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TWiM 91 Letters



Jacob writes:
Hello hosts of TWiM and TWiV,
I'm sending this to both podcasts because I'm interested in hearing what all of you have to say (I figure that I'm going to catch Dickson on TWiV, but if not feel free to ask him on TWiP).


I saw this que... Read More

TWiP 77 letters

Andy writes:


Dear Professors,


I have been following TWIP for several years. I am a software engineer and parasitology is only an avocation. As an undergraduate in the early 80's I discovered my love of history of science and ecology, although I continued the p... Read More

Immune upgrade gives 'HIV shielding'

Doctors have used gene therapy to upgrade the immune system of 12 patients with HIV to help shield them from the virus's onslaught. It raises the prospect of patients no longer needing to take daily medication to control their infection. The patients' white blood cells were taken out of the body... Read More

TWiV 300: So happy together

Recording together for the first time, the TWiV team celebrates their 300th recording at the American Society for Microbiology headquarters in Washington, DC, where Vincent  speaks with Dickson, Alan, Rich, and Kathy about their careers in science.


Hosts:  Read More

Protein ID'd as possible universal therapeutic target for many infections, including Ebola

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as MRSE and MRSA, according to a Virginia Commonwealth University-led pre-clinical study published this month in the Journal of Cel... Read More

Commonly used pain relievers have added benefit of fighting bacterial infection

Some commonly used drugs that combat aches and pains, fever, and inflammation are also thought to have the ability to kill bacteria. New research reveals that these drugs, better known as nonsteroidal anti-inflammatory drugs, act on bacteria in a way that is fundamentally different from current ... Read More

TWiV 312: She sells B cells

The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria.


Hosts:  Read More

Artificial Spleen Cleans Ebola from Blood

Researchers have developed a high-tech method to rid the body of infections — even those caused by unknown pathogens. A device inspired by the spleen can quickly clean blood of everything from Escherichia coli to Ebola, researchers report on September 14 in Nature Medicine.

Blood infections c... Read More

Getting a Knit Bacteriophage From a Former Student!

A former student dropped by my lab this morning, and brought me a gift: a knit bacteriophage! Many times, as educators, we hear what we haven't done well, or could do better. Sometimes, like today, we get a priceless "thank you" from a former student. Read More

ICAAC 2014 - New Antimicrobial Strategy Silences NDM-1 Resistance Gene in Pathogens

Researchers have created a synthetic DNA analog that can bind to and silence the gene responsible for NDM-1, a severe form of antibiotic resistance that can make ... Read More

How E. coli passes safely through stomach acid

In some parts of the world, many small children become infected with severe diarrhea which often proves fatal. The condition is usually caused by strains of Escherichia coli (commonly known as E. coli) bacteria, and bacteria of the genus Yersinia. These bacteria attach themselves to the wall of ... Read More

Giant virus revived from deep freeze in Siberian tundra

A 30,000-year-old giant virus has been revived from the frozen Siberian tundra, sparking concern that increased mining and oil drilling in rapidly warming northern latitudes could disturb dormant microbial life that could one day prove harmful to man.

The latest find, described online Monday ... Read More

The day they discovered the AIDS virus

A historical look back at the discovery of the AIDS virus. Margaret Heckler, president Reagan's Health and Human Services Secretary made the announcement to the world. “First, the probable cause of AIDS has been found: a variant of a known human cancer virus. Second, not only has the agent been ... Read More

My No-Soap, No-Shampoo, Bacteria-Rich Hygiene Experiment

For most of my life, if I’ve thought at all about the bacteria living on my skin, it has been while trying to scrub them away. But recently I spent four weeks rubbing them in. I was Subject 26 in testing a living bacterial skin tonic, developed by AOBiome, a biotech start-up in Cambridge, Mass. ... Read More

"Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy" Infographic

The American Academy of Microbiology has just released a new report, "Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy," and along with it, an infographic, that summarizes the main points of the report. The full report can be found here: http://bit.ly/1lk346I, and a link t... Read More

Sweet Sweet Straw

The calorie free sweetener erythritol is widely used in Asia; it is also gaining popularity in Europe and America. At the Vienna University of Technology, a new cheap method has been developed to produce erythritol from straw with the help of mould fungi.

Erythritol has many great advantages:... Read More

Positive clinical results indicate vaccine candidate is highly efficacious against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. This repr... Read More

Tool to edit DNA revolutionizing research in Boston area

It is a fascinating quirk of nature: Simple bacteria have an immune system with a memory, which allows them to destroy invading viruses they have encountered in the past.

The phenomenon is more than just a scientific curiosity. In just two years, scientists have discovered how to repurpose th... Read More

How One Experimental Drug May Be Defeating Ebola and Saving People

Since the worst Ebola outbreak on record ignited last December in West Africa, scientists have been racing to develop drugs and vaccines to combat the virus. Several experimental drugs have been given to patients, and a new study details how scientists think one of those drugs might neutralize t... Read More

TWiV 303: Borna this way

The TWiV team discusses transmission of Ebola virus, and inhibition of Borna disease virus replication by viral DNA in the ground squirrel genome.


Hosts: Vincent Racaniello Read More

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