Researchers have identified the evolutionary origins of human herpes simplex virus (HSV) -1 and -2, reporting that the former infected hominids before their evolutionary split from chimpanzees 6 million years ago while the latter jumped from ancient chimpanzees to ancestors of modern humans -- H... Read More
A boy with cystic fibrosis develops a chronic and potentially deadly Burkholderia dolosa infection in his lungs. Varieties of genetic mutations allow some strains of the bacteria to survive the dual assaults from his immune system and antibiotics, while others perish. Eventually, the strongest m... Read More
The instructions encoded into DNA are thought to follow a universal set of rules across all domains of life. But researchers report in the May 23 issue of Science that organisms routinely break these rules.
The finding has implications for the design of synthetic life: by designing organisms ... Read More
Using a new technique to track the swimming motion of a single bacterium, researchers have discovered that the movement of the bacterium’s body — not just thrust from the flagellum — allow movement through fluids. The finding could shed new light on the evolution of cell body shape.
Click "so... Read More
Inspired by natural materials such as bone — a matrix of minerals and other substances, including living cells — MIT engineers have coaxed bacterial cells to produce biofilms that can incorporate nonliving materials, such as gold nanoparticles and quantum dots.
These “living materials” combin... Read More
Using an experimental technique new to the dengue field, the labs of Ralph Baric, PhD, and Aravinda de Silva, PhD, showed that a molecular hinge where two regions of a protein connect is where natural human antibodies attach to dengue 3 to disable it. The finding, published in the Proceedings of... Read More
Could Ebola go airborne? That’s the fear set off last week by a New York Times op-ed entitled “What We’re Afraid to Say about Ebola” from Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota. Although clinicians readily agree that th... Read More
Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs.
“Anthrax toxin ... Read More
According to CNN,a long-range business jet with an isolation pod left the United States for Liberia, where it will evacuate two Americans infected with Ebola.
Twitter exploded with questions about the deadly virus, which according to the World Health Organization is believed to have killed hu... Read More
Banana lovers take note: The world's supply of the fruit is under attack from a fungus strain that could wipe out the popular variety that Americans eat. "It's a very serious situation," said Randy Ploetz, a professor of plant pathology at the University of Florida who in 1989 originally discove... Read More
Methicillin-resistant S. aureus (MRSA) constitutes approximately 50% of clinical S. aureus isolates and is most commonly the result of production of a mutated pencillin-binding protein, PBP2a, which is able to carry out essential cell wall synthesis functions while maintaining a low-affinity for... Read More
Scientists regularly tap into biological systems to find solutions for human problems. Although they work with plants and viruses in the lab, bacteria have many advantages as a starting point. When programmed in certain ways, bacteria can store data, clean dangerous waste, produce film-like imag... Read More
Ever since a highway construction crew in Chile uncovered a fossil graveyard of some 40 prehistoric whales in 2010, with skeletons dating back more than five million years, scientists have wondered why so many giant animals died in one place. This week, a team of them proposed an answer: The hug... Read More
A graduate student came to my office recently to say that she was increasingly bothered by anxiety and the ‘terror’ of having to speak at laboratory meetings. She had also learned a month ago that she was expected to lecture to a class organized by her mentor. The thought of having to lecture to... Read More
New research reveals the complex dynamic between gut bacteria and the immune system that keeps proteins from flagellin—bacterial tails—under control.
In healthy individuals, the only thing that separates the lining of the human gut from the some 100 trillion bacterial cells in the gastrointes... Read More
Low birth weight infants are host to numerous microorganisms immediately after birth, and the microbiomes of their mouths and gut start out very similar but differentiate significantly by day 15 according to a study in mBio this week. Researchers from Stanford University and the University of Pi... Read More
In the United States, approximately 40,000 people die every year due to pancreatic adenocarcinoma, making it the fourth leading cause of cancer related death. Patients diagno... Read More
Lyme disease is a stealthy, often misdiagnosed disease that was only recognized about 40 years ago, but new discoveries of ticks fossilized in amber show that the bacteria which cause it may have been lurking around for 15 million years – long before any humans walked on Earth.
The findings w... Read More
Scientists have modified mosquitoes to produce sperm that will only create males, pioneering a fresh approach to eradicating malaria. Since 2000, increased prevention and control measures have reduced global malaria mortality rates by 42 per cent, but the disease remains a prevalent killer espec... Read More
Influenza infection can enhance the ability of the bacterium Streptococcus pneumoniae to cause ear and throat infections, according to research published ahead of print in the journal Infection and Immunity.
In the study, the investigators infected mice with either influenza alone, pneumococc... Read More