Whooping cough was once one of the leading killers of babies around the world. Now that it's largely controlled with a vaccine, scientists have had a chance to figure out how the disease came into being in the first place. That story is told in a study published online this week in the journal m... Read More
In its early days, ca. 1945-1965, molecular biology was a particularly collegial undertaking, characterized by free sharing of research data and a relative lack of egotistical behavior. The reason for this marvel may well have been that there was so much to discover—so many low hanging fruits—th... Read More
If you pull up a soybean or bean plant and shake off the dirt, you might see odd swellings or bumps, like rheumatic finger joints, on its roots. Inside the cool, soil-covered bumps are bacteria that are making nitrogen with the help of an enzyme, something chemical factories can do only with the... Read More
Researchers at Bigelow Laboratory for Ocean Sciences dug into the last 70 years of peer-reviewed publications about protozoan parasites that infest bivalve mollusks and found that when an organism can be cultured in the laboratory, more papers and greater understanding result. Senior Research S... Read More
The 'post-antibiotic' era is near, according to a report released today by the World Health Organization (WHO). The decreasing effectiveness of antibiotics and other antimicrobial agents is a global problem, and a surveillance system should be established to monitor it, the group says. There is ... Read More
Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More
Ever since a highway construction crew in Chile uncovered a fossil graveyard of some 40 prehistoric whales in 2010, with skeletons dating back more than five million years, scientists have wondered why so many giant animals died in one place. This week, a team of them proposed an answer: The hug... Read More
Common gut bacteria prevent sensitization to allergens in a mouse model for peanut allergy, paving the way for probiotic therapies to treat food allergies.
The presence of Clostridia, a common class of gut bacteria, protects against food allergies, a new study in mice finds. By inducing immun... Read More
Banana lovers take note: The world's supply of the fruit is under attack from a fungus strain that could wipe out the popular variety that Americans eat. "It's a very serious situation," said Randy Ploetz, a professor of plant pathology at the University of Florida who in 1989 originally discove... Read More
Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
The instructions encoded into DNA are thought to follow a universal set of rules across all domains of life. But researchers report in the May 23 issue of Science that organisms routinely break these rules.
The finding has implications for the design of synthetic life: by designing organisms ... Read More
A graduate student came to my office recently to say that she was increasingly bothered by anxiety and the ‘terror’ of having to speak at laboratory meetings. She had also learned a month ago that she was expected to lecture to a class organized by her mentor. The thought of having to lecture to... Read More
New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.
In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More
Making hydrogen easily and cheaply is a dream goal for clean, sustainable energy. Bacteria have been doing exactly that for billions of years, and now chemists at the University of California, Davis, and Stanford University are revealing how they do it, and perhaps opening ways to imitate them.
... Read More
For scientists tracking the deadly Ebola virus in West Africa, it is not about complex virology and genotyping, but about how contagious microbes - like humans - use planes, bikes and taxis to spread.
So far, authorities have taken no action to limit international travel in the region. The ai... Read More
Infections in the central nervous system are rare thanks to our brain's unique defence system that prevents viruses from invading, finds a study. The research explains a long-standing mystery.
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Researchers have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern humans -- H... Read More
Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago, but new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years – long before any humans walked on Earth.
The findings w... Read More
A University of Florida research team is cautiously optimistic after finding a possible treatment in the lab for citrus greening, a disease devastating Florida’s $9 billion citrus industry. It is the first step in a years-long process to bring a treatment to market.
Claudio Gonzalez and Graci... Read More
If a sexually active woman wants to protect herself from unwanted pregnancy and HIV using a single method, she has always been limited to condoms. A new paper, released today in PLOS ONE details a first-of-its-kind device that provides an alternative.
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