paper by Kelly Wrighton and colleagues, and was especially... Read More

BacterioFiles 274 - Proteobacteria Purify Piscine Pee

This episode: Bacteria in the gills of fish help break down their metabolic wastes before they reach toxic levels!


(7.4 MB, 8.1 minutes)


Show notes: 


Read More

BacterioFiles 288 - Caulobacter's Copper Coping Capabilities

This episode: Some bacterial species use multiple strategies within a single population to deal with environmental challenges!


(8.9 MB, 9.7 minutes)


Show notes: 


Journal Paper:

Lawarée E, Gillet S, Louis G, Tilqui... Read More

TWiV 419: The selfless gene

The TWiVrific gang reveal how integration of a virophage into the nuclear genome of a marine protozoan enhances host survival after infection with a giant virus.


Hosts: Vincent Racaniello Read More

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