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Early HIV treatment improves survival in some patients with newly diagnosed TB

PITTSBURGH, July 9, 2015 - Starting anti-HIV treatment within two weeks of the diagnosis of tuberculosis, or TB, improved survival among patients with both infections who had very low immune-cell counts, according to an analysis by researchers at the University of Pittsburgh Graduate School of H... Read More

Better Chocolate with Microbes

For decades, researchers have worked to improve cacao fermentation by controlling the microbes involved. Now, to their surprise, a team of Belgian researchers has discovered that the same species of yeast used in production of beer, bread, and wine works particularly well in chocolate fermentati... Read More

BacterioFiles 183 - Simplex-Sick Stem Cell Salve

This episode: Cancer-killing viruses could work even better when loaded into stem cells!


(8.3 MB, 9 minutes)


Show notes: 
News item/ Read More

TWiV 308: The Running Mad Professor

Tom talks with Vincent about viral central nervous system infections of global importance, Ebola virus, and running the fastest marathon dressed as a doctor.


Host: Vincent Racaniello Read More

TWiP 85: Channeling tryps

Vincent, Dickson, and Daniel explain how trypanolytic factor forms membrane channels to lyse trypanosomes, and present a new case study.


Hosts: Vincent Racaniello Read More

Virus-carrying mosquitoes are more widespread than ever, and spreading

Scientists behind the first global distribution maps of two species of dengue and chikungunya-carrying mosquitoes warn they are spreading to new areas where they could cause disease. Read More

BacterioFiles 201 - Plastic-Producing Prokaryote Process

This episode: Bacteria from wastewater treatment sludge can produce lots of biodegradable plastic!


(7.1 MB, 7.75 minutes)


Show notes: 
Jour... Read More

Towards an HIV vaccine

Neutralizing antibodies (Nabs) are immune proteins that recognize, bind to, and trigger the elimination of virus before it can establish a chronic infection. How to elicit a potent Nab response capable of protecting against different HIV subtypes and against different modes of infection is criti... Read More

TWiP 84: Bigfoot

Vincent, Dickson, and Daniel consider the delivery of anti-trypanosome nanobodies to the tsetse fly via a bacterial symbiont, and present a new case study.


Hosts: Vincent Racaniello Read More

TWiV 344: Glaswegians go viral

Host: Vincent Racaniello


Guests: Ruth Jarrett Read More

TWiM 107 Letters

Jim writes:


Hi Vince,
For your interest in listening to physics, there is a podcast called The Titanium Physicists Podcast. They use a conversational format similar to what you use. They have a panel of experts and a guest who is not a physicist but who is accom... Read More

TWiV 305: Rhymes with shinola

Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States.


Hosts:  Read More

Health-care providers a major contributor to problem of antibiotic overuse

SALT LAKE CITY - 10 percent of health care providers write an antibiotic prescription for nearly every patient (95 percent or more) who walks in with a cold, bronchitis or other acute respiratory infection (ARI), according to a new Centers for Disease Control and Prevention-supported study publi... Read More

B cell depletion benefits ME/CFS patients

Patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) showed clinical improvement after extended treatment with the anti-B-cell monoclonal antibody rituximab. This result suggests that in a subset of patients, ME/CFS might be an autoimmune disease. Read More

ICAAC 2014 - How Quickly Viruses Can Contaminate a Building

Using tracer viruses, researche... Read More

TWiP 92 letters

 


David writes:


Dear Vincent, Dickson and Daniel,

I am one of the co-authors (from the London School of Hygiene & Tropical Medicine) of the PloS Pathogens paper you highlighted on the malaria parasite as part of TWiP 91 on June 20th. Thank... Read More

TWiM #104: Feed me polyamines, biofilm

Hosts: Vincent RacanielloMichael Schmidt, ... Read More

THESE YEAST CELLS SAY ‘HI’ AND OTHERS RESPOND

Scientists have engineered yeast cells that can “talk” to one another using a versatile plant hormone called auxin.

Typically, these simple fungal cells (Saccharomyces cerevisiae) usually do their jobs—making bread rise or converting sugar into alcohol—without having to communicate or work to... Read More

BacterioFiles 222 - Cells Store Solar Sparks

This episode: Bacteria engineered to produce liquid fuel can eat carbon dioxide and hydrogen from solar-powered water-splitting!


(11.2 MB, 12.25 minutes)


Show notes: 
Read More

Host genetics played a role in vaccine efficacy in the RV144 HIV vaccine trial

July 15, 2012 (SILVER SPRING, Md.) - New findings published today in the journal Science Translational Medicine show that host genetics played a role in protection against HIV infection in the landmark RV144 vaccine trial conducted in Thailand. Read More
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