Harvard stem cells scientists at Brigham and Women’s Hospital and MIT can now engineer cells that are more easily controlled following transplantation, potentially making cell therapies, hundreds of which are currently in clinical trials across the United States, more functional and efficient.
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There is no approved medicine to treat polyomaviruses, which afflict people with weakened immune systems, but scientists have found that a chemical compound called Retro-2 is able to reduce significantly the infectivity and spread of the viruses in lab cell cultures. Now they are working to impr... Read More
In May 1984, readers of an article by Schwartz and Cantor in the prestigious journal Cell were to stumble upon pictures of DNA agarose gels that were among the lousiest of such ever published after the method was introduced in the early 70s. Why did the editors of Cell risk their reputation? Or ... Read More
Slothful response from regulators and manufacturers means antibiotic resistance is missed. Bacteria that are resistant to almost all antibiotics are dreaded by physicians and patients alike. Finding such microbes in a hospital is bad enough, but failing to detect them can lead to something much ... Read More
Health officials are still learning from the fungal outbreak tied to tainted steroid pain injections made at the now-shuttered New England Compounding Company.
Researchers now know that most patients' immune systems didn't try to fight off the deadly fungi as it burrowed into their spinal col... Read More
Viruses are supposed to be small and simple—not even alive, just mobile genetic material after all. So what do we make of giant double-stranded DNA (dsDNA) viruses, one of which—the newly discovered Pandoravirus salinus—has an even larger genome than a hunky parasitic eukaryote called Encephalit... Read More
A UAB research concludes that the Streptococcus mutans, one of the principal bacteria causing dental caries, has increased the changes in its genetic material over time, possibly coinciding with dietary changes linked to the expansion of humanity.
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Twitter clips human thoughts to a mere 140 characters. Animals’ scent posts may be equally as short, relatively speaking, yet they convey an encyclopedia of information about the animals that left them.
In the current issue of the Proceedings of the National Academy of Sciences, a Michigan St... Read More
The EU Commission has agreed new rules to limit the spread of a deadly swine disease that has killed millions of piglets in the US.
Porcine Epidemic Diarrhoea virus (PEDv) has wiped out around 10% of the American herd in a year.
While the EU rejected an outright ban on live pig imports, it... Read More
To the collection of avian influenza viruses known to sporadically infect humans – H5N1, H7N9, H7N2, H7N3, H7N7, H9N2, and H10N7 – we can now add H10N8, recently found in two individuals in China. Avian influenza virus H10N8 was first detected in tracheal aspirates from a 73 year old woman who w... Read More
A new type of botulinum toxin – the deadliest substance known – has been discovered. Because it does not yet have an antidote, the DNA sequence behind it has been withheld from public databases. This is the first time a sequence has been kept secret over security concerns.
Injecting a mere 2 ... Read More
The Human Microbiome Project (HMP) is a global initiative to identify and characterize the microorganisms present at multiple sites in the human body. An international team of researchers reports on new ways to harness the results of the HMP and discusses how changes in the microbiome might affe... Read More
An international consortium led by CEA researchers in collaboration with the CNRS, has succeeded in characterizing the structure and function of a protein involved in the production of magnetite nanomagnets in magnetotactic bacteria. This protein, MamP, is crucial to the metallurgical activity o... Read More
Evolution is relentless process that seems to keep going and going, even when creatures live in a stable, unchanging world.
That's the latest surprise from a unique experiment that's been underway for more than a quarter-century.
Evolution is so important for biology, medicine and a genera... Read More
Soil deep in a crater dating to some 3.7 billion years ago contains evidence that Mars was once much warmer and wetter, says University of Oregon geologist Gregory Retallack, based on images and data captured by the rover Curiosity.
NASA rovers have shown Martian landscapes littered with loos... Read More
Scientists say that culling a small number of badgers risks increasing the spread of TB infection to cattle.
The research suggests that some farmers who have allegedly killed badgers on their property could be making things worse for themselves and neighbours.
The findings also indicate th... Read More
Scientists in Canada have developed a paper-based device that checks if bacteria are resistant to certain antibiotics. The simple system could help users in remote areas pick the most appropriate treatment for bacterial infections.
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A report in Biology Letters shows that the drool of herbivores might help defeat the toxic fungal defences of the plants they graze on.
Grazing or cutting some plants induces a noxious chemical to be produced which deters hungry plant-eaters from revisiting them. The chemicals, called alkaloi... Read More
Multiple sclerosis (MS), a central nervous system disease that often leads to paralysis and vision problems, affects approximately 2.3 million people worldwide and has no cure. Though no one knows what triggers MS, researchers have long suspected that a combination of genetic and environmental f... Read More
Australian researchers have found that zinc can 'starve' one of the world's most deadly bacteria by preventing its uptake of an essential metal.
The finding, by infectious disease researchers at the University of Adelaide and The University of Queensland, opens the way for further work to des... Read More