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Grand Challenge: Mapping the Human Immune System

A team of scientists has created a genetic map of all possible receptors the human immune system might generate—also known as the immunome.

The project involved a mind-boggling data set.

“If we were on a treasure hunt, where the cure to many illnesses is the buried treasure, then we’ve jus... Read More

TWiV 409: A Nef is enough

Jeremy joins the TWiVeroids to tell the amazing story of how the function of the HIV-1 protein called Nef was discovered and found to promote infection by excluding the host protein SERINC from virus particles.

Hosts:  Read More

Zika likely to spread in Asia Pacific: WHO

The Zika virus is set to spread through Asia, the World Health Organization warned Monday, with hundreds of cases reported in Singapore and two Thai babies diagnosed with Zika-linked microcephaly.

The mosquito-borne virus has been detected in 70 countries worldwide including at least 19 count... Read More

Complete Genome Sequence of Zika Virus Isolated from Semen

A team of researchers from the United Kingdom has obtained the first complete genome sequence of Zika virus that was isolated from a semen sample. The research is published this week in Genome Announcements, a journal of the American Society for Microbiology.

The motivation for this investiga... Read More

Microbes in the breast may play a role in breast cancer

The gut microbiome has stolen the show when it comes to the recent explosion of research on the bacteria that thrive within us. But bacteria also live in a woman's breast tissue—and the mix of those microbes may have an equally important effect on health, according to a new study in Applied and ... Read More

How cells take out the trash—phosphoarginine deciphered

Cells never forget to take out the trash. It has long been known that cells tag proteins for degradation by labelling them with ubiquitin, a signal described as "the molecular kiss of death". Tim Clausen's group at the Research Institute of Molecular Pathology (IMP) in Vienna identified an analo... Read More

Autophagy, Illustrated (infographic)

Earlier this week, Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for his work on the underlying mechanisms of autophagy—the process by which cells break down and recycle their own contents. How does autophagy work? Here are the basics, as drawn for the article “How ... Read More

A fungal infection that could help researchers to understand some allergies

Researchers from UPM have revealed how mold from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.

A team of researchers from Centre for Plant Biotechnology and Genomics (CBGP, UPM-INIA), has published the results on Alt a1 in an article release... Read More

Microscope will seek biological samples on red planet

One of the ultimate goals of Mars exploration is to bring samples from the surface to Earth, especially those that could be examined for evidence of life on the Red Planet.

Such an undertaking would be expensive and the samples risk contamination during their journey to Earth. So, one option ... Read More

Mix and match microbes to make probiotics last

Scientists have tried to alter the human gut microbiota to improve health by introducing beneficial probiotic bacteria. Yet commercially available probiotics do not establish themselves in the gut. A study published September 29 in Cell Host & Microbe suggests that it is possible to alter the mi... Read More

Women don’t feel welcome in these STEM fields

Researchers say there are 3 main factors that explain why women are more represented in some STEM (science, technology, engineering, and mathematics) fields than others.

The most powerful one, they say, is a “masculine culture” that makes many women feel like they don’t belong.

“There is w... Read More

Research provides clues to how Zika virus breaches the placental barrier

New research reveals that in pregnant women, Zika virus infection damages certain cells that affect placental formation and function. Furthermore, herpes simplex virus-2 (HSV-2) infection augments placental sensitivity to Zika virus by enhancing the expression of receptors that allow Zika virus ... Read More

New Discovery Offers Hope for Crohn’s Disease

Exciting new research in the medical journal MBio, the journal of the American Society for Microbiology, offers hope for sufferers of the debilitating illness known as Crohn’s Disease.

Crohn’s is an inflammatory bowel disease (IBD) that involves inflammation of the lining of the bowels and th... Read More

TWiV 411: Chicken runs

The TWiVeroos examine a reverse spillover of Newcastle disease virus vaccines into wild birds, and identification of a protein cell receptor for murine noroviruses.

Hosts: Vincent Racaniel... Read More

Zika virus infection may prevent reinfection, collaborative study finds

People infected with Zika virus may not be susceptible to Zika virus again, according to the latest research involving Kansas State University's Biosecurity Research Institute.

"The research shows that infection provides excellent protection against reinfection," said Stephen Higgs, director ... Read More

Plankton blooms in New Zealand suggest the ocean is responding to climate change

The appearance of white blooms of plankton east of New Zealand suggests the ocean is responding to climate change, according to research by Victoria University of Wellington scientists.

As part of her Master's study, Bella Duncan investigated coccolithophores, a white algae with remains known... Read More

Culex mosquitoes do not transmit Zika virus, Kansas State University study finds

A Biosecurity Research Institute study has found important results in the fight against Zika virus: Culex mosquitoes do not appear to transmit Zika virus.

Researchers at Kansas State University's Biosecurity Research Institute studied Culex species mosquitoes from across the country, includin... Read More

BacterioFiles 270 - Bacteria Block Bug Babies

This episode: Insect gut microbes can be engineered to act as birth control, population control, or disease control for bugs!

(13.3 MB, 14.5 minutes)

Show notes: 

Read More

Yoshinori Ohsumi of Japan Wins Nobel Prize in Medicine

Yoshinori Ohsumi, a Japanese cell biologist and ASM member, was awarded the Nobel Prize in Physiology or Medicine on Monday for his discoveries on how cells recycle their content, a process known as autophagy.

In a series of experiments in the early 1990s, Dr. Ohsumi used baker’s yeast to ide... Read More

BacterioFiles 272 - Parasite Prevents Pollution Poisoning

This episode: Worm parasites infecting brine shrimp help them survive better in arsenic-polluted environments!

(7.9 MB, 8.6 minutes)

Show notes: 
Read More

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