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Florida citrus growers worry that deadly bacteria will mean end of orange juice

The sprawling citrus orchard that Victor Story toured recently sure looked like a steal at $11,000 an acre. The investors who owned it were going to lose money, and potential buyers such as Story might have stood to reap a handsome reward.

But as he bumped along the 40 acres of groves in a la... Read More

Rotavirus Activates Lymphocytes from Non-Obese Diabetic Mice by Triggering Toll-Like Receptor 7 Signaling and Interferon Production in Plasmacytoid Dendritic Cells

It has been proposed that rotavirus infection promotes the progression of genetically-predisposed children to type 1 diabetes, a chronic autoimmune disease marked by infiltration of activated lymphocytes into pancreatic islets. Non-obese diabetic (NOD) mice provide a model for the human disease.... Read More

Researchers open door to new HIV therapy

BERKELEY — People infected with the Human Immunodeficiency Virus (HIV) can stave off the symptoms of AIDS thanks to drug cocktails that mainly target three enzymes produced by the virus, but resistant strains pop up periodically that threaten to thwart these drug combos. Researchers at the Unive... Read More

Cilia use different motors for different tasks

Cilia — short, hair-like fibers — are widely present in nature. Single-celled paramecia use one set of cilia for locomotion and another set to sweep nutrients into their oral grooves. Researchers at Brown have discovered that those two cilia sets operate at different speeds when the viscosity of... Read More

Oral Bacteria and Cancer

Over a number of years, epidemiological studies established several well-defined risk factors for cancer, including age, heredity, diet, tobacco use, chronic viral infections, and inflammation. Paradoxically, the success of these studies left little room for incorporation of any new factors or c... Read More

Calcium makes for an environmentally friendly pickle

George Washington had a collection of 476 kinds of pickles. To prevent scurvy, Christopher Columbus stocked pickles on the Niña, Pinta, and Santa Maria. Julius Caesar, believing pickles to be invigorating, added them to the Roman legions' diet. In 5000 BCE, the Babylonians were known for picklin... Read More

Microbiome in gut, mouth, and skin of low birth weight infants differentiate over first weeks after birth

Low birth weight infants are host to numerous microorganisms immediately after birth, and the microbiomes of their mouths and gut start out very similar but differentiate significantly by day 15 according to a study in mBio this week. Researchers from Stanford University and the University of Pi... Read More

Staph Germs Hide Out In The Hidden Recesses Of Your Nose

Otherwise innocuous bacteria can cause deadly infections when people have surgery or fall ill. To prevent trouble, patients sometimes have their bodies scrubbed clean of Staphylococcus aureus. But it doesn't always work.

That may because the germs thrive in upper recesses of the nose, far fro... Read More

Bacteria show surprising number of genetic paths to survival

A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults from his immune system and antibiotics, while others perish. Eventually, the strongest m... Read More

Recalling the Good in the Good Old Days

In its early days, ca. 1945-1965, molecular biology was a particularly collegial undertaking, characterized by free sharing of research data and a relative lack of egotistical behavior. The reason for this marvel may well have been that there was so much to discover—so many low hanging fruits—th... Read More

Tiny Algae Responsible for Mysterious Fossil Whale Graveyard?

Ever since a highway construction crew in Chile uncovered a fossil graveyard of some 40 prehistoric whales in 2010, with skeletons dating back more than five million years, scientists have wondered why so many giant animals died in one place. This week, a team of them proposed an answer: The hug... Read More

Engineers design ‘living materials’ - Hybrid materials combine bacterial cells with nonliving elements that can conduct electricity or emit light

Inspired by natural materials such as bone — a matrix of minerals and other substances, including living cells — MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials, such as gold nanoparticles and quantum dots.

These “living materials” combin... Read More

Warmer temperatures push malaria to higher elevations

Researchers have debated for more than two decades the likely impacts, if any, of global warming on the worldwide incidence of malaria, a mosquito-borne disease that infects more than 300 million people each year. University of Michigan ecologists and their colleagues are reporting the first har... Read More

ULTRASMALL BACTERIA FROM ANTARCTIC LAKE RAISE QUESTIONS ABOUT THE LIMITS OF LIFE

Imagine you were forced to live in perpetually subzero temperatures, with no oxygen, no light, and way more salt than your system could handle. How would you manage? One way might be to get extremely small. At least, that seems to be what’s happening in a frozen Antarctic lake that’s cut off fro... Read More

UNC researchers discover new target for dengue virus vaccine

Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More

Bacterial Gut Biome May Guide Colon Cancer Progression

Colorectal cancer develops in what is probably the most complex environment in the human body, a place where human cells cohabitate with a colony of approximately 10 trillion bacteria, most of which are unknown. At the 2014 American Association for Cancer Research Annual Meeting in San Diego, re... Read More

Family Tree Of Pertussis Traced, Could Lead To Better Vaccine

Whooping cough was once one of the leading killers of babies around the world. Now that it's largely controlled with a vaccine, scientists have had a chance to figure out how the disease came into being in the first place. That story is told in a study published online this week in the journal m... Read More

Urease: an anti-microbial target in bacteria and fungi

Urea is a small molecule formed as proteins are broken down. It’s excreted in urine, but isn’t particularly toxic at low levels so it’s found in cells throughout the body. The molecular structure of urea is below, and as it contains nitrogen (N) several pathogens have adapted to use it as a nitr... Read More

Diversity of Antiviral Bacteria Discovered

Wolbachia, a symbiont that resides naturally up to 70% of all insect species, are probably the most prevalent infectious bacteria on Earth. In 2008 Luis Teixeira, now a principal investigator at the Instituto Gulbenkian de Ciência, and other scientists have discovered that Wolbachia can protect ... Read More

A Snippet: Antibiotics In The Nursery

You have heard of the leaf-cutting ants1 that meticulously cultivate "their" fungi2 which provide them with nutrients, and that, in addition, host actinobacteria which prevent bacterial and fungal infections of their fungi as well as their own infection by an entomopathogenic fungus3 Metarhizium... Read More

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