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Scientists Build a Yeast Chromosome From Scratch. Next Up? Designer Genomes

Creating synthetic organisms with specially-tailored genomes is a long way off, but the first synthetic eukaryotic chromosome is a big step forward.

Humans have been using what they know about the biological world to make stuff for centuries—from beer to antibiotics. But, what if you could ma... Read More

Early Exposure To Bacteria Protects Children From Asthma And Allergies

Babies who are exposed to both bacteria and allergens in the first year of life are less likely to develop asthma and allergies, a study finds.

It's the latest wrinkle in the hygiene hypothesis — the notion that exposure to bacteria trains the infant immune system to attack bad bugs and ignor... Read More

Freshman Biology Creative Projects!

I have found that students become involved, energized, and enthusiastic when I give them opportunities to explore topics in my classes using their own creative approaches and interests. So this semester, in my Biology 111 course at the University of Puget Sound, I found that students explored f... Read More

MoMA PS1's Mushroom Tower | Hy-Fi by The Living

For MoMA PS1's Young Architect Program, David Benjamin and the architecture firm, The Living, utilized cutting-edge bio-design technologies to create a completely organic, compostable tower. The winning structure is composed of discarded cornstalks and mushroom material, and used zero energy in ... Read More

Apes Have Better Gut Bugs than Humans

It's not a secret that the microbes living in our guts play a huge role in our well-being, or that, at least in the United States, we're doing a good job of killing them off.

But now new research finds that apes -- our closest relative -- have much more varied gut flora than humans do, and es... Read More

TWiV 319: Breaking breakbone

The TWiVers review the outcomes of two recent phase 3 clinical trials of a quadrivalent dengue virus vaccine in Asia and Latin America.


Hosts: Vincent Racaniello Read More

"Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy" Infographic

The American Academy of Microbiology has just released a new report, "Microbe-Powered Jobs: How Microbiologists Can Help Build the Bioeconomy," and along with it, an infographic, that summarizes the main points of the report. The full report can be found here: http://bit.ly/1lk346I, and a link t... Read More

TWiV 309: Ebola email

The TWiVocytes answer questions about Ebola virus, including mode of transmission, quarantine, incubation period, immunity, and much more.


 Hosts: Vincent Racaniello Read More

Cyanobacterium found in algae collection holds promise for biotech applications

Cyanobacteria could serve as a synthetic biology chassis that could be retooled for the production of biofuels, drugs or chemcials. So far, however, they have been held back by sluggish growth that makes it difficult to conduct the initial experiments needed to characterize their genetic and met... Read More

Hijacking bacteria's natural defences to trap and reveal pathogens

Bad bacteria could soon have no place left to hide, thanks to new materials that turn the cell’s own defences against them.

Scientists at The University of Nottingham and GSK Consumer Healthcare have developed a technique that could locate the potential source of an infection by hijacking the... Read More

BacterioFiles 202 - Controlling Coliform Computers

This episode: Programming bacteria to sense and keep genomic records of environmental inputs!


(15.9 MB, 17.4 minutes)


Show notes: 
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We Are Our Bacteria

Like ecosystems the world over, the human microbiome is losing its diversity, to the potential detriment of the health of those it inhabits.

Dr. Martin J. Blaser, a specialist in infectious diseases at the New York University School of Medicine and the director of the Human Microbiome Program... Read More

Bacteria Proposed for Passaic River Superfund Site Cleanup

A decades long fight over cleaning up one of the nation's most contaminated riverbeds has posed a difficult question: how to safely remove enough toxic material from New Jersey's Passaic River to fill two MetLife Stadiums.

The federal government is moving forward with long-stalled efforts to ... Read More

Parvo Trial Shows Promising Results In Effort To Combat Puppy Virus

A North Dakota company that discovered an antibody technology while trying to cure flocks of dying geese is using its research for a more warm and fuzzy purpose: saving puppies.

Early tests performed on about 50 puppies in seven U.S. states for Grand Forks-based Avianax have resulted in a 90 ... Read More

Highly Drug Resistant, Virulent, Strain of Pseudomonas Aeruginosa Arises in Ohio (press release)

A team of clinician researchers has discovered a highly virulent, multidrug resistant form of the pathogen, Pseudomonas aeruginosa, in patient samples in Ohio. Their investigation suggests that the particular genetic element involved, which is still rare in the United States, has been spreading ... Read More

BacterioFiles 188 - Rat Residents Relieve Resin Roughness

This episode: Gut bacteria in Mojave desert woodrats help them detoxify and eat toxic creosote bushes!


(10 MB, 10.8 minutes)


Show notes: 
News item/ Read More

Florida Bill Would Combat Superbug Threat

A bill to track drug-resistant infections has been introduced in Florida, inspired in part by FRONTLINE’s Hunting the Nightmare Bacteria.

The bill, sponsored by Rep. Janet Adkins, a Republican, requires the state health department to maintain an online record of the type and location of any a... Read More

Protein ID'd as possible universal therapeutic target for many infections, including Ebola

A protein called GRP78 could be a universal therapeutic target for treating human diseases like brain cancer, Ebola, Influenza, Hepatitis and superbug bacteria such as MRSE and MRSA, according to a Virginia Commonwealth University-led pre-clinical study published this month in the Journal of Cel... Read More

Artificial Spleen Cleans Ebola from Blood

Researchers have developed a high-tech method to rid the body of infections — even those caused by unknown pathogens. A device inspired by the spleen can quickly clean blood of everything from Escherichia coli to Ebola, researchers report on September 14 in Nature Medicine.

Blood infections c... Read More

New research shows how pathogenic E. coli O157:H7 binds to fresh vegetables

Food-poisoning outbreaks linked to disease-causing strains of the bacterium Escherichia coli are normally associated with tainted meat products. However, between 20-30% of these are caused by people eating contaminated vegetables, as was seen in the 2011 outbreak in Europe that caused 53 deaths.... Read More
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